The ubiquitin system in RAS-driven disease

Publicaciones

Cracking the Monoubiquitin Code of Genetic Diseases

Autores: Raj Nayan Sewduth, Maria Francesca Baietti, Anna A. Sablina
Publicado en: International Journal of Molecular Sciences, Edición 21/9, 2020, Página(s) 3036, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21093036

The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking

Autores: Raj Nayan Sewduth, Silvia Pandolfi, Mikhail Steklov, Aidana Sheryazdanova, Peihua Zhao, Nathan Criem, Maria F. Baietti, Benoit Lechat, Rozeen Quarck, Francis Impens, Anna A. Sablina
Publicado en: Circulation Research, Edición 126/10, 2020, Página(s) 1379-1393, ISSN 0009-7330
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315730

Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development.

Autores: Paul Najm; Peihua Zhao; Mikhail Steklov; Raj Nayan Sewduth; Maria Francesca Baietti; Silvia Pandolfi; Nathan Criem; Benoit Lechat; Teresa Mendes Maia; Delphi Van Haver; Nikky Corthout; Sven Eyckerman; Francis Impens; Anna Sablina
Publicado en: Cancer Research, 2021, ISSN 0008-5472
Editor: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-20-3669

Targeted STAT1 therapy for LZTR1-driven peripheral nerve sheath tumor

Autores: Tonci Ivanisevic, Mikhail Steklov, Benoit Lechat, Christopher Cawthorne, Willy Gsell, Greetje Vande Velde, Christophe Deroose, Koen Van Laere, Uwe Himmelreich, Raj N Sewduth, Anna A Sablina
Publicado en: Cancer Communications, 2023, ISSN 2523-3548
Editor: Wiley Online Library
DOI: 10.1002/cac2.12490

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

Autores: M. Steklov, S. Pandolfi, M. F. Baietti, A. Batiuk, P. Carai, P. Najm, M. Zhang, H. Jang, F. Renzi, Y. Cai, L. Abbasi Asbagh, T. Pastor, M. De Troyer, M. Simicek, E. Radaelli, H. Brems, E. Legius, J. Tavernier, K. Gevaert, F. Impens, L. Messiaen, R. Nussinov, S. Heymans, S. Eyckerman, A. A. Sablina
Publicado en: Science, Edición 362/6419, 2018, Página(s) 1177-1182, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.aap7607

Spatial mechano-signaling regulation of GTPases through non-degradative ubiquitination

Autores: RN Sewduth, P Carai, T Ivanisevic, M Zhang, H Jang, B Lechat, D Van Haver, F Impens, R Nussinov, EA Jones, AA Sablina
Publicado en: Advanced Science, 2023, ISSN 2198-3844
Editor: Wiley Online Library
DOI: 10.1002/advs.202303367

The regulation of the protein interaction network by monoubiquitination

Autores: Wout Magits; Anna A. Sablina
Publicado en: Current Opinion in Structural Biology, 2022, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2022.102333

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