Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Established network organisation and management structure
Annual gender equality monitoring

Publications

The Anti-Tumor Effect of Lactococcus lactis Bacteria-Secreting Human Soluble TRAIL Can Be Enhanced by Metformin Both In Vitro and In Vivo in a Mouse Model of Human Colorectal Cancer

Author(s): Katarzyna Kaczmarek, Jerzy Więckiewicz, Kazimierz Węglarczyk, Maciej Siedlar, Jarek Baran
Published in: Cancers, Issue 13/12, 2021, Page(s) 3004, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13123004

Chitin and Chitosans: Characteristics, Eco-Friendly Processes, and Applications in Cosmetic Science

Author(s): Cristina Casadidio, Dolores Vargas Peregrina, Maria Rosa Gigliobianco, Siyuan Deng, Roberta Censi, Piera Di Martino
Published in: Marine Drugs, Issue 17/6, 2019, Page(s) 369, ISSN 1660-3397
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md17060369

Zinc-Phthalocyanine-Loaded Extracellular Vesicles Increase Efficacy and Selectivity of Photodynamic Therapy in Co-Culture and Preclinical Models of Colon Cancer.

Author(s): Pablo Lara, Ruben V. Huis in ‘t Veld,Carla Jorquera-Cordero, Alan B. Chan,Ferry Ossendorp andLuis J. Cruz
Published in: Farmaceutics, Issue 20794991, 2021, ISSN 2079-4991
Publisher: MPDI
DOI: 10.3390/pharmaceutics13101547

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Author(s): Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle
Published in: Cancer Gene Therapy, 2020, ISSN 0929-1903
Publisher: Nature Publishing Group
DOI: 10.1038/s41417-020-00224-1

Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment

Author(s): Yang Hao, Chih Kit Chung, Zili Gu, Timo Schomann, Xiaoxu Dong, Ruben V Huis In 't Veld, Marcel G M Camps, Peter Ten Dijke, Ferry A Ossendorp, Luis J Cruz
Published in: Molecular biomedicine, 2022, ISSN 2662-8651
Publisher: Singapore : Springer Singapore, [2020]
DOI: 10.1186/s43556-022-00086-z

Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice

Author(s): Natasa Gaspar, Joel R. Walker, Giorgia Zambito, Kranthi Marella-Panth, Clemens Lowik, Thomas A. Kirkland, Laura Mezzanotte
Published in: Journal of Photochemistry and Photobiology B: Biology, Issue 216, 2021, Page(s) 112128, ISSN 1011-1344
Publisher: Elsevier BV
DOI: 10.1016/j.jphotobiol.2021.112128

Liposome-Based Drug Delivery Systems in Cancer Immunotherapy

Author(s): Zili Gu, Candido G. Da Silva, Koen Van der Maaden, Ferry Ossendorp, Luis J. Cruz
Published in: Pharmaceutics, Issue 12/11, 2020, Page(s) 1054, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111054

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging

Author(s): Ruben D. Houvast, Mireille Vankemmelbeke, Lindy G. Durrant, Manfred Wuhrer, Victor M. Baart, Peter J. K. Kuppen, Lioe-Fee de Geus-Oei, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Published in: Cancers, Issue 12/12, 2020, Page(s) 3870, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123870

Chemical, Antioxidant, and Antimicrobial Properties of the Peel and Male Flower By-Products of Four Varieties of Punica granatum L. Cultivated in the Marche Region for Their Use in Cosmetic Products.

Author(s): Maria Rosa Gigliobianco; Manuela Cortese; Samanta Nannini; Lucrezia Di Nicolantonio; Dolores Vargas Peregrina; Giulio Lupidi; Luca Agostino Vitali; Elena Bocchietto; Piera Di Martino; Roberta Censi
Published in: Antioxidants; Volume 11; Issue 4; Pages: 768, Issue 1, 2022, ISSN 2076-3921
Publisher: S
DOI: 10.3390/antiox11040768

Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties

Author(s): Claudia Morilla, Elianis Perdomo, Ana Karla Hernández, Ramcy Regalado, Amisel Almirall, Gastón Fuentes, Yaima Campos Mora, Timo Schomann, Alan Chan, Luis J. Cruz
Published in: Molecules, Issue 26/11, 2021, Page(s) 3272, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26113272

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier.

Author(s): Jomarien García-Couce, Miriela Tomás, Gastón Fuentes, Ivo Que, Amisel Almirall and Luis J. Cruz
Published in: Gels, Issue 23102861, 2022, Page(s) 8/1, ISSN 2310-2861
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8010044

M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer.

Author(s): Ruben V Huis In 't Veld, Pablo Lara, Martine J Jager, Roman I Koning, Ferry Ossendorp, Luis J Cruz
Published in: Journal of Nanobiotechnology, Issue 14773155, 2022, ISSN 1477-3155
Publisher: BioMed Central
DOI: 10.1186/s12951-022-01448-z

CEA, EpCAM, αvβ6 and uPAR Expression in Rectal Cancer Patients with a Pathological Complete Response after Neoadjuvant Therapy

Author(s): Daan Linders,Marion Deken, Maxime van der Valk,Willemieke Tummers,Shadhvi Bhairosingh, Dennis Schaap, Gesina van Lijnschoten, Elham Zonoobi, Peter Kuppen ,Cornelis van de Velde, Alexander Vahrmeijer,Arantza Farina Sarasqueta,Cornelis Sier and Denise Hilling
Published in: Diagnostics, Issue 20754418, 2021, ISSN 2075-4418
Publisher: MDPI
DOI: 10.3390/diagnostics11030516

Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer

Author(s): Ana Luiza C. de S.L. Oliveira, Luana Zerillo, Luis J. Cruz, Timo Schomann, Alan B. Chan, Thaís Gomes de Carvalho, Shirley Vitória de P. Souza, Aurigena A. Araújo, Lioe-Fee de Geus-Oei, Raimundo F. de Araújo Júnior
Published in: Materials Science and Engineering: C, Issue 120, 2021, Page(s) 111678, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2020.111678

Identification of a novel RNA aptamer that selectively targets breast cancer exosomes

Author(s): Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Published in: Molecular Therapy - Nucleic Acids, 2021, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2021.01.012

Fluorinated PLGA-PEG-Mannose Nanoparticles for Tumor-Associated Macrophage Detection by Optical Imaging and MRI

Author(s): Giorgia Zambito, Siyuan Deng, Joost Haeck, Natasa Gaspar, Uwe Himmelreich, Roberta Censi, Clemens Löwik, Piera Di Martino, Laura Mezzanotte
Published in: Frontiers in Medicine, Issue 8, 2021, ISSN 2296-858X
Publisher: Front Med
DOI: 10.3389/fmed.2021.712367

Synthesis and Evaluation of AlgNa-g-Poly(QCL-co-HEMA) Hydrogels as Platform for Chondrocyte Proliferation and Controlled Release of Betamethasone

Author(s): Jomarien García-Couce, Marioly Vernhes, Nancy Bada, Lissette Agüero, Oscar Valdés, José Alvarez-Barreto, Gastón Fuentes, Amisel Almirall, Luis J. Cruz
Published in: International Journal of Molecular Sciences, Issue 22/11, 2021, Page(s) 5730, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22115730

Achieving effective multimodal imaging with lanthanide-doped CaF2 nanoparticles

Author(s): Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich and Luis J. Cruz
Published in: Pharmaceutics, Issue 19994923, 2022, Page(s) 840, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14040840

Extracellular Vesicles from M1-Polarized Macrophages Combined with Hyaluronic Acid and a β-Blocker Potentiate Doxorubicin's Antitumor Activity by Downregulating Tumor-Associated Macrophages in Breast Cancer

Author(s): Carla Jorquera-Cordero, Pablo Lara, Luis Cruz, Timo Schomann, Anna Van Hofslot, Thaís Gomes De Carvalho, Paulo Marcos Da Matta Guedes, Laura Creemers, Alan Chan, Romman I. Konning and Raimundo Fernandes De Araujo Junior
Published in: Pharmaceutics, Issue 19994923, 2022, Page(s) 1068, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14051068

Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues

Author(s): Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest, Marcelo J. Kogan
Published in: Pharmaceutics, Issue 12/11, 2020, Page(s) 1022, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111022

Cosmetic Formulation Based on an Açai Extract

Author(s): Roberta Censi, Dolores Vargas Peregrina, Giovanna Lacava, Dimitrios Agas, Giulio Lupidi, Maria Sabbieti, Piera Di Martino
Published in: Cosmetics, Issue 5/3, 2018, Page(s) 48, ISSN 2079-9284
Publisher: MDPI
DOI: 10.3390/cosmetics5030048

An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma.

Author(s): Ruben D. Houvast,Kira Thijse,Jesse V. Groen,JiaXin Chua, Mireille Vankemmelbeke,Lindy G. Durrant,J. Sven D. Mieog,Bert A. Bonsing, Alexander L. Vahrmeijer, Peter J. K. Kuppen, A. Stijn L. P. Crobach and Cornelis F. M. Sier
Published in: CANCERS, Issue 20726694, 2021, Page(s) 13(22):5777, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13225777

PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells

Author(s): Luis J. Cruz, Thamar van Dijk, Olena Vepris, Tracy M.W.Y. Li, Timo Schomann, Fabio Baldazzi, Ryo Kurita, Yukio Nakamura, Frank Grosveld, Sjaak Philipsen, Christina Eich
Published in: Biomaterials, Issue 268, 2021, Page(s) 120580, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120580

Photodynamic cancer therapy enhances accumulation of nanoparticles in tumor-associated myeloid cells

Author(s): Ruben V. Huis in 't Veld, Laila Ritsma, Jan Willem Kleinovink, Ivo Que, Ferry Ossendorp, Luis J. Cruz
Published in: Journal of Controlled Release, Issue 320, 2020, Page(s) 19-31, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.12.052

Autologous tumor‑derived microvesicles influence gene expression profiles and enhance protumorigenic chemotactic potential, signal transduction and cellular respiration in gastric cancer cells

Author(s): Rafal Szatanek, Kazimierz Weglarczyk, Malgorzata Stec, Jaroslaw Baran, Magdalena Parlinska‑Wojtan, Maciej Siedlar, Monika Baj‑Krzyworzeka
Published in: International Journal of Oncology, 2019, ISSN 1019-6439
Publisher: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/ijo.2019.4923

Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging

Author(s): Giorgia Zambito, Mary P. Hall, Monika G. Wood, Natasa Gaspar, Yanto Ridwan, Fabio F. Stellari, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
Published in: iScience, Issue 24/1, 2021, Page(s) 101986, ISSN 2589-0042
Publisher: Elvisier
DOI: 10.1016/j.isci.2020.101986

Thermosensitive Injectable Hydrogels for Intra-Articular Delivery of Etanercept for the Treatment of Osteoarthritis

Author(s): Jomarien García-Couce,Timo Schomann,Chih Kit Chung,Ivo Que,Carla Jorquera-Cordero,Gastón Fuentes,Amisel Almirall,Alan Chan and Luis J. Cruz.
Published in: Gels, Issue 23102861, 2022, Page(s) 8(8), 488, ISSN 2310-2861
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8080488

Upconversion nanoparticle platform for efficient dendritic cell antigen delivery and simultaneous tracking.

Author(s): Zhenfeng Yu, Olena Vepris, Christina Eich, Yansong Feng, Ivo Que, Marcel G. M. Camps, Hong Zhang, Ferry A. Ossendorp & Luis J. Cruz
Published in: Microchimica Acta, Issue 14365073, 2022, ISSN 1436-5073
Publisher: Springer
DOI: 10.1007/s00604-022-05441-z

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Author(s): Siyuan Deng, Alessandra Iscaro, Giorgia Zambito, Yimin Mijiti, Marco Minicucci, Magnus Essand, Clemens Lowik, Munitta Muthana, Roberta Censi, Laura Mezzanotte, Piera Di Martino
Published in: Nanomaterials, Issue 11/1, 2021, Page(s) 144, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11010144

Impact of the Interactions between Fragrances and Cosmetic Bases on the Fragrance Olfactory Performance: A Tentative to Correlate SPME-GC/MS Analysis with That of an Experienced Perfumer

Author(s): Lucrezia Di Nicolantonio, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Simone Angeloni, Luca Ilorini, Piera Di Martino and Roberta Censi
Published in: Cosmetics, Issue 20799284, 2022, Page(s) 70, ISSN 2079-9284
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cosmetics9040070

Smart Polymeric Micelles for Anticancer Hydrophobic Drugs

Author(s): Andy Guzmán Rodríguez, Marquiza Sablón Carrazana, Chrislayne Rodríguez Tanty, Martijn J. A. Malessy, Gastón Fuentez
Published in: Cancers, 2023, Page(s) 15/1, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15010004

Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach

Author(s): Maria Rosa Gigliobianco, Barbara Campisi, Dolores Vargas Peregrina, Roberta Censi, Gulzhan Khamitova, Simone Angeloni, Giovanni Caprioli, Marco Zannotti, Stefano Ferraro, Rita Giovannetti, Cristina Angeloni, Giulio Lupidi, Letizia Pruccoli, Andrea Tarozzi, Dario Voinovich, Piera Di Martino
Published in: Antioxidants, Issue 9/5, 2020, Page(s) 370, ISSN 2076-3921
Publisher: x
DOI: 10.3390/antiox9050370

Nanocarriers as a Tool for the Treatment of Colorectal Cancer

Author(s): Ana Luiza C. de S. L. Oliveira, Timo Schomann, Lioe-Fee de Geus-Oei, Ellen Kapiteijn, Luis J. Cruz, Raimundo Fernandes de Araújo Junior
Published in: Pharmaceutics, Issue 13/8, 2021, Page(s) 1321, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13081321

Near-infrared bioluminescence imaging of two cell populations in living mice

Author(s): Giorgia Zambito, Laura Mezzanotte
Published in: STAR Protocols, Issue 2/3, 2021, Page(s) 100662, ISSN 2666-1667
Publisher: Cell Press Open Access
DOI: 10.1016/j.xpro.2021.100662

Granulocytes and Cells of Granulocyte Origin—The Relevant Players in Colorectal Cancer

Author(s): Izabela Siemińska, Ewa Poljańska, Jarek Baran
Published in: International Journal of Molecular Sciences, Issue 22/7, 2021, Page(s) 3801, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22073801

Rare-Earth-Metal (Nd3+, Ce3+ and Gd3+)-Doped CaF2: Nanoparticles for Multimodal Imaging in Biomedical Applications

Author(s): Zhenfeng Yu, Yuanyuan He, Timo Schomann , Kefan Wu, Yang Hao, Ernst Suidgeest , Hong Zhang , Christina Eich, Luis J Cruz
Published in: Pharmaceutics, Issue 14/12, 2022, Page(s) 2796, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122796

The Incorporation of Etanercept into a Porous Tri-Layer Scaffold for Restoring and Repairing Cartilage Tissue

Author(s): Yaima Campos, Gastón Fuentes, Amisel Almirall, Ivo Que, Timo Schomann, Chih Kit Chung, Carla Jorquera-Cordero, Luis Quintanilla, José C. Rodríguez-Cabello, Alan Chan and Luis J. Cruz
Published in: Pharmaceutics, Issue 14/2, 2022, Page(s) 282, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020282

Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability

Author(s): Maria Gigliobianco, Cristina Casadidio, Roberta Censi, Piera Di Martino
Published in: Pharmaceutics, Issue 10/3, 2018, Page(s) 134, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030134

Diverse Functions of Macrophages in Different Tumor Microenvironments

Author(s): Ming Yang, Daniel McKay, Jeffrey W. Pollard, Claire E. Lewis
Published in: Cancer Research, Issue 78/19, 2018, Page(s) 5492-5503, ISSN 0008-5472
Publisher: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-18-1367

Combinatory therapy adopting nanoparticle-based cancer vaccination with immune checkpoint blockade for treatment of post-surgical tumor recurrences

Author(s): Chih Kit Chung, C.G. Da Silva, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
Published in: Journal of Controlled Release, Issue 285, 2018, Page(s) 56-66, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2018.07.011

Opportunities of bacterial cellulose to treat epithelial tissues

Author(s): Irene Anton-Sales, Uwe Beekmann, Anna Laromaine, Anna Roig, Dana Kralisch
Published in: Current Drug Targets, Issue 20, 2018, Page(s) 808-822, ISSN 1389-4501
Publisher: Bentham Science Publishers
DOI: 10.2174/1389450120666181129092144

pH-responsive poly(lactide-co-glycolide) nanoparticles containing near-infrared dye for visualization and hyaluronic acid for treatment of osteoarthritis

Author(s): L. Zerrillo, I. Que, O. Vepris, L.N. Morgado, A. Chan, K. Bierau, Y. Li, F. Galli, E. Bos, R. Censi, P. Di Martino, G.J.V.M. van Osch, L.J. Cruz
Published in: Journal of Controlled Release, Issue 309, 2019, Page(s) 265-276, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.07.031

Quantification of phenolic compounds in different types of crafts beers, worts, starting and spent ingredients by liquid chromatography-tandem mass spectrometry

Author(s): Manuela Cortese, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Gianni Sagratini, Roberta Censi, Piera Di Martino
Published in: Journal of Chromatography A, 2019, Page(s) 460622, ISSN 0021-9673
Publisher: Elsevier BV
DOI: 10.1016/j.chroma.2019.460622

Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles

Author(s): Candido G. Da Silva, Marcel G.M. Camps, Tracy M.W.Y. Li, Luana Zerrillo, Clemens W. Löwik, Ferry Ossendorp, Luis J. Cruz
Published in: Theranostics, Issue 9/22, 2019, Page(s) 6485-6500, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.34429

Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer

Author(s): Silvia Nuzzo, Giuseppina Roscigno, Alessandra Affinito, Francesco Ingenito, Cristina Quintavalle, Gerolama Condorelli
Published in: Cancers, Issue 11/10, 2019, Page(s) 1521, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101521

Applications of Noble Metal-Based Nanoparticles in Medicine

Author(s): Bartosz Klębowski, Joanna Depciuch, Magdalena Parlińska-Wojtan, Jarek Baran
Published in: International Journal of Molecular Sciences, Issue 19/12, 2018, Page(s) 4031, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19124031

ICAM3-Fc Outperforms Receptor-Specific Antibodies Targeted Nanoparticles to Dendritic Cells for Cross-Presentation

Author(s): Luis J. Cruz, Paul J. Tacken, Johan M.S. van der Schoot, Felix Rueda, Ruurd Torensma, Carl G. Figdor
Published in: Molecules, Issue 24/9, 2019, Page(s) 1825, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24091825

Thermosensitive hybrid hyaluronan/p(HPMAm‐lac)‐PEG hydrogels enhance cartilage regeneration in a mouse model of osteoarthritis

Author(s): Dimitrios Agas, Fulvio Laus, Giovanna Lacava, Andrea Marchegiani, Siyuan Deng, Federico Magnoni, Guilherme Gusmão Silva, Piera Di Martino, Maria Giovanna Sabbieti, Roberta Censi
Published in: Journal of Cellular Physiology, Issue 234/11, 2019, Page(s) 20013-20027, ISSN 0021-9541
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jcp.28598

Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process

Author(s): Roberta Censi, Maria Gigliobianco, Cristina Casadidio, Piera Di Martino
Published in: Pharmaceutics, Issue 10/3, 2018, Page(s) 89, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030089

Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers

Author(s): Yansong Feng, Haoran Chen, Yanni Wu, Ivo Que, Filippo Tamburini, Fabio Baldazzi, Yulei Chang, Hong Zhang
Published in: Biomaterials, Issue 230, 2020, Page(s) 119637, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119637

Co-delivery of immunomodulators in biodegradable nanoparticles improves therapeutic efficacy of cancer vaccines

Author(s): C.G. Da Silva, M.G.M. Camps, T.M.W.Y. Li, A.B. Chan, F. Ossendorp, L.J. Cruz
Published in: Biomaterials, Issue 220, 2019, Page(s) 119417, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119417

Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy

Author(s): Yansong Feng, Yanni Wu, Jing Zuo, Langping Tu, Ivo Que, Yulei Chang, Luis J. Cruz, Alan Chan, Hong Zhang
Published in: Biomaterials, Issue 201, 2019, Page(s) 33-41, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.02.015

Irradiation-free photodynamic therapy in vivo induced by enhanced deep red afterglow within NIR-I bio-window

Author(s): Jian Yang, Yangyang Zhao, Yangqi Meng, Hancheng Zhu, Duanting Yan, Chunguang Liu, Changshan Xu, Hong Zhang, Lin Xu, Yuxin Li, Yuxue Liu
Published in: Chemical Engineering Journal, Issue 387, 2020, Page(s) 124067, ISSN 1385-8947
Publisher: Elsevier BV
DOI: 10.1016/j.cej.2020.124067

Effect of Oxaliplatin-Loaded Poly (d,l-Lactide-co-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer

Author(s): Ana Luiza C. de S. L. Oliveira, Raimundo Fernandes de Araújo Júnior, Thaís Gomes de Carvalho, Alan B. Chan, Timo Schomann, Filippo Tamburini, Lioe-Fee de Geus-Oei, Luis J. Cruz
Published in: Pharmaceutics, Issue 12/2, 2020, Page(s) 193, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12020193

Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Author(s): Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Published in: Molecules, Issue 25/5, 2020, Page(s) 1181, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25051181

Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells

Author(s): Alessandra Affinito, Cristina Quintavalle, Carla Lucia Esposito, Giuseppina Roscigno, Catello Giordano, Silvia Nuzzo, Lucia Ricci-Vitiani, Iolanda Scognamiglio, Zoran Minic, Roberto Pallini, Maxim V. Berezovski, Vittorio de Francisis, Gerolama Condorelli
Published in: Molecular Therapy - Nucleic Acids, Issue 20, 2020, Page(s) 176-185, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2020.02.005

miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment

Author(s): Giuseppina Roscigno, Assunta Cirella, Alessandra Affinito, Cristina Quintavalle, Iolanda Scognamiglio, Francesco Palma, Francesco Ingenito, Silvia Nuzzo, Francesca De Micco, Antonio Cuccuru, Renato Thomas, Gerolama Condorelli
Published in: International Journal of Molecular Sciences, Issue 21/7, 2020, Page(s) 2313, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072313

Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies

Author(s): Chih Kit Chung, Marieke F. Fransen, Koen van der Maaden, Yaima Campos, Jomarien García-Couce, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
Published in: Journal of Controlled Release, 2020, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2020.03.050

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

Author(s): Siyuan Deng, Maria Rosa Gigliobianco, Roberta Censi, Piera Di Martino
Published in: Nanomaterials, Issue 10/5, 2020, Page(s) 847, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano10050847

Doxorubicin Loaded Poloxamer Thermosensitive Hydrogels: Chemical, Pharmacological and Biological Evaluation

Author(s): Chih Kit Chung, Jomarien García-Couce, Yaima Campos, Dana Kralisch, Katja Bierau, Alan Chan, Ferry Ossendorp, Luis Javier Cruz
Published in: Molecules, Issue 25/9, 2020, Page(s) 2219, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25092219

Author(s): Joanna Depciuch, Bartosz Klębowski, Małgorzata Stec, Rafał Szatanek, Kazimierz Węglarczyk, Monika Baj-Krzyworzeka, Magdalena Parlińska-Wojtan, Jarek Baran
Published in: International Journal of Molecular Sciences, Issue 21/5, 2020, Page(s) 1826, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21051826

Ceramide and palmitic acid inhibit macrophage-mediated epithelial–mesenchymal transition in colorectal cancer

Author(s): Raimundo Fernandes de Araujo Junior, Christina Eich, Carla Jorquera, Timo Schomann, Fabio Baldazzi, Alan B. Chan, Luis J. Cruz
Published in: Molecular and Cellular Biochemistry, Issue 468/1-2, 2020, Page(s) 153-168, ISSN 0300-8177
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11010-020-03719-5

Cholesterol-functionalized carvedilol-loaded PLGA nanoparticles: anti-inflammatory, antioxidant, and antitumor effects

Author(s): Ana Luiza C. de S. L. Oliveira, Alaine M. dos Santos-Silva, Arnóbio A. da Silva-Júnior, Vinícius B. Garcia, Aurigena A. de Araújo, Lioe-Fee de Geus-Oei, Alan B. Chan, Luis J. Cruz, Raimundo F. de Araújo Júnior
Published in: Journal of Nanoparticle Research, Issue 22/5, 2020, ISSN 1388-0764
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s11051-020-04832-8

The level of myeloid derived-suppressor cells in peripheral blood of patients with prostate cancerafter various types of therapy

Author(s): Izabela Siemińska, Edyta Rychlicka-Buniowska, Janusz Jaszczyński, Mikołaj Palaczyński, Karolina Bukowska-Strakova, Janusz Ryś, Jan Dumański, Maciej Siedlar, Jarosław Baran
Published in: Polish Journal of Pathology, Issue 71/1, 2020, Page(s) 46-54, ISSN 1233-9687
Publisher: Polskie Towarzystwo Patologow/Polish Society of Pathologists
DOI: 10.5114/pjp.2020.95415

Compensate for or Minimize Matrix Effects? Strategies for Overcoming Matrix Effects in Liquid Chromatography-Mass Spectrometry Technique: A Tutorial Review

Author(s): Manuela Cortese, Maria Rosa Gigliobianco, Federico Magnoni, Roberta Censi, Piera Di Martino
Published in: Molecules, Issue 25/13, 2020, Page(s) 3047, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25133047

Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics

Author(s): Zhenfeng Yu, Christina Eich, Luis J. Cruz
Published in: Frontiers in Chemistry, Issue 8, 2020, ISSN 2296-2646
Publisher: Frontiers in Chemestry
DOI: 10.3389/fchem.2020.00496

Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

Author(s): Ruben D. Houvast, Victor M. Baart, Shadhvi S. Bhairosingh, Robert A. Cordfunke, Jia Xin Chua, Mireille Vankemmelbeke, Tina Parsons, Peter J. K. Kuppen, Lindy G. Durrant, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Published in: Molecular Imaging and Biology, Issue Aug 11, 2020, 2020, ISSN 1536-1632
Publisher: Elsevier BV
DOI: 10.1007/s11307-020-01522-8

Fancy-Shaped Gold–Platinum Nanocauliflowers for Improved Proton Irradiation Effect on Colon Cancer Cells

Author(s): Bartosz Klebowski, Joanna Depciuch, Malgorzata Stec, Dawid Krzempek, Wiktor Komenda, Jarek Baran, Magdalena Parlinska-Wojtan
Published in: International Journal of Molecular Sciences, Issue 21/24, 2020, Page(s) 9610, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21249610

Multifunctional role of lipids in modulating the tumorigenic properties of breast cancer cells

Author(s): Yuanyuan He, Somayeh Rezaei, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz and Christina Eich
Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, Page(s) 4240, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23084240

NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice—A Novel in Vivo Imaging Platform

Author(s): Natasa Gaspar, Giorgia Zambito, Iris J. C. Dautzenberg, Steve J. Cramer, Rob C. Hoeben, Clemens Lowik, Joel R. Walker, Thomas A. Kirkland, Thomas P. Smith, Wytske M. van Weerden, Jeroen de Vrij, Laura Mezzanotte
Published in: International Journal of Molecular Sciences, Issue 21/16, 2020, Page(s) 5863, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21165863

Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging

Author(s): Giorgia Zambito, Natasa Gaspar, Yanto Ridwan, Mary P. Hall, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
Published in: Molecular Imaging and Biology, 2020, ISSN 1536-1632
Publisher: Elsevier BV
DOI: 10.1007/s11307-020-01523-7

Myeloid-Derived Suppressor Cells in Colorectal Cancer

Author(s): Izabela Sieminska, Jarek Baran
Published in: Frontiers in Immunology, Issue 11, 2020, Page(s) Article 1526, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2020.01526

Perivascular macrophages in health and disease

Author(s): Antonio Lapenna, Michele De Palma, Claire E. Lewis
Published in: Nature Reviews Immunology, Issue 18/11, 2018, Page(s) 689-702, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-018-0056-9

The Effects of Crosslinking on the Rheology and Cellular Behavior of Polymer-Based 3D-Multilayered Scaffolds for Restoring Articular Cartilage

Author(s): Yaima Campos, Francisco J. Sola, Gastón Fuentes, Luis Quintanilla, Amisel Almirall, Luis J. Cruz, José C. Rodríguez-Cabello, Yasuhiko Tabata
Published in: Polymers, Issue 13/6, 2021, Page(s) 907, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym13060907

The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature

Author(s): Silvia Nuzzo, Valentina Brancato, Alessandra Affinito, Marco Salvatore, Carlo Cavaliere, Gerolama Condorelli
Published in: Cancers, Issue 12/8, 2020, Page(s) 2173, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082173

STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

Author(s): Rômulo S. Cavalcante, Uta Ishikawa, Emanuell S. Silva, Arnóbio A. Silva‐Júnior, Aurigena A. Araújo, Luis J. Cruz, Alan B. Chan, Raimundo F. Araújo Júnior
Published in: British Journal of Pharmacology, 2021, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.15373

Emerging tools for bioluminescence imaging

Author(s): Giorgia Zambito, Chintan Chawda, Laura Mezzanotte
Published in: Current Opinion in Chemical Biology, Issue 63, 2021, Page(s) 86-94, ISSN 1367-5931
Publisher: Elsevier BV
DOI: 10.1016/j.cbpa.2021.02.005

Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies

Author(s): Chih Kit Chung; Uwe Beekmann; Dana Kralisch; Katja Bierau; Alan Chan; Ferry Ossendorp; Luis J. Cruz
Published in: Pharmaceutics; Volume 14; Issue 7; Pages: 1351, Issue 1, 2022, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14071351

Small Molecules for Multi-Wavelength Near-Infrared Fluorescent Mapping of Regional and Sentinel Lymph Nodes in Colorectal Cancer Staging

Author(s): Victor M Baart, Marion M Deken, Mark W Bordo, Shadhvi S Bhairosingh, Daniela C F Salvatori, Hoon Hyun, Maged Henary, Hak Soo Choi, Cornelis F M Sier, Peter J K Kuppen, Anton G T Terwisscha van Scheltinga, Taryn L March, Adrianus R P M Valentijn, John V Frangioni, Alexander L Vahrmeijer
Published in: Frontiers in Oncology, Issue 2234943X, 2020, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.586112

Interpenetrating Hydrogel Networks Enhance Mechanical Stability, Rheological Properties, Release Behavior and Adhesiveness of Platelet-Rich Plasma

Author(s): Roberta Censi, Cristina Casadidio, Siyuan Deng, Maria Rosa Gigliobianco, Maria Giovanna Sabbieti, Dimitrios Agas, Fulvio Laus, Piera Di Martino
Published in: International Journal of Molecular Sciences, Issue 21/4, 2020, Page(s) 1399, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21041399

Po-260 deep phenotyping of colorectal cancers by high-dimensional mass cytometry reveals tumor-specific immune landscapes

Author(s): N De Vries, V Van Unen, T Abdelaal, M Van Herk, R Van der Breggen, A Farina Sarasqueta, T Höllt, B Lelieveldt, F Koning, N De Miranda
Published in: Tumour Microenvironment, 2018, Page(s) A328.2-A329
Publisher: BMJ Publishing Group Ltd
DOI: 10.1136/esmoopen-2018-EACR25.775

Construction and Optimization of Biofunctional Upconversion Nanoplatforms

Author(s): Yadan Ding
Published in: 2018
Publisher: Ipskamp Printing

Triplet-Triplet Annihilation PLGA-Nanoparticles for Cancer Bioimaging

Author(s): Olena Vepris, Christina Eich, Yansong Feng, Hong Zhang, Eric. L. Kaijzel, Luis J. Cruz
Published in: Biorxiv, 2020
Publisher: Biorxiv
DOI: 10.1101/2020.09.02.274969

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