The ubiquitin system in RAS-driven disease

Pubblicazioni

Cracking the Monoubiquitin Code of Genetic Diseases

Autori: Raj Nayan Sewduth, Maria Francesca Baietti, Anna A. Sablina
Pubblicato in: International Journal of Molecular Sciences, Numero 21/9, 2020, Pagina/e 3036, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21093036

The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking

Autori: Raj Nayan Sewduth, Silvia Pandolfi, Mikhail Steklov, Aidana Sheryazdanova, Peihua Zhao, Nathan Criem, Maria F. Baietti, Benoit Lechat, Rozeen Quarck, Francis Impens, Anna A. Sablina
Pubblicato in: Circulation Research, Numero 126/10, 2020, Pagina/e 1379-1393, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315730

Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development.

Autori: Paul Najm; Peihua Zhao; Mikhail Steklov; Raj Nayan Sewduth; Maria Francesca Baietti; Silvia Pandolfi; Nathan Criem; Benoit Lechat; Teresa Mendes Maia; Delphi Van Haver; Nikky Corthout; Sven Eyckerman; Francis Impens; Anna Sablina
Pubblicato in: Cancer Research, 2021, ISSN 0008-5472
Editore: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-20-3669

Targeted STAT1 therapy for LZTR1-driven peripheral nerve sheath tumor

Autori: Tonci Ivanisevic, Mikhail Steklov, Benoit Lechat, Christopher Cawthorne, Willy Gsell, Greetje Vande Velde, Christophe Deroose, Koen Van Laere, Uwe Himmelreich, Raj N Sewduth, Anna A Sablina
Pubblicato in: Cancer Communications, 2023, ISSN 2523-3548
Editore: Wiley Online Library
DOI: 10.1002/cac2.12490

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

Autori: M. Steklov, S. Pandolfi, M. F. Baietti, A. Batiuk, P. Carai, P. Najm, M. Zhang, H. Jang, F. Renzi, Y. Cai, L. Abbasi Asbagh, T. Pastor, M. De Troyer, M. Simicek, E. Radaelli, H. Brems, E. Legius, J. Tavernier, K. Gevaert, F. Impens, L. Messiaen, R. Nussinov, S. Heymans, S. Eyckerman, A. A. Sablina
Pubblicato in: Science, Numero 362/6419, 2018, Pagina/e 1177-1182, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.aap7607

Spatial mechano-signaling regulation of GTPases through non-degradative ubiquitination

Autori: RN Sewduth, P Carai, T Ivanisevic, M Zhang, H Jang, B Lechat, D Van Haver, F Impens, R Nussinov, EA Jones, AA Sablina
Pubblicato in: Advanced Science, 2023, ISSN 2198-3844
Editore: Wiley Online Library
DOI: 10.1002/advs.202303367

The regulation of the protein interaction network by monoubiquitination

Autori: Wout Magits; Anna A. Sablina
Pubblicato in: Current Opinion in Structural Biology, 2022, ISSN 0959-440X
Editore: Elsevier BV
DOI: 10.1016/j.sbi.2022.102333

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