How cellular suicide programmes control phase transitions in fatty liver disease and liver cancer

Informacje na temat projektu

PhaseControl

Identyfikator umowy o grant: 771083

DOI

10.3030/771083

Projekt został zamknięty

Data podpisania przez KE 15 Maja 2018

Data rozpoczęcia 1 Listopada 2018

Data zakończenia 30 Kwietnia 2025

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 997 840,00

Wkład UE

€ 1 997 840,00

Koordynowany przez

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (40)

Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany

Autorzy: Sven H Loosen, David Schöler, Mark Luedde, Johannes Eschrich, Tom Luedde, Karel Kostev, Christoph Roderburg
Opublikowane w: Journal of Cancer Research and Clinical Oncology, 2022, ISSN 0171-5216
Wydawca: Springer Verlag
DOI: 10.1007/s00432-022-04198-5

The association between the body height and cardiovascular diseases: a retrospective analysis of 657,310 outpatients in Germany

Autorzy: Sarah Krieg, Karel Kostev, Mark Luedde, Andreas Krieg, Tom Luedde, Christoph Roderburg, Sven H Loosen
Opublikowane w: European Journal of Medical Research, Numer 27/1, 2022, Strona(/y) 240, ISSN 0949-2321
Wydawca: Holzapfel Verlag GmbH
DOI: 10.1186/s40001-022-00881-y

Deep learning in cancer pathology: a new generation of clinical biomarkers

Autorzy: Amelie Echle, Niklas Timon Rindtorff, Titus Josef Brinker, Tom Luedde, Alexander Thomas Pearson, Jakob Nikolas Kather
Opublikowane w: British Journal of Cancer, Numer 124, 2023, Strona(/y) 686-696, ISSN 0007-0920
Wydawca: Nature Publishing Group
DOI: 10.1038/s41416-020-01122-x

Circulating Osteopontin Levels and Outcomes in Patients Hospitalized for COVID-19

Autorzy: Salim S Hayek, Christoph Roderburg, Pennelope Blakely, Christopher Launius, Jesper Eugen-Olsen, Frank Tacke, Sofia Ktena, Verena Keitel, Mark Luedde, Evangelos J Giamarellos-Bourboulis, Tom Luedde, Sven H Loosen
Opublikowane w: Journal of Clinical Medicine, Numer 10/17, 2021, Strona(/y) 3907, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10173907

An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration

Autorzy: Koppe, Reisinger, Wehr, Vucur, Trautwein, Tacke, Heikenwalder, Luedde
Opublikowane w: Cancers, Numer 11/7, 2019, Strona(/y) 999, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11070999

An Elevated FIB-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany

Autorzy: David Schöler; Karel Kostev; Münevver Demir; Mark Luedde; Marcel Konrad; Tom Luedde; Christoph Roderburg; Sven H. Loosen
Opublikowane w: Journal of Clinical Medicine, Numer 11/8, 2022, Strona(/y) 2214, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11082214

Hospital Mortality and Current Trends in Liver Transplantation in Germany — a Systematic Analysis of Standardized Hospital Discharge Data, 2008–2017

Autorzy: Sven H Loosen, Hans H Bock, Martin Hellmich, Wolfram T. Knoefel, Christian Trautwein, Verena Keitel, Johannes G. Bode, Ulf P. Neumann, Tom Luedde
Opublikowane w: Deutsches Ärzteblatt International, Numer 118/29-30, 2021, Strona(/y) 497-502, ISSN 1866-0452
Wydawca: Deutscher Arzte-Verlag
DOI: 10.3238/arztebl.m2021.0210

Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer

Autorzy: Sven H Loosen, Justus Halpaap, Simon Labuhn, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sven A Lang, Mihael Vucur, Jakob N Kather, Wolfram T Knoefel, Tom F Ulmer, Ulf P Neumann, Christoph Roderburg, Tom Luedde
Opublikowane w: Cancers, Numer 14/18, 2022, Strona(/y) 4428, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14184428

Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey

Autorzy: Pia Paffenholz, Arne Peine, Martin Hellmich, Stella V. Paffenholz, Lukas Martin, Mark Luedde, Miriam Haverkamp, Christoph Roderburg, Gernot Marx, Axel Heidenreich, Christian Trautwein, Tom Luedde, Sven H. Loosen
Opublikowane w: Emerging Microbes & Infections, Numer 9/1, 2020, Strona(/y) 1590-1599, ISSN 2222-1751
Wydawca: Nature Publishing Group
DOI: 10.1080/22221751.2020.1785951

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

Autorzy: Benjamin Rolles, Joao Gorgulho, Mareike Tometten, Christoph Roderburg, Margherita Vieri, Anne Abels, Mihael Vucur, Felix Heymann, Frank Tacke, Tim H Brümmendorf, Tom Luedde, Fabian Beier, Sven H Loosen
Opublikowane w: Frontiers in Oncology, Numer 11, 2021, Strona(/y) 729207, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.729207

Factors Associated with Non-Severe Adverse Reactions after Vaccination against SARS-CoV-2: A Cohort Study of 908,869 Outpatient Vaccinations in Germany

Autorzy: Sven H Loosen, Jens Bohlken, Kerstin Weber, Marcel Konrad, Tom Luedde, Christoph Roderburg, Karel Kostev
Opublikowane w: Vaccines, Numer 10/4, 2022, Strona(/y) 566, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10040566

A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development

Autorzy: Anne T. Schneider, Christiane Koppe, Emilie Crouchet, Aristeidis Papargyriou, Michael T. Singer, Veronika Büttner, Leonie Keysberg, Marta Szydlowska, Frank Jühling, Julien Moehlin, Min-Chun Chen, Valentina Leone, Sebastian Mueller, Thorsten Neuß, Mirco Castoldi, Marina Lesina, Frank Bergmann, Thilo Hackert, Katja Steiger, Wolfram T. Knoefel, Alex Zaufel, Jakob N. Kather, Irene Esposito, Matthia
Opublikowane w: Nature Communications, Numer 16, 2025, Strona(/y) 1765, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-025-56493-7

Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients

Autorzy: Sven H Loosen, Björn-Erik Ole Jensen, Christian Tanislav, Tom Luedde, Christoph Roderburg, Karel Kostev
Opublikowane w: Infection, 2022, Strona(/y) 1-6, ISSN 0300-8126
Wydawca: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s15010-022-01784-0

Pan-cancer image-based detection of clinically actionable genetic alterations

Autorzy: Jakob Nikolas Kather, Lara R. Heij, Heike I. Grabsch, Chiara Loeffler, Amelie Echle, Hannah Sophie Muti, Jeremias Krause, Jan M. Niehues, Kai A. J. Sommer, Peter Bankhead, Loes F. S. Kooreman, Jefree J. Schulte, Nicole A. Cipriani, Roman D. Buelow, Peter Boor, Nadina Ortiz-Brüchle, Andrew M. Hanby, Valerie Speirs, Sara Kochanny, Akash Patnaik, Andrew Srisuwananukorn, Hermann Brenner, Michael Hoff
Opublikowane w: Nature Cancer, Numer 1/8, 2020, Strona(/y) 789-799, ISSN 2662-1347
Wydawca: Springer Nature
DOI: 10.1038/s43018-020-0087-6

Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy

Autorzy: Joao Gorgulho, Sven H. Loosen, Ramsha Masood, Franziska Giehren, Francesca Pagani, Gustav Buescher, Lorenz Kocheise, Vincent Joerg, Constantin Schmidt, Kornelius Schulze, Christoph Roderburg, Eva Kinkel, Britta Fritzsche, Simon Wehmeyer, Benjamin Schmidt, Paul Kachel, Christina Rolling, Julian Götze, Alina Busch, Marianne Sinn, Thais Pereira-Veiga, Harriet Wikman, Maria Geffken, Sven Peine, Urte
Opublikowane w: Journal of Experimental & Clinical Cancer Research, Numer 43, 2024, Strona(/y) 298, ISSN 1756-9966
Wydawca: BMC
DOI: 10.1186/s13046-024-03215-4

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Autorzy: Jakob Nikolas Kather, Alexander T. Pearson, Niels Halama, Dirk Jäger, Jeremias Krause, Sven H. Loosen, Alexander Marx, Peter Boor, Frank Tacke, Ulf Peter Neumann, Heike I. Grabsch, Takaki Yoshikawa, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Christian Trautwein, Tom Luedde
Opublikowane w: Nature Medicine, Numer 25/7, 2019, Strona(/y) 1054-1056, ISSN 1078-8956
Wydawca: Nature Publishing Group
DOI: 10.1038/s41591-019-0462-y

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Autorzy: Ahmed Ghallab, Reham Hassan, Ute Hofmann, Adrian Friebel, Zaynab Hobloss, Lisa Brackhagen, Brigitte Begher-Tibbe, Maiju Myllys, Joerg Reinders, Nina Overbeck, Selahaddin Sezgin, Sebastian Zühlke, Abdel-Latif Seddek, Walaa Murad, Tim Brecklinghaus, Franziska Kappenberg, Jörg Rahnenführer, Daniela González, Christopher Goldring, Ian M Copple, Rosemarie Marchan, Thomas Longerich, Mihael Vucur, To
Opublikowane w: Journal of Hepatology, Numer 77/1, 2022, Strona(/y) 71-83, ISSN 0168-8278
Wydawca: Elsevier BV
DOI: 10.1016/j.jhep.2022.01.020

Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients.

Autorzy: Maximilian Schulze-Hagen; Christoph Roderburg; Theresa H. Wirtz; Markus S. Jördens; Lukas Bündgens; Samira Abu Jhaisha; Philipp Hohlstein; Jonathan F. Brozat; Philipp Bruners; Christina Loberg; Christiane K. Kuhl; Christian Trautwein; Frank Tacke; Tom Luedde; Sven H. Loosen; Alexander Koch
Opublikowane w: Journal of Clinical Medicine, Numer 10/16, 2021, Strona(/y) 3741, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10163741

JNK signaling prevents biliary cyst formation through a CASPASE-8–dependent function of RIPK1 during aging

Autorzy: Katrin Müller, Hanna Honcharova-Biletska, Christiane Koppe, Michèle Egger, Lap Kwan Chan, Anne T. Schneider, Lena Küsgens, Friederike Böhm, Yannick Boege, Marc E. Healy, Johannes Schmitt, Sarah Comtesse, Mirco Castoldi, Christian Preisinger, Marta Szydlowska, Enrico Focaccia, Nadine T. Gaisa, Sven H. Loosen, Simone Jörs, Frank Tacke, Christoph Roderburg, Verena Keitel, Johannes G. Bode, Peter
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 118/12, 2021, Strona(/y) e2007194118, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2007194118

Soluble lymphocyte activation gene-3 (sLAG3) and CD4/CD8 ratio dynamics as predictive biomarkers in patients undergoing immune checkpoint blockade for solid malignancies

Autorzy: Joao Gorgulho, Christoph Roderburg, Fabian Beier, Carsten Bokemeyer, Tim H. Brümmendorf, Sven H. Loosen, Tom Luedde
Opublikowane w: British Journal of Cancer, Numer 130, 2024, Strona(/y) 1013-1022, ISSN 0007-0920
Wydawca: Nature Publishing Group
DOI: 10.1038/s41416-023-02558-7

Non-Alcoholic Fatty Liver Disease (NAFLD) and risk of new-onset heart failure: a retrospective analysis of 173,966 patients

Autorzy: Christoph Roderburg, Sarah Krieg, Andreas Krieg, Sascha Vaghiri, Raphael Mohr, Marcel Konrad, Mark Luedde, Tom Luedde, Karel Kostev, Sven H. Loosen
Opublikowane w: Clinical Research in Cardiology, Numer 112, 2023, Strona(/y) 1446-1453, ISSN 1861-0684
Wydawca: Steinkopff
DOI: 10.1007/s00392-023-02250-z

Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019

Autorzy: Christoph Roderburg, Tobias Essing, Linde Kehmann, Sarah Krieg, Simon Labuhn, Jennis Kandler, Tom Luedde, Sven H Loosen
Opublikowane w: Cancers, Numer 14/16, 2022, Strona(/y) 4038, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14164038

Circulating levels of microRNA193a-5p predict outcome in early stage hepatocellular carcinoma

Autorzy: Sven H. Loosen, Theresa H. Wirtz, Sanchari Roy, Mihael Vucur, Mirco Castoldi, Anne T. Schneider, Christiane Koppe, Tom F. Ulmer, Anjali A. Roeth, Jan Bednarsch, Patrick H. Alizai, Pia Paffenholz, Münevver Demir, Christian Trautwein, Frank Tacke, Ulf P. Neumann, Christoph Roderburg, Tom Luedde
Opublikowane w: PLOS ONE, Numer 15/9, 2020, Strona(/y) e0239386, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0239386

Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies

Autorzy: Joao Gorgulho, Christoph Roderburg, Felix Heymann, Maximilian Schulze‐Hagen, Fabian Beier, Mihael Vucur, Jakob N. Kather, Narmin Ghaffari Laleh, Frank Tacke, Tim H. Brümmendorf, Tom Luedde, Sven H. Loosen
Opublikowane w: International Journal of Cancer, Numer 149/5, 2021, Strona(/y) 1189-1198, ISSN 0020-7136
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33610

Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer

Autorzy: Sven H. Loosen, Mark Luedde, Georg Lurje, Martina Spehlmann, Pia Paffenholz, Tom Florian Ulmer, Frank Tacke, Mihael Vucur, Christian Trautwein, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Opublikowane w: Disease Markers, Numer 2019, 2019, Strona(/y) 1-8, ISSN 0278-0240
Wydawca: IOS Press
DOI: 10.1155/2019/5603474

The Role of Adipokines as Circulating Biomarkers in Critical Illness and Sepsis

Autorzy: Sven H. Loosen, Alexander Koch, Frank Tacke, Christoph Roderburg, Tom Luedde
Opublikowane w: International Journal of Molecular Sciences, Numer 20/19, 2019, Strona(/y) 4820, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20194820

Sublethal necroptosis signaling promotes inflammation and liver cancer

Autorzy: Mihael Vucur, Ahmed Ghallab, Anne T Schneider, Arlind Adili, Mingbo Cheng, Mirco Castoldi, Michael T Singer, Veronika Büttner, Leonie S Keysberg, Lena Küsgens, Marlene Kohlhepp, Boris Görg, Suchira Gallage, Jose Efren Barragan Avila, Kristian Unger, Claus Kordes, Anne-Laure Leblond, Wiebke Albrecht, Sven H Loosen, Carolin Lohr, Markus S Jördens, Anne Babler, Sikander Hayat, David Schumacher, M
Opublikowane w: Immunity, Numer 56/7, 2023, Strona(/y) 1578-1595, ISSN 1074-7613
Wydawca: Cell Press
DOI: 10.1016/j.immuni.2023.05.017

Serum Levels of CXCL13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer

Autorzy: Sven H Loosen, Tom F Ulmer, Simon Labuhn, Jan Bednarsch, Sven A Lang, Patrick H Alizai, Anne T Schneider, Mihael Vucur, Ulf P Neumann, Tom Luedde, Christoph Roderburg
Opublikowane w: Cancers, Numer 14/14, 2022, Strona(/y) 4073, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14174073

Adult Body Height Is Associated with the Risk of Type 2 but Not Type 1 Diabetes Mellitus: A Retrospective Cohort Study of 783,029 Individuals in Germany

Autorzy: Sven H Loosen, Sarah Krieg, Andreas Krieg, Tom Luedde, Karel Kostev, Christoph Roderburg
Opublikowane w: Journal of Clinical Medicine, Numer 12/6, 2023, Strona(/y) 2199, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm12062199

Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autorzy: Sven H. Loosen, Joao Gorgulho, Markus S. Jördens, Maximilian Schulze-Hagen, Fabian Beier, Mihael Vucur, Anne T. Schneider, Christiane Koppe, Alexander Mertens, Jakob N. Kather, Frank Tacke, Verena Keitel, Tim H. Brümmendorf, Christoph Roderburg, Tom Luedde
Opublikowane w: Frontiers in Oncology, Numer 11, 2021, ISSN 2234-943X
Wydawca: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.646883

Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autorzy: Sven H. Loosen, Vincent van den Bosch, Joao Gorgulho, Maximilian Schulze-Hagen, Jennis Kandler, Markus S. Jördens, Frank Tacke, Christina Loberg, Gerald Antoch, Tim Brümmendorf, Ulf P. Neumann, Christiane Kuhl, Tom Luedde, Christoph Roderburg
Opublikowane w: Journal of Clinical Medicine, Numer 10/7, 2021, Strona(/y) 1361, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10071361

TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation

Autorzy: Ibone Labiano, Aloña Agirre-Lizaso, Paula Olaizola, Anne Echebarria, Maider Huici-Izagirre, Irene Olaizola, Aitor Esparza-Baquer, Omar Sharif, Elizabeth Hijona, Piotr Milkiewicz, Malgorzata Milkiewicz, Francisco González-Romero, Patricia Aspichueta , Maria J Monte, Jose J G Marin, Mihael Vucur, Tom Luedde, Marco Marzioni, Derek A Mann , Luis Bujanda , Pedro M Rodrigues, Jesus M Banales, Maria J
Opublikowane w: Journal of Hepatology, Numer 77/4, 2022, Strona(/y) 991-1004, ISSN 1600-0641
Wydawca: Elsevier
DOI: 10.1016/j.jhep.2022.05.044

Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

Autorzy: Amelie Echle, Heike Irmgard Grabsch, Philip Quirke, Piet A. van den Brandt, Nicholas P. West, Gordon G.A. Hutchins, Lara R. Heij, Xiuxiang Tan, Susan D. Richman, Jeremias Krause, Elizabeth Alwers, Josien Jenniskens, Kelly Offermans, Richard Gray, Hermann Brenner, Jenny Chang-Claude, Christian Trautwein, Alexander T. Pearson, Peter Boor, Tom Luedde, Nadine Therese Gaisa, Michael Hoffmeister, Jakob
Opublikowane w: Gastroenterology, Numer 159/4, 2020, Strona(/y) 1406-1416.e11, ISSN 0016-5085
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.06.021

Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma

Autorzy: Christoph Roderburg, Sven H Loosen, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sophia M Schmitz, Mihael Vucur, Mark Luedde, Pia Paffenholz, Frank Tacke, Christian Trautwein, Tom F Ulmer, Ulf Peter Neumann, Tom Luedde
Opublikowane w: International Journal of Molecular Sciences, Numer 22/12, 2021, Strona(/y) 6569, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22126569

A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

Autorzy: Maria Feoktistova, Roman Makarov, Sihem Brenji, Anne T. Schneider, Guido J. Hooiveld, Tom Luedde, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Opublikowane w: Cells, Numer 9/2, 2020, Strona(/y) 351, ISSN 2073-4409
Wydawca: MDPI (Multidisciplinary Digital Publishing Institute)
DOI: 10.3390/cells9020351

Clinical determinants of hospital mortality in liver failure: a comprehensive analysis of 62,717 patients

Autorzy: Tom Luedde; Sven H. Loosen; Tobias Essing; Hans Bock; Björn Wieland; Georg Fluegen; Jan Bednarsch; Johannes G. Bode; Ulf P. Neumann; Christoph Roderburg
Opublikowane w: Zeitschrift für Gastroenterologie, 2023, ISSN 1439-7803
Wydawca: Georg Thieme Verlag
DOI: 10.1055/a-2016-9061

Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer

Autorzy: Sven H. Loosen, Annemarie Breuer, Frank Tacke, Jakob N. Kather, Joao Gorgulho, Patrick H. Alizai, Jan Bednarsch, Anjali A. Roeth, Georg Lurje, Sophia M. Schmitz, Jonathan F. Brozat, Pia Paffenholz, Mihael Vucur, Thomas Ritz, Alexander Koch, Christian Trautwein, Tom F. Ulmer, Christoph Roderburg, Thomas Longerich, Ulf P. Neumann, Tom Luedde
Opublikowane w: JHEP Reports, Numer 2/2, 2020, Strona(/y) 100080, ISSN 2589-5559
Wydawca: Elsevier
DOI: 10.1016/j.jhepr.2020.100080

Serum levels of circulating microRNA-107 are elevated in patients with early-stage HCC

Autorzy: Sven H. Loosen, Mirco Castoldi, Markus S. Jördens, Sanchary Roy, Mihael Vucur, Jennis Kandler, Linda Hammerich, Raphael Mohr, Frank Tacke, Tom F. Ulmer, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Opublikowane w: PLOS ONE, Numer 16/3, 2021, Strona(/y) e0247917, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0247917

Elevated Serum Levels of CCL23 Are Associated with Poor Outcome after Resection of Biliary Tract Cancer

Autorzy: Christoph Roderburg, Simon Labuhn, Jan Bednarsch, Sven A Lang, Anne T Schneider, Linda Hammerich, Mihael Vucur, Tom F Ulmer, Ulf P Neumann, Tom Luedde, Sven H Loosen
Opublikowane w: Mediators of Inflammation, 2022, Strona(/y) 6195004, ISSN 0962-9351
Wydawca: Hindawi Publishing Corporation
DOI: 10.1155/2022/6195004

High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma

Autorzy: Sven H Loosen, Frank Tacke, Niklas Püthe, Marcel Binneboesel, Georg Wiltberger, Patrick H Alizai, Jakob N Kather, Pia Paffenholz, Thomas Ritz, Alexander Koch, Frank Bergmann, Christian Trautwein, Thomas Longerich, Christoph Roderburg, Ulf P Neumann, Tom Luedde
Opublikowane w: Carcinogenesis, Numer 40/8, 2019, Strona(/y) 947-955, ISSN 0143-3334
Wydawca: Oxford University Press
DOI: 10.1093/carcin/bgz033