Spectroscopy in cells with tailored in-vivo labelling strategies and multiply addressable nano-structural probes

Información del proyecto

SPICE

Identificador del acuerdo de subvención: 772027

DOI

10.3030/772027

Proyecto cerrado

Fecha de la firma de la CE 18 Abril 2018

Fecha de inicio 1 Junio 2018

Fecha de finalización 30 Noviembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 988 697,50

Aportación de la UE

€ 1 988 697,50

Coordinado por

UNIVERSITAT KONSTANZ
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (22)

Magnesium induced structural reorganization in the active site of adenylate kinase

Autores: Kwangho Nam, Abdul Raafik Arattu Thodika, Sonja Tischlik, Chanrith Phoeurk, Tamás Milán Nagy, Léon Schierholz, Jörgen Ådén, Per Rogne, Malte Drescher, A. Elisabeth Sauer-Eriksson, Magnus Wolf-Watz
Publicado en: Science Advances, Edición 10, 2024, ISSN 2375-2548
Editor: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.ado5504

Intracellular Protein–Lipid Interactions Studied by Rapid-Scan Electron Paramagnetic Resonance Spectroscopy

Autores: Theresa S. Braun, Juliane Stehle, Sylwia Kacprzak, Patrick Carl, Peter Höfer, Vinod Subramaniam, Malte Drescher
Publicado en: The Journal of Physical Chemistry Letters, Edición 12, 2023, Página(s) 2471-2475, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.1021/acs.jpclett.0c03583

Dance with spins: site-directed spin labeling coupled to electron paramagnetic resonance spectroscopy directly inside cells

Autores: Annalisa Pierro, Malte Drescher
Publicado en: Chemical Communications, Edición 59, 2024, Página(s) 1274-1284, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc05907j

Insights into Enzymatic Catalysis from Binding and Hydrolysis of Diadenosine Tetraphosphate by <i>E</i>. <i>coli</i> Adenylate Kinase

Autores: Sonja Tischlik, Melanie Oelker, Per Rogne, A. Elisabeth Sauer-Eriksson, Malte Drescher, Magnus Wolf-Watz
Publicado en: Biochemistry, Edición 62, 2023, Página(s) 2238-2243, ISSN 0006-2960
Editor: American Chemical Society
DOI: 10.1021/acs.biochem.3c00189

Increasing the Modulation Depth of Gd^III-Based Pulsed Dipolar EPR Spectroscopy (PDS) with Porphyrin–Gd^III Laser-Induced Magnetic Dipole Spectroscopy

Autores: Andreas Scherer, Xuemei Yao, Mian Qi, Max Wiedmaier, Adelheid Godt, Malte Drescher
Publicado en: The Journal of Physical Chemistry Letters, Edición 13, 2023, Página(s) 10958-10964, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.1021/acs.jpclett.2c02138

Combining Site-Directed Spin Labeling in Vivo and In-Cell EPR Distance Determination

Autores: Pia Widder, Julian Schuck, Daniel Summerer, Malte Drescher
Publicado en: PCCP, 2021, ISSN 1463-9076
Editor: Royal Society of Chemistry
DOI: 10.26434/chemrxiv.9746222.v1

Background removal from rapid-scan EPR spectra of nitroxide-based spin labels by minimizing non-quadratic cost functions

Autores: Florian Johannsen, Malte Drescher
Publicado en: Journal of Magnetic Resonance Open, Edición 16-17, 2023, Página(s) 100121, ISSN 2666-4410
Editor: Elsevier BV
DOI: 10.1016/j.jmro.2023.100121

Optimising broadband pulses for DEER depends on concentration and distance range of interest

Autores: Andreas Scherer, Sonja Tischlik, Sabrina Weickert, Valentin Wittmann, Malte Drescher
Publicado en: Magnetic Resonance, Edición 1, 2025, Página(s) 59-74, ISSN 2699-0016
Editor: Copernicus GmbH
DOI: 10.5194/mr-1-59-2020

Isoindoline‐Based Nitroxides as Bioresistant Spin Labels for Protein Labeling through Cysteines and Alkyne‐Bearing Noncanonical Amino Acids

Autores: Theresa Sophie Braun, Pia Widder, Uwe Osswald, Lina Groß, Lara Williams, Moritz Schmidt, Irina Helmle, Daniel Summerer, Malte Drescher
Publicado en: ChemBioChem, Edición 21, 2023, Página(s) 958-962, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201900537

The molecular mechanism of Hsp90-induced oligomerization of Tau

Autores: Sabrina Weickert, Magdalena Wawrzyniuk, Laura John, Stefan G. D. Rüdiger, Malte Drescher
Publicado en: Science Advances, 2019, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1101/614289

Double Nitroxide Labeling by Copper-Catalyzed Azide–Alkyne Cycloadditions with Noncanonical Amino Acids for Electron Paramagnetic Resonance Spectroscopy

Autores: Pia Widder, Frederic Berner, Daniel Summerer, Malte Drescher
Publicado en: ACS Chemical Biology, Edición 14/5, 2019, Página(s) 839-844, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.8b01111

Gd(III)–Gd(III) Relaxation-Induced Dipolar Modulation Enhancement for In-Cell Electron Paramagnetic Resonance Distance Determination

Autores: Mykhailo Azarkh, Anna Bieber, Mian Qi, Jörg W. A. Fischer, Maxim Yulikov, Adelheid Godt, Malte Drescher
Publicado en: The Journal of Physical Chemistry Letters, Edición 10/7, 2019, Página(s) 1477-1481, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.1021/acs.jpclett.9b00340

Protein Spin Labeling with a Photocaged Nitroxide Using Diels–Alder Chemistry

Autores: Anandi Kugele, Bjarne Silkenath, Jakob Langer, Valentin Wittmann, Malte Drescher
Publicado en: ChemBioChem, 2019, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201900318

Site-directed spin labelling of proteins by Suzuki–Miyaura coupling via a genetically encoded aryliodide amino acid

Autores: Anandi Kugele, Theresa Sophie Braun, Pia Widder, Lara Williams, Moritz Johannes Schmidt, Daniel Summerer, Malte Drescher
Publicado en: Chemical Communications, Edición 55/13, 2019, Página(s) 1923-1926, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c8cc09325c

Expanding the Genetic Code for Site-Directed Spin-Labeling

Autores: Theresa Braun, Malte Drescher, Daniel Summerer
Publicado en: International Journal of Molecular Sciences, Edición 20/2, 2019, Página(s) 373, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20020373

Light-induced dipolar spectroscopy – A quantitative comparison between LiDEER and LaserIMD

Autores: Anna Bieber, Dennis Bücker, Malte Drescher
Publicado en: Journal of Magnetic Resonance, Edición 296, 2018, Página(s) 29-35, ISSN 1090-7807
Editor: Academic Press
DOI: 10.1016/j.jmr.2018.08.006

Site-directed attachment of photoexcitable spin labels for light-induced pulsed dipolar spectroscopy

Autores: Lara Williams, Sonja Tischlik, Andreas Scherer, Jörg Wolfram Anselm Fischer, Malte Drescher
Publicado en: Chemical Communications, Edición 56, 2024, Página(s) 14669-14672, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d0cc03101a

Rapid Scan Electron Paramagnetic Resonance Spectroscopy Is a Suitable Tool to Study Intermolecular Interactions of Intrinsically Disordered Protein

Autores: Jessica Dröden, Malte Drescher
Publicado en: Biology, Edición 12, 2024, Página(s) 79, ISSN 2079-7737
Editor: MDPI AG
DOI: 10.3390/biology12010079

<i>In situ</i> EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code

Autores: Anandi Kugele, Sophie Ketter, Bjarne Silkenath, Valentin Wittmann, Benesh Joseph, Malte Drescher
Publicado en: Chemical Communications, Edición 57, 2024, Página(s) 12980-12983, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d1cc04612h

Arabidopsis CaLB1 undergoes phase separation with the ESCRT protein ALIX and modulates autophagosome maturation

Autores: Niccolò Mosesso, Niharika Savant Lerner, Tobias Bläske, Felix Groh, Shane Maguire, Marie Laura Niedermeier, Eliane Landwehr, Karin Vogel, Konstanze Meergans, Marie-Kristin Nagel, Malte Drescher, Florian Stengel, Karin Hauser, Erika Isono
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-49485-6

The effect of the zero-field splitting in light-induced pulsed dipolar electron paramagnetic resonance (EPR) spectroscopy

Autores: Andreas Scherer, Berk Yildirim, Malte Drescher
Publicado en: Magnetic Resonance, Edición 4, 2025, Página(s) 27-46, ISSN 2699-0016
Editor: Copernicus GmbH
DOI: 10.5194/mr-4-27-2023

Real-time Monitoring of Photoinduced pH-jumps by In Situ Rapid-scan EPR Spectroscopy

Autores: Florian Johannsen, Lara Williams, Man Him Chak, Malte Drescher
Publicado en: Journal of Physical Chemistry Letters, 2023, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.26434/chemrxiv-2023-x6d2t

Other (1)

Spin labelling via metabolic glycoengineering for studying post-translational protein modification by electron paramagnetic resonance spectroscopy

Autores: Anna Rubailo, Valentin Wittmann, Malte Drescher
Publicado en: Chemrxiv, 2022
Editor: chemrxiv
DOI: 10.26434/chemrxiv-2022-j2mc1-v2