How cellular suicide programmes control phase transitions in fatty liver disease and liver cancer

Informazioni relative al progetto

PhaseControl

ID dell’accordo di sovvenzione: 771083

DOI

10.3030/771083

Progetto chiuso

Data della firma CE 15 Maggio 2018

Data di avvio 1 Novembre 2018

Data di completamento 30 Aprile 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 997 840,00

Contributo UE

€ 1 997 840,00

Coordinato da

HEINRICH-HEINE-UNIVERSITAET DUESSELDORF
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (40)

Differential role of chronic liver diseases on the incidence of cancer: a longitudinal analysis among 248,224 outpatients in Germany

Autori: Sven H Loosen, David Schöler, Mark Luedde, Johannes Eschrich, Tom Luedde, Karel Kostev, Christoph Roderburg
Pubblicato in: Journal of Cancer Research and Clinical Oncology, 2022, ISSN 0171-5216
Editore: Springer Verlag
DOI: 10.1007/s00432-022-04198-5

The association between the body height and cardiovascular diseases: a retrospective analysis of 657,310 outpatients in Germany

Autori: Sarah Krieg, Karel Kostev, Mark Luedde, Andreas Krieg, Tom Luedde, Christoph Roderburg, Sven H Loosen
Pubblicato in: European Journal of Medical Research, Numero 27/1, 2022, Pagina/e 240, ISSN 0949-2321
Editore: Holzapfel Verlag GmbH
DOI: 10.1186/s40001-022-00881-y

Deep learning in cancer pathology: a new generation of clinical biomarkers

Autori: Amelie Echle, Niklas Timon Rindtorff, Titus Josef Brinker, Tom Luedde, Alexander Thomas Pearson, Jakob Nikolas Kather
Pubblicato in: British Journal of Cancer, Numero 124, 2023, Pagina/e 686-696, ISSN 0007-0920
Editore: Nature Publishing Group
DOI: 10.1038/s41416-020-01122-x

Circulating Osteopontin Levels and Outcomes in Patients Hospitalized for COVID-19

Autori: Salim S Hayek, Christoph Roderburg, Pennelope Blakely, Christopher Launius, Jesper Eugen-Olsen, Frank Tacke, Sofia Ktena, Verena Keitel, Mark Luedde, Evangelos J Giamarellos-Bourboulis, Tom Luedde, Sven H Loosen
Pubblicato in: Journal of Clinical Medicine, Numero 10/17, 2021, Pagina/e 3907, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10173907

An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration

Autori: Koppe, Reisinger, Wehr, Vucur, Trautwein, Tacke, Heikenwalder, Luedde
Pubblicato in: Cancers, Numero 11/7, 2019, Pagina/e 999, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11070999

An Elevated FIB-4 Score Is Associated with an Increased Incidence of Depression among Outpatients in Germany

Autori: David Schöler; Karel Kostev; Münevver Demir; Mark Luedde; Marcel Konrad; Tom Luedde; Christoph Roderburg; Sven H. Loosen
Pubblicato in: Journal of Clinical Medicine, Numero 11/8, 2022, Pagina/e 2214, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11082214

Hospital Mortality and Current Trends in Liver Transplantation in Germany — a Systematic Analysis of Standardized Hospital Discharge Data, 2008–2017

Autori: Sven H Loosen, Hans H Bock, Martin Hellmich, Wolfram T. Knoefel, Christian Trautwein, Verena Keitel, Johannes G. Bode, Ulf P. Neumann, Tom Luedde
Pubblicato in: Deutsches Ärzteblatt International, Numero 118/29-30, 2021, Pagina/e 497-502, ISSN 1866-0452
Editore: Deutscher Arzte-Verlag
DOI: 10.3238/arztebl.m2021.0210

Golgi Protein 73 (GP73) Serum Levels Predict Outcome after Resection of Biliary Tract Cancer

Autori: Sven H Loosen, Justus Halpaap, Simon Labuhn, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sven A Lang, Mihael Vucur, Jakob N Kather, Wolfram T Knoefel, Tom F Ulmer, Ulf P Neumann, Christoph Roderburg, Tom Luedde
Pubblicato in: Cancers, Numero 14/18, 2022, Pagina/e 4428, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14184428

Perception of the 2020 SARS-CoV-2 pandemic among medical professionals in Germany: results from a nationwide online survey

Autori: Pia Paffenholz, Arne Peine, Martin Hellmich, Stella V. Paffenholz, Lukas Martin, Mark Luedde, Miriam Haverkamp, Christoph Roderburg, Gernot Marx, Axel Heidenreich, Christian Trautwein, Tom Luedde, Sven H. Loosen
Pubblicato in: Emerging Microbes & Infections, Numero 9/1, 2020, Pagina/e 1590-1599, ISSN 2222-1751
Editore: Nature Publishing Group
DOI: 10.1080/22221751.2020.1785951

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

Autori: Benjamin Rolles, Joao Gorgulho, Mareike Tometten, Christoph Roderburg, Margherita Vieri, Anne Abels, Mihael Vucur, Felix Heymann, Frank Tacke, Tim H Brümmendorf, Tom Luedde, Fabian Beier, Sven H Loosen
Pubblicato in: Frontiers in Oncology, Numero 11, 2021, Pagina/e 729207, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.729207

Factors Associated with Non-Severe Adverse Reactions after Vaccination against SARS-CoV-2: A Cohort Study of 908,869 Outpatient Vaccinations in Germany

Autori: Sven H Loosen, Jens Bohlken, Kerstin Weber, Marcel Konrad, Tom Luedde, Christoph Roderburg, Karel Kostev
Pubblicato in: Vaccines, Numero 10/4, 2022, Pagina/e 566, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10040566

A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development

Autori: Anne T. Schneider, Christiane Koppe, Emilie Crouchet, Aristeidis Papargyriou, Michael T. Singer, Veronika Büttner, Leonie Keysberg, Marta Szydlowska, Frank Jühling, Julien Moehlin, Min-Chun Chen, Valentina Leone, Sebastian Mueller, Thorsten Neuß, Mirco Castoldi, Marina Lesina, Frank Bergmann, Thilo Hackert, Katja Steiger, Wolfram T. Knoefel, Alex Zaufel, Jakob N. Kather, Irene Esposito, Matthia
Pubblicato in: Nature Communications, Numero 16, 2025, Pagina/e 1765, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-56493-7

Obesity and lipid metabolism disorders determine the risk for development of long COVID syndrome: a cross-sectional study from 50,402 COVID-19 patients

Autori: Sven H Loosen, Björn-Erik Ole Jensen, Christian Tanislav, Tom Luedde, Christoph Roderburg, Karel Kostev
Pubblicato in: Infection, 2022, Pagina/e 1-6, ISSN 0300-8126
Editore: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s15010-022-01784-0

Pan-cancer image-based detection of clinically actionable genetic alterations

Autori: Jakob Nikolas Kather, Lara R. Heij, Heike I. Grabsch, Chiara Loeffler, Amelie Echle, Hannah Sophie Muti, Jeremias Krause, Jan M. Niehues, Kai A. J. Sommer, Peter Bankhead, Loes F. S. Kooreman, Jefree J. Schulte, Nicole A. Cipriani, Roman D. Buelow, Peter Boor, Nadina Ortiz-Brüchle, Andrew M. Hanby, Valerie Speirs, Sara Kochanny, Akash Patnaik, Andrew Srisuwananukorn, Hermann Brenner, Michael Hoff
Pubblicato in: Nature Cancer, Numero 1/8, 2020, Pagina/e 789-799, ISSN 2662-1347
Editore: Springer Nature
DOI: 10.1038/s43018-020-0087-6

Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy

Autori: Joao Gorgulho, Sven H. Loosen, Ramsha Masood, Franziska Giehren, Francesca Pagani, Gustav Buescher, Lorenz Kocheise, Vincent Joerg, Constantin Schmidt, Kornelius Schulze, Christoph Roderburg, Eva Kinkel, Britta Fritzsche, Simon Wehmeyer, Benjamin Schmidt, Paul Kachel, Christina Rolling, Julian Götze, Alina Busch, Marianne Sinn, Thais Pereira-Veiga, Harriet Wikman, Maria Geffken, Sven Peine, Urte
Pubblicato in: Journal of Experimental & Clinical Cancer Research, Numero 43, 2024, Pagina/e 298, ISSN 1756-9966
Editore: BMC
DOI: 10.1186/s13046-024-03215-4

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Autori: Jakob Nikolas Kather, Alexander T. Pearson, Niels Halama, Dirk Jäger, Jeremias Krause, Sven H. Loosen, Alexander Marx, Peter Boor, Frank Tacke, Ulf Peter Neumann, Heike I. Grabsch, Takaki Yoshikawa, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Christian Trautwein, Tom Luedde
Pubblicato in: Nature Medicine, Numero 25/7, 2019, Pagina/e 1054-1056, ISSN 1078-8956
Editore: Nature Publishing Group
DOI: 10.1038/s41591-019-0462-y

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

Autori: Ahmed Ghallab, Reham Hassan, Ute Hofmann, Adrian Friebel, Zaynab Hobloss, Lisa Brackhagen, Brigitte Begher-Tibbe, Maiju Myllys, Joerg Reinders, Nina Overbeck, Selahaddin Sezgin, Sebastian Zühlke, Abdel-Latif Seddek, Walaa Murad, Tim Brecklinghaus, Franziska Kappenberg, Jörg Rahnenführer, Daniela González, Christopher Goldring, Ian M Copple, Rosemarie Marchan, Thomas Longerich, Mihael Vucur, To
Pubblicato in: Journal of Hepatology, Numero 77/1, 2022, Pagina/e 71-83, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2022.01.020

Decreased Bone Mineral Density Is a Predictor of Poor Survival in Critically Ill Patients.

Autori: Maximilian Schulze-Hagen; Christoph Roderburg; Theresa H. Wirtz; Markus S. Jördens; Lukas Bündgens; Samira Abu Jhaisha; Philipp Hohlstein; Jonathan F. Brozat; Philipp Bruners; Christina Loberg; Christiane K. Kuhl; Christian Trautwein; Frank Tacke; Tom Luedde; Sven H. Loosen; Alexander Koch
Pubblicato in: Journal of Clinical Medicine, Numero 10/16, 2021, Pagina/e 3741, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10163741

JNK signaling prevents biliary cyst formation through a CASPASE-8–dependent function of RIPK1 during aging

Autori: Katrin Müller, Hanna Honcharova-Biletska, Christiane Koppe, Michèle Egger, Lap Kwan Chan, Anne T. Schneider, Lena Küsgens, Friederike Böhm, Yannick Boege, Marc E. Healy, Johannes Schmitt, Sarah Comtesse, Mirco Castoldi, Christian Preisinger, Marta Szydlowska, Enrico Focaccia, Nadine T. Gaisa, Sven H. Loosen, Simone Jörs, Frank Tacke, Christoph Roderburg, Verena Keitel, Johannes G. Bode, Peter
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 118/12, 2021, Pagina/e e2007194118, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2007194118

Soluble lymphocyte activation gene-3 (sLAG3) and CD4/CD8 ratio dynamics as predictive biomarkers in patients undergoing immune checkpoint blockade for solid malignancies

Autori: Joao Gorgulho, Christoph Roderburg, Fabian Beier, Carsten Bokemeyer, Tim H. Brümmendorf, Sven H. Loosen, Tom Luedde
Pubblicato in: British Journal of Cancer, Numero 130, 2024, Pagina/e 1013-1022, ISSN 0007-0920
Editore: Nature Publishing Group
DOI: 10.1038/s41416-023-02558-7

Non-Alcoholic Fatty Liver Disease (NAFLD) and risk of new-onset heart failure: a retrospective analysis of 173,966 patients

Autori: Christoph Roderburg, Sarah Krieg, Andreas Krieg, Sascha Vaghiri, Raphael Mohr, Marcel Konrad, Mark Luedde, Tom Luedde, Karel Kostev, Sven H. Loosen
Pubblicato in: Clinical Research in Cardiology, Numero 112, 2023, Pagina/e 1446-1453, ISSN 1861-0684
Editore: Steinkopff
DOI: 10.1007/s00392-023-02250-z

Current Trends in Inpatient Care and In-Hospital Mortality of Cholangiocarcinoma in Germany: A Systematic Analysis between 2010 and 2019

Autori: Christoph Roderburg, Tobias Essing, Linde Kehmann, Sarah Krieg, Simon Labuhn, Jennis Kandler, Tom Luedde, Sven H Loosen
Pubblicato in: Cancers, Numero 14/16, 2022, Pagina/e 4038, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14164038

Circulating levels of microRNA193a-5p predict outcome in early stage hepatocellular carcinoma

Autori: Sven H. Loosen, Theresa H. Wirtz, Sanchari Roy, Mihael Vucur, Mirco Castoldi, Anne T. Schneider, Christiane Koppe, Tom F. Ulmer, Anjali A. Roeth, Jan Bednarsch, Patrick H. Alizai, Pia Paffenholz, Münevver Demir, Christian Trautwein, Frank Tacke, Ulf P. Neumann, Christoph Roderburg, Tom Luedde
Pubblicato in: PLOS ONE, Numero 15/9, 2020, Pagina/e e0239386, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0239386

Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies

Autori: Joao Gorgulho, Christoph Roderburg, Felix Heymann, Maximilian Schulze‐Hagen, Fabian Beier, Mihael Vucur, Jakob N. Kather, Narmin Ghaffari Laleh, Frank Tacke, Tim H. Brümmendorf, Tom Luedde, Sven H. Loosen
Pubblicato in: International Journal of Cancer, Numero 149/5, 2021, Pagina/e 1189-1198, ISSN 0020-7136
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ijc.33610

Serum Levels of Kisspeptin Are Elevated in Patients with Pancreatic Cancer

Autori: Sven H. Loosen, Mark Luedde, Georg Lurje, Martina Spehlmann, Pia Paffenholz, Tom Florian Ulmer, Frank Tacke, Mihael Vucur, Christian Trautwein, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Pubblicato in: Disease Markers, Numero 2019, 2019, Pagina/e 1-8, ISSN 0278-0240
Editore: IOS Press
DOI: 10.1155/2019/5603474

The Role of Adipokines as Circulating Biomarkers in Critical Illness and Sepsis

Autori: Sven H. Loosen, Alexander Koch, Frank Tacke, Christoph Roderburg, Tom Luedde
Pubblicato in: International Journal of Molecular Sciences, Numero 20/19, 2019, Pagina/e 4820, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20194820

Sublethal necroptosis signaling promotes inflammation and liver cancer

Autori: Mihael Vucur, Ahmed Ghallab, Anne T Schneider, Arlind Adili, Mingbo Cheng, Mirco Castoldi, Michael T Singer, Veronika Büttner, Leonie S Keysberg, Lena Küsgens, Marlene Kohlhepp, Boris Görg, Suchira Gallage, Jose Efren Barragan Avila, Kristian Unger, Claus Kordes, Anne-Laure Leblond, Wiebke Albrecht, Sven H Loosen, Carolin Lohr, Markus S Jördens, Anne Babler, Sikander Hayat, David Schumacher, M
Pubblicato in: Immunity, Numero 56/7, 2023, Pagina/e 1578-1595, ISSN 1074-7613
Editore: Cell Press
DOI: 10.1016/j.immuni.2023.05.017

Serum Levels of CXCL13 Are an Independent Predictor of Survival Following Resection of Biliary Tract Cancer

Autori: Sven H Loosen, Tom F Ulmer, Simon Labuhn, Jan Bednarsch, Sven A Lang, Patrick H Alizai, Anne T Schneider, Mihael Vucur, Ulf P Neumann, Tom Luedde, Christoph Roderburg
Pubblicato in: Cancers, Numero 14/14, 2022, Pagina/e 4073, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14174073

Adult Body Height Is Associated with the Risk of Type 2 but Not Type 1 Diabetes Mellitus: A Retrospective Cohort Study of 783,029 Individuals in Germany

Autori: Sven H Loosen, Sarah Krieg, Andreas Krieg, Tom Luedde, Karel Kostev, Christoph Roderburg
Pubblicato in: Journal of Clinical Medicine, Numero 12/6, 2023, Pagina/e 2199, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm12062199

Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autori: Sven H. Loosen, Joao Gorgulho, Markus S. Jördens, Maximilian Schulze-Hagen, Fabian Beier, Mihael Vucur, Anne T. Schneider, Christiane Koppe, Alexander Mertens, Jakob N. Kather, Frank Tacke, Verena Keitel, Tim H. Brümmendorf, Christoph Roderburg, Tom Luedde
Pubblicato in: Frontiers in Oncology, Numero 11, 2021, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.646883

Progressive Sarcopenia Correlates with Poor Response and Outcome to Immune Checkpoint Inhibitor Therapy

Autori: Sven H. Loosen, Vincent van den Bosch, Joao Gorgulho, Maximilian Schulze-Hagen, Jennis Kandler, Markus S. Jördens, Frank Tacke, Christina Loberg, Gerald Antoch, Tim Brümmendorf, Ulf P. Neumann, Christiane Kuhl, Tom Luedde, Christoph Roderburg
Pubblicato in: Journal of Clinical Medicine, Numero 10/7, 2021, Pagina/e 1361, ISSN 2077-0383
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10071361

TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation

Autori: Ibone Labiano, Aloña Agirre-Lizaso, Paula Olaizola, Anne Echebarria, Maider Huici-Izagirre, Irene Olaizola, Aitor Esparza-Baquer, Omar Sharif, Elizabeth Hijona, Piotr Milkiewicz, Malgorzata Milkiewicz, Francisco González-Romero, Patricia Aspichueta , Maria J Monte, Jose J G Marin, Mihael Vucur, Tom Luedde, Marco Marzioni, Derek A Mann , Luis Bujanda , Pedro M Rodrigues, Jesus M Banales, Maria J
Pubblicato in: Journal of Hepatology, Numero 77/4, 2022, Pagina/e 991-1004, ISSN 1600-0641
Editore: Elsevier
DOI: 10.1016/j.jhep.2022.05.044

Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning

Autori: Amelie Echle, Heike Irmgard Grabsch, Philip Quirke, Piet A. van den Brandt, Nicholas P. West, Gordon G.A. Hutchins, Lara R. Heij, Xiuxiang Tan, Susan D. Richman, Jeremias Krause, Elizabeth Alwers, Josien Jenniskens, Kelly Offermans, Richard Gray, Hermann Brenner, Jenny Chang-Claude, Christian Trautwein, Alexander T. Pearson, Peter Boor, Tom Luedde, Nadine Therese Gaisa, Michael Hoffmeister, Jakob
Pubblicato in: Gastroenterology, Numero 159/4, 2020, Pagina/e 1406-1416.e11, ISSN 0016-5085
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2020.06.021

Levels of Circulating PD-L1 Are Decreased in Patients with Resectable Cholangiocarcinoma

Autori: Christoph Roderburg, Sven H Loosen, Jan Bednarsch, Patrick H Alizai, Anjali A Roeth, Sophia M Schmitz, Mihael Vucur, Mark Luedde, Pia Paffenholz, Frank Tacke, Christian Trautwein, Tom F Ulmer, Ulf Peter Neumann, Tom Luedde
Pubblicato in: International Journal of Molecular Sciences, Numero 22/12, 2021, Pagina/e 6569, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22126569

A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

Autori: Maria Feoktistova, Roman Makarov, Sihem Brenji, Anne T. Schneider, Guido J. Hooiveld, Tom Luedde, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Pubblicato in: Cells, Numero 9/2, 2020, Pagina/e 351, ISSN 2073-4409
Editore: MDPI (Multidisciplinary Digital Publishing Institute)
DOI: 10.3390/cells9020351

Clinical determinants of hospital mortality in liver failure: a comprehensive analysis of 62,717 patients

Autori: Tom Luedde; Sven H. Loosen; Tobias Essing; Hans Bock; Björn Wieland; Georg Fluegen; Jan Bednarsch; Johannes G. Bode; Ulf P. Neumann; Christoph Roderburg
Pubblicato in: Zeitschrift für Gastroenterologie, 2023, ISSN 1439-7803
Editore: Georg Thieme Verlag
DOI: 10.1055/a-2016-9061

Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer

Autori: Sven H. Loosen, Annemarie Breuer, Frank Tacke, Jakob N. Kather, Joao Gorgulho, Patrick H. Alizai, Jan Bednarsch, Anjali A. Roeth, Georg Lurje, Sophia M. Schmitz, Jonathan F. Brozat, Pia Paffenholz, Mihael Vucur, Thomas Ritz, Alexander Koch, Christian Trautwein, Tom F. Ulmer, Christoph Roderburg, Thomas Longerich, Ulf P. Neumann, Tom Luedde
Pubblicato in: JHEP Reports, Numero 2/2, 2020, Pagina/e 100080, ISSN 2589-5559
Editore: Elsevier
DOI: 10.1016/j.jhepr.2020.100080

Serum levels of circulating microRNA-107 are elevated in patients with early-stage HCC

Autori: Sven H. Loosen, Mirco Castoldi, Markus S. Jördens, Sanchary Roy, Mihael Vucur, Jennis Kandler, Linda Hammerich, Raphael Mohr, Frank Tacke, Tom F. Ulmer, Ulf P. Neumann, Tom Luedde, Christoph Roderburg
Pubblicato in: PLOS ONE, Numero 16/3, 2021, Pagina/e e0247917, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0247917

Elevated Serum Levels of CCL23 Are Associated with Poor Outcome after Resection of Biliary Tract Cancer

Autori: Christoph Roderburg, Simon Labuhn, Jan Bednarsch, Sven A Lang, Anne T Schneider, Linda Hammerich, Mihael Vucur, Tom F Ulmer, Ulf P Neumann, Tom Luedde, Sven H Loosen
Pubblicato in: Mediators of Inflammation, 2022, Pagina/e 6195004, ISSN 0962-9351
Editore: Hindawi Publishing Corporation
DOI: 10.1155/2022/6195004

High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma

Autori: Sven H Loosen, Frank Tacke, Niklas Püthe, Marcel Binneboesel, Georg Wiltberger, Patrick H Alizai, Jakob N Kather, Pia Paffenholz, Thomas Ritz, Alexander Koch, Frank Bergmann, Christian Trautwein, Thomas Longerich, Christoph Roderburg, Ulf P Neumann, Tom Luedde
Pubblicato in: Carcinogenesis, Numero 40/8, 2019, Pagina/e 947-955, ISSN 0143-3334
Editore: Oxford University Press
DOI: 10.1093/carcin/bgz033