Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Established network organisation and management structure
Annual gender equality monitoring

Publikacje

The Anti-Tumor Effect of Lactococcus lactis Bacteria-Secreting Human Soluble TRAIL Can Be Enhanced by Metformin Both In Vitro and In Vivo in a Mouse Model of Human Colorectal Cancer

Autorzy: Katarzyna Kaczmarek, Jerzy Więckiewicz, Kazimierz Węglarczyk, Maciej Siedlar, Jarek Baran
Opublikowane w: Cancers, Numer 13/12, 2021, Strona(/y) 3004, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13123004

Chitin and Chitosans: Characteristics, Eco-Friendly Processes, and Applications in Cosmetic Science

Autorzy: Cristina Casadidio, Dolores Vargas Peregrina, Maria Rosa Gigliobianco, Siyuan Deng, Roberta Censi, Piera Di Martino
Opublikowane w: Marine Drugs, Numer 17/6, 2019, Strona(/y) 369, ISSN 1660-3397
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md17060369

Zinc-Phthalocyanine-Loaded Extracellular Vesicles Increase Efficacy and Selectivity of Photodynamic Therapy in Co-Culture and Preclinical Models of Colon Cancer.

Autorzy: Pablo Lara, Ruben V. Huis in ‘t Veld,Carla Jorquera-Cordero, Alan B. Chan,Ferry Ossendorp andLuis J. Cruz
Opublikowane w: Farmaceutics, Numer 20794991, 2021, ISSN 2079-4991
Wydawca: MPDI
DOI: 10.3390/pharmaceutics13101547

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Autorzy: Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle
Opublikowane w: Cancer Gene Therapy, 2020, ISSN 0929-1903
Wydawca: Nature Publishing Group
DOI: 10.1038/s41417-020-00224-1

Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment

Autorzy: Yang Hao, Chih Kit Chung, Zili Gu, Timo Schomann, Xiaoxu Dong, Ruben V Huis In 't Veld, Marcel G M Camps, Peter Ten Dijke, Ferry A Ossendorp, Luis J Cruz
Opublikowane w: Molecular biomedicine, 2022, ISSN 2662-8651
Wydawca: Singapore : Springer Singapore, [2020]
DOI: 10.1186/s43556-022-00086-z

Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice

Autorzy: Natasa Gaspar, Joel R. Walker, Giorgia Zambito, Kranthi Marella-Panth, Clemens Lowik, Thomas A. Kirkland, Laura Mezzanotte
Opublikowane w: Journal of Photochemistry and Photobiology B: Biology, Numer 216, 2021, Strona(/y) 112128, ISSN 1011-1344
Wydawca: Elsevier BV
DOI: 10.1016/j.jphotobiol.2021.112128

Liposome-Based Drug Delivery Systems in Cancer Immunotherapy

Autorzy: Zili Gu, Candido G. Da Silva, Koen Van der Maaden, Ferry Ossendorp, Luis J. Cruz
Opublikowane w: Pharmaceutics, Numer 12/11, 2020, Strona(/y) 1054, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111054

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging

Autorzy: Ruben D. Houvast, Mireille Vankemmelbeke, Lindy G. Durrant, Manfred Wuhrer, Victor M. Baart, Peter J. K. Kuppen, Lioe-Fee de Geus-Oei, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Opublikowane w: Cancers, Numer 12/12, 2020, Strona(/y) 3870, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123870

Chemical, Antioxidant, and Antimicrobial Properties of the Peel and Male Flower By-Products of Four Varieties of Punica granatum L. Cultivated in the Marche Region for Their Use in Cosmetic Products.

Autorzy: Maria Rosa Gigliobianco; Manuela Cortese; Samanta Nannini; Lucrezia Di Nicolantonio; Dolores Vargas Peregrina; Giulio Lupidi; Luca Agostino Vitali; Elena Bocchietto; Piera Di Martino; Roberta Censi
Opublikowane w: Antioxidants; Volume 11; Numer 4; Pages: 768, Numer 1, 2022, ISSN 2076-3921
Wydawca: S
DOI: 10.3390/antiox11040768

Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties

Autorzy: Claudia Morilla, Elianis Perdomo, Ana Karla Hernández, Ramcy Regalado, Amisel Almirall, Gastón Fuentes, Yaima Campos Mora, Timo Schomann, Alan Chan, Luis J. Cruz
Opublikowane w: Molecules, Numer 26/11, 2021, Strona(/y) 3272, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26113272

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier.

Autorzy: Jomarien García-Couce, Miriela Tomás, Gastón Fuentes, Ivo Que, Amisel Almirall and Luis J. Cruz
Opublikowane w: Gels, Numer 23102861, 2022, Strona(/y) 8/1, ISSN 2310-2861
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8010044

M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer.

Autorzy: Ruben V Huis In 't Veld, Pablo Lara, Martine J Jager, Roman I Koning, Ferry Ossendorp, Luis J Cruz
Opublikowane w: Journal of Nanobiotechnology, Numer 14773155, 2022, ISSN 1477-3155
Wydawca: BioMed Central
DOI: 10.1186/s12951-022-01448-z

CEA, EpCAM, αvβ6 and uPAR Expression in Rectal Cancer Patients with a Pathological Complete Response after Neoadjuvant Therapy

Autorzy: Daan Linders,Marion Deken, Maxime van der Valk,Willemieke Tummers,Shadhvi Bhairosingh, Dennis Schaap, Gesina van Lijnschoten, Elham Zonoobi, Peter Kuppen ,Cornelis van de Velde, Alexander Vahrmeijer,Arantza Farina Sarasqueta,Cornelis Sier and Denise Hilling
Opublikowane w: Diagnostics, Numer 20754418, 2021, ISSN 2075-4418
Wydawca: MDPI
DOI: 10.3390/diagnostics11030516

Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer

Autorzy: Ana Luiza C. de S.L. Oliveira, Luana Zerillo, Luis J. Cruz, Timo Schomann, Alan B. Chan, Thaís Gomes de Carvalho, Shirley Vitória de P. Souza, Aurigena A. Araújo, Lioe-Fee de Geus-Oei, Raimundo F. de Araújo Júnior
Opublikowane w: Materials Science and Engineering: C, Numer 120, 2021, Strona(/y) 111678, ISSN 0928-4931
Wydawca: Elsevier BV
DOI: 10.1016/j.msec.2020.111678

Identification of a novel RNA aptamer that selectively targets breast cancer exosomes

Autorzy: Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Opublikowane w: Molecular Therapy - Nucleic Acids, 2021, ISSN 2162-2531
Wydawca: Nature Publishing Group
DOI: 10.1016/j.omtn.2021.01.012

Fluorinated PLGA-PEG-Mannose Nanoparticles for Tumor-Associated Macrophage Detection by Optical Imaging and MRI

Autorzy: Giorgia Zambito, Siyuan Deng, Joost Haeck, Natasa Gaspar, Uwe Himmelreich, Roberta Censi, Clemens Löwik, Piera Di Martino, Laura Mezzanotte
Opublikowane w: Frontiers in Medicine, Numer 8, 2021, ISSN 2296-858X
Wydawca: Front Med
DOI: 10.3389/fmed.2021.712367

Synthesis and Evaluation of AlgNa-g-Poly(QCL-co-HEMA) Hydrogels as Platform for Chondrocyte Proliferation and Controlled Release of Betamethasone

Autorzy: Jomarien García-Couce, Marioly Vernhes, Nancy Bada, Lissette Agüero, Oscar Valdés, José Alvarez-Barreto, Gastón Fuentes, Amisel Almirall, Luis J. Cruz
Opublikowane w: International Journal of Molecular Sciences, Numer 22/11, 2021, Strona(/y) 5730, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22115730

Achieving effective multimodal imaging with lanthanide-doped CaF2 nanoparticles

Autorzy: Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich and Luis J. Cruz
Opublikowane w: Pharmaceutics, Numer 19994923, 2022, Strona(/y) 840, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14040840

Extracellular Vesicles from M1-Polarized Macrophages Combined with Hyaluronic Acid and a β-Blocker Potentiate Doxorubicin's Antitumor Activity by Downregulating Tumor-Associated Macrophages in Breast Cancer

Autorzy: Carla Jorquera-Cordero, Pablo Lara, Luis Cruz, Timo Schomann, Anna Van Hofslot, Thaís Gomes De Carvalho, Paulo Marcos Da Matta Guedes, Laura Creemers, Alan Chan, Romman I. Konning and Raimundo Fernandes De Araujo Junior
Opublikowane w: Pharmaceutics, Numer 19994923, 2022, Strona(/y) 1068, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14051068

Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues

Autorzy: Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest, Marcelo J. Kogan
Opublikowane w: Pharmaceutics, Numer 12/11, 2020, Strona(/y) 1022, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111022

Cosmetic Formulation Based on an Açai Extract

Autorzy: Roberta Censi, Dolores Vargas Peregrina, Giovanna Lacava, Dimitrios Agas, Giulio Lupidi, Maria Sabbieti, Piera Di Martino
Opublikowane w: Cosmetics, Numer 5/3, 2018, Strona(/y) 48, ISSN 2079-9284
Wydawca: MDPI
DOI: 10.3390/cosmetics5030048

An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma.

Autorzy: Ruben D. Houvast,Kira Thijse,Jesse V. Groen,JiaXin Chua, Mireille Vankemmelbeke,Lindy G. Durrant,J. Sven D. Mieog,Bert A. Bonsing, Alexander L. Vahrmeijer, Peter J. K. Kuppen, A. Stijn L. P. Crobach and Cornelis F. M. Sier
Opublikowane w: CANCERS, Numer 20726694, 2021, Strona(/y) 13(22):5777, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13225777

PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells

Autorzy: Luis J. Cruz, Thamar van Dijk, Olena Vepris, Tracy M.W.Y. Li, Timo Schomann, Fabio Baldazzi, Ryo Kurita, Yukio Nakamura, Frank Grosveld, Sjaak Philipsen, Christina Eich
Opublikowane w: Biomaterials, Numer 268, 2021, Strona(/y) 120580, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120580

Photodynamic cancer therapy enhances accumulation of nanoparticles in tumor-associated myeloid cells

Autorzy: Ruben V. Huis in 't Veld, Laila Ritsma, Jan Willem Kleinovink, Ivo Que, Ferry Ossendorp, Luis J. Cruz
Opublikowane w: Journal of Controlled Release, Numer 320, 2020, Strona(/y) 19-31, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2019.12.052

Autologous tumor‑derived microvesicles influence gene expression profiles and enhance protumorigenic chemotactic potential, signal transduction and cellular respiration in gastric cancer cells

Autorzy: Rafal Szatanek, Kazimierz Weglarczyk, Malgorzata Stec, Jaroslaw Baran, Magdalena Parlinska‑Wojtan, Maciej Siedlar, Monika Baj‑Krzyworzeka
Opublikowane w: International Journal of Oncology, 2019, ISSN 1019-6439
Wydawca: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/ijo.2019.4923

Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging

Autorzy: Giorgia Zambito, Mary P. Hall, Monika G. Wood, Natasa Gaspar, Yanto Ridwan, Fabio F. Stellari, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
Opublikowane w: iScience, Numer 24/1, 2021, Strona(/y) 101986, ISSN 2589-0042
Wydawca: Elvisier
DOI: 10.1016/j.isci.2020.101986

Thermosensitive Injectable Hydrogels for Intra-Articular Delivery of Etanercept for the Treatment of Osteoarthritis

Autorzy: Jomarien García-Couce,Timo Schomann,Chih Kit Chung,Ivo Que,Carla Jorquera-Cordero,Gastón Fuentes,Amisel Almirall,Alan Chan and Luis J. Cruz.
Opublikowane w: Gels, Numer 23102861, 2022, Strona(/y) 8(8), 488, ISSN 2310-2861
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8080488

Upconversion nanoparticle platform for efficient dendritic cell antigen delivery and simultaneous tracking.

Autorzy: Zhenfeng Yu, Olena Vepris, Christina Eich, Yansong Feng, Ivo Que, Marcel G. M. Camps, Hong Zhang, Ferry A. Ossendorp & Luis J. Cruz
Opublikowane w: Microchimica Acta, Numer 14365073, 2022, ISSN 1436-5073
Wydawca: Springer
DOI: 10.1007/s00604-022-05441-z

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Autorzy: Siyuan Deng, Alessandra Iscaro, Giorgia Zambito, Yimin Mijiti, Marco Minicucci, Magnus Essand, Clemens Lowik, Munitta Muthana, Roberta Censi, Laura Mezzanotte, Piera Di Martino
Opublikowane w: Nanomaterials, Numer 11/1, 2021, Strona(/y) 144, ISSN 2079-4991
Wydawca: MDPI
DOI: 10.3390/nano11010144

Impact of the Interactions between Fragrances and Cosmetic Bases on the Fragrance Olfactory Performance: A Tentative to Correlate SPME-GC/MS Analysis with That of an Experienced Perfumer

Autorzy: Lucrezia Di Nicolantonio, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Simone Angeloni, Luca Ilorini, Piera Di Martino and Roberta Censi
Opublikowane w: Cosmetics, Numer 20799284, 2022, Strona(/y) 70, ISSN 2079-9284
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cosmetics9040070

Smart Polymeric Micelles for Anticancer Hydrophobic Drugs

Autorzy: Andy Guzmán Rodríguez, Marquiza Sablón Carrazana, Chrislayne Rodríguez Tanty, Martijn J. A. Malessy, Gastón Fuentez
Opublikowane w: Cancers, 2023, Strona(/y) 15/1, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15010004

Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach

Autorzy: Maria Rosa Gigliobianco, Barbara Campisi, Dolores Vargas Peregrina, Roberta Censi, Gulzhan Khamitova, Simone Angeloni, Giovanni Caprioli, Marco Zannotti, Stefano Ferraro, Rita Giovannetti, Cristina Angeloni, Giulio Lupidi, Letizia Pruccoli, Andrea Tarozzi, Dario Voinovich, Piera Di Martino
Opublikowane w: Antioxidants, Numer 9/5, 2020, Strona(/y) 370, ISSN 2076-3921
Wydawca: x
DOI: 10.3390/antiox9050370

Nanocarriers as a Tool for the Treatment of Colorectal Cancer

Autorzy: Ana Luiza C. de S. L. Oliveira, Timo Schomann, Lioe-Fee de Geus-Oei, Ellen Kapiteijn, Luis J. Cruz, Raimundo Fernandes de Araújo Junior
Opublikowane w: Pharmaceutics, Numer 13/8, 2021, Strona(/y) 1321, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13081321

Near-infrared bioluminescence imaging of two cell populations in living mice

Autorzy: Giorgia Zambito, Laura Mezzanotte
Opublikowane w: STAR Protocols, Numer 2/3, 2021, Strona(/y) 100662, ISSN 2666-1667
Wydawca: Cell Press Open Access
DOI: 10.1016/j.xpro.2021.100662

Granulocytes and Cells of Granulocyte Origin—The Relevant Players in Colorectal Cancer

Autorzy: Izabela Siemińska, Ewa Poljańska, Jarek Baran
Opublikowane w: International Journal of Molecular Sciences, Numer 22/7, 2021, Strona(/y) 3801, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22073801

Rare-Earth-Metal (Nd3+, Ce3+ and Gd3+)-Doped CaF2: Nanoparticles for Multimodal Imaging in Biomedical Applications

Autorzy: Zhenfeng Yu, Yuanyuan He, Timo Schomann , Kefan Wu, Yang Hao, Ernst Suidgeest , Hong Zhang , Christina Eich, Luis J Cruz
Opublikowane w: Pharmaceutics, Numer 14/12, 2022, Strona(/y) 2796, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122796

The Incorporation of Etanercept into a Porous Tri-Layer Scaffold for Restoring and Repairing Cartilage Tissue

Autorzy: Yaima Campos, Gastón Fuentes, Amisel Almirall, Ivo Que, Timo Schomann, Chih Kit Chung, Carla Jorquera-Cordero, Luis Quintanilla, José C. Rodríguez-Cabello, Alan Chan and Luis J. Cruz
Opublikowane w: Pharmaceutics, Numer 14/2, 2022, Strona(/y) 282, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020282

Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability

Autorzy: Maria Gigliobianco, Cristina Casadidio, Roberta Censi, Piera Di Martino
Opublikowane w: Pharmaceutics, Numer 10/3, 2018, Strona(/y) 134, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030134

Diverse Functions of Macrophages in Different Tumor Microenvironments

Autorzy: Ming Yang, Daniel McKay, Jeffrey W. Pollard, Claire E. Lewis
Opublikowane w: Cancer Research, Numer 78/19, 2018, Strona(/y) 5492-5503, ISSN 0008-5472
Wydawca: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-18-1367

Combinatory therapy adopting nanoparticle-based cancer vaccination with immune checkpoint blockade for treatment of post-surgical tumor recurrences

Autorzy: Chih Kit Chung, C.G. Da Silva, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
Opublikowane w: Journal of Controlled Release, Numer 285, 2018, Strona(/y) 56-66, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2018.07.011

Opportunities of bacterial cellulose to treat epithelial tissues

Autorzy: Irene Anton-Sales, Uwe Beekmann, Anna Laromaine, Anna Roig, Dana Kralisch
Opublikowane w: Current Drug Targets, Numer 20, 2018, Strona(/y) 808-822, ISSN 1389-4501
Wydawca: Bentham Science Publishers
DOI: 10.2174/1389450120666181129092144

pH-responsive poly(lactide-co-glycolide) nanoparticles containing near-infrared dye for visualization and hyaluronic acid for treatment of osteoarthritis

Autorzy: L. Zerrillo, I. Que, O. Vepris, L.N. Morgado, A. Chan, K. Bierau, Y. Li, F. Galli, E. Bos, R. Censi, P. Di Martino, G.J.V.M. van Osch, L.J. Cruz
Opublikowane w: Journal of Controlled Release, Numer 309, 2019, Strona(/y) 265-276, ISSN 0168-3659
Wydawca: Elsevier BV
DOI: 10.1016/j.jconrel.2019.07.031

Quantification of phenolic compounds in different types of crafts beers, worts, starting and spent ingredients by liquid chromatography-tandem mass spectrometry

Autorzy: Manuela Cortese, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Gianni Sagratini, Roberta Censi, Piera Di Martino
Opublikowane w: Journal of Chromatography A, 2019, Strona(/y) 460622, ISSN 0021-9673
Wydawca: Elsevier BV
DOI: 10.1016/j.chroma.2019.460622

Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles

Autorzy: Candido G. Da Silva, Marcel G.M. Camps, Tracy M.W.Y. Li, Luana Zerrillo, Clemens W. Löwik, Ferry Ossendorp, Luis J. Cruz
Opublikowane w: Theranostics, Numer 9/22, 2019, Strona(/y) 6485-6500, ISSN 1838-7640
Wydawca: Ivyspring International Publisher
DOI: 10.7150/thno.34429

Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer

Autorzy: Silvia Nuzzo, Giuseppina Roscigno, Alessandra Affinito, Francesco Ingenito, Cristina Quintavalle, Gerolama Condorelli
Opublikowane w: Cancers, Numer 11/10, 2019, Strona(/y) 1521, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101521

Applications of Noble Metal-Based Nanoparticles in Medicine

Autorzy: Bartosz Klębowski, Joanna Depciuch, Magdalena Parlińska-Wojtan, Jarek Baran
Opublikowane w: International Journal of Molecular Sciences, Numer 19/12, 2018, Strona(/y) 4031, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19124031

ICAM3-Fc Outperforms Receptor-Specific Antibodies Targeted Nanoparticles to Dendritic Cells for Cross-Presentation

Autorzy: Luis J. Cruz, Paul J. Tacken, Johan M.S. van der Schoot, Felix Rueda, Ruurd Torensma, Carl G. Figdor
Opublikowane w: Molecules, Numer 24/9, 2019, Strona(/y) 1825, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24091825

Thermosensitive hybrid hyaluronan/p(HPMAm‐lac)‐PEG hydrogels enhance cartilage regeneration in a mouse model of osteoarthritis

Autorzy: Dimitrios Agas, Fulvio Laus, Giovanna Lacava, Andrea Marchegiani, Siyuan Deng, Federico Magnoni, Guilherme Gusmão Silva, Piera Di Martino, Maria Giovanna Sabbieti, Roberta Censi
Opublikowane w: Journal of Cellular Physiology, Numer 234/11, 2019, Strona(/y) 20013-20027, ISSN 0021-9541
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jcp.28598

Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process

Autorzy: Roberta Censi, Maria Gigliobianco, Cristina Casadidio, Piera Di Martino
Opublikowane w: Pharmaceutics, Numer 10/3, 2018, Strona(/y) 89, ISSN 1999-4923
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030089

Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers

Autorzy: Yansong Feng, Haoran Chen, Yanni Wu, Ivo Que, Filippo Tamburini, Fabio Baldazzi, Yulei Chang, Hong Zhang
Opublikowane w: Biomaterials, Numer 230, 2020, Strona(/y) 119637, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119637

Co-delivery of immunomodulators in biodegradable nanoparticles improves therapeutic efficacy of cancer vaccines

Autorzy: C.G. Da Silva, M.G.M. Camps, T.M.W.Y. Li, A.B. Chan, F. Ossendorp, L.J. Cruz
Opublikowane w: Biomaterials, Numer 220, 2019, Strona(/y) 119417, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119417

Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy

Autorzy: Yansong Feng, Yanni Wu, Jing Zuo, Langping Tu, Ivo Que, Yulei Chang, Luis J. Cruz, Alan Chan, Hong Zhang
Opublikowane w: Biomaterials, Numer 201, 2019, Strona(/y) 33-41, ISSN 0142-9612
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.02.015

Irradiation-free photodynamic therapy in vivo induced by enhanced deep red afterglow within NIR-I bio-window

Autorzy: Jian Yang, Yangyang Zhao, Yangqi Meng, Hancheng Zhu, Duanting Yan, Chunguang Liu, Changshan Xu, Hong Zhang, Lin Xu, Yuxin Li, Yuxue Liu
Opublikowane w: Chemical Engineering Journal, Numer 387, 2020, Strona(/y) 124067, ISSN 1385-8947
Wydawca: Elsevier BV
DOI: 10.1016/j.cej.2020.124067

Effect of Oxaliplatin-Loaded Poly (d,l-Lactide-co-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer

Autorzy: Ana Luiza C. de S. L. Oliveira, Raimundo Fernandes de Araújo Júnior, Thaís Gomes de Carvalho, Alan B. Chan, Timo Schomann, Filippo Tamburini, Lioe-Fee de Geus-Oei, Luis J. Cruz
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Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Autorzy: Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Opublikowane w: Molecules, Numer 25/5, 2020, Strona(/y) 1181, ISSN 1420-3049
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Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells

Autorzy: Alessandra Affinito, Cristina Quintavalle, Carla Lucia Esposito, Giuseppina Roscigno, Catello Giordano, Silvia Nuzzo, Lucia Ricci-Vitiani, Iolanda Scognamiglio, Zoran Minic, Roberto Pallini, Maxim V. Berezovski, Vittorio de Francisis, Gerolama Condorelli
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miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment

Autorzy: Giuseppina Roscigno, Assunta Cirella, Alessandra Affinito, Cristina Quintavalle, Iolanda Scognamiglio, Francesco Palma, Francesco Ingenito, Silvia Nuzzo, Francesca De Micco, Antonio Cuccuru, Renato Thomas, Gerolama Condorelli
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Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies

Autorzy: Chih Kit Chung, Marieke F. Fransen, Koen van der Maaden, Yaima Campos, Jomarien García-Couce, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
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Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

Autorzy: Siyuan Deng, Maria Rosa Gigliobianco, Roberta Censi, Piera Di Martino
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Doxorubicin Loaded Poloxamer Thermosensitive Hydrogels: Chemical, Pharmacological and Biological Evaluation

Autorzy: Chih Kit Chung, Jomarien García-Couce, Yaima Campos, Dana Kralisch, Katja Bierau, Alan Chan, Ferry Ossendorp, Luis Javier Cruz
Opublikowane w: Molecules, Numer 25/9, 2020, Strona(/y) 2219, ISSN 1420-3049
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Autorzy: Joanna Depciuch, Bartosz Klębowski, Małgorzata Stec, Rafał Szatanek, Kazimierz Węglarczyk, Monika Baj-Krzyworzeka, Magdalena Parlińska-Wojtan, Jarek Baran
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Ceramide and palmitic acid inhibit macrophage-mediated epithelial–mesenchymal transition in colorectal cancer

Autorzy: Raimundo Fernandes de Araujo Junior, Christina Eich, Carla Jorquera, Timo Schomann, Fabio Baldazzi, Alan B. Chan, Luis J. Cruz
Opublikowane w: Molecular and Cellular Biochemistry, Numer 468/1-2, 2020, Strona(/y) 153-168, ISSN 0300-8177
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Cholesterol-functionalized carvedilol-loaded PLGA nanoparticles: anti-inflammatory, antioxidant, and antitumor effects

Autorzy: Ana Luiza C. de S. L. Oliveira, Alaine M. dos Santos-Silva, Arnóbio A. da Silva-Júnior, Vinícius B. Garcia, Aurigena A. de Araújo, Lioe-Fee de Geus-Oei, Alan B. Chan, Luis J. Cruz, Raimundo F. de Araújo Júnior
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The level of myeloid derived-suppressor cells in peripheral blood of patients with prostate cancerafter various types of therapy

Autorzy: Izabela Siemińska, Edyta Rychlicka-Buniowska, Janusz Jaszczyński, Mikołaj Palaczyński, Karolina Bukowska-Strakova, Janusz Ryś, Jan Dumański, Maciej Siedlar, Jarosław Baran
Opublikowane w: Polish Journal of Pathology, Numer 71/1, 2020, Strona(/y) 46-54, ISSN 1233-9687
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Compensate for or Minimize Matrix Effects? Strategies for Overcoming Matrix Effects in Liquid Chromatography-Mass Spectrometry Technique: A Tutorial Review

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Opublikowane w: Molecules, Numer 25/13, 2020, Strona(/y) 3047, ISSN 1420-3049
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Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics

Autorzy: Zhenfeng Yu, Christina Eich, Luis J. Cruz
Opublikowane w: Frontiers in Chemistry, Numer 8, 2020, ISSN 2296-2646
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Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

Autorzy: Ruben D. Houvast, Victor M. Baart, Shadhvi S. Bhairosingh, Robert A. Cordfunke, Jia Xin Chua, Mireille Vankemmelbeke, Tina Parsons, Peter J. K. Kuppen, Lindy G. Durrant, Alexander L. Vahrmeijer, Cornelis F. M. Sier
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Fancy-Shaped Gold–Platinum Nanocauliflowers for Improved Proton Irradiation Effect on Colon Cancer Cells

Autorzy: Bartosz Klebowski, Joanna Depciuch, Malgorzata Stec, Dawid Krzempek, Wiktor Komenda, Jarek Baran, Magdalena Parlinska-Wojtan
Opublikowane w: International Journal of Molecular Sciences, Numer 21/24, 2020, Strona(/y) 9610, ISSN 1422-0067
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Multifunctional role of lipids in modulating the tumorigenic properties of breast cancer cells

Autorzy: Yuanyuan He, Somayeh Rezaei, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz and Christina Eich
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NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice—A Novel in Vivo Imaging Platform

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Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging

Autorzy: Giorgia Zambito, Natasa Gaspar, Yanto Ridwan, Mary P. Hall, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
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Myeloid-Derived Suppressor Cells in Colorectal Cancer

Autorzy: Izabela Sieminska, Jarek Baran
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Perivascular macrophages in health and disease

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The Effects of Crosslinking on the Rheology and Cellular Behavior of Polymer-Based 3D-Multilayered Scaffolds for Restoring Articular Cartilage

Autorzy: Yaima Campos, Francisco J. Sola, Gastón Fuentes, Luis Quintanilla, Amisel Almirall, Luis J. Cruz, José C. Rodríguez-Cabello, Yasuhiko Tabata
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The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature

Autorzy: Silvia Nuzzo, Valentina Brancato, Alessandra Affinito, Marco Salvatore, Carlo Cavaliere, Gerolama Condorelli
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STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

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Emerging tools for bioluminescence imaging

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Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies

Autorzy: Chih Kit Chung; Uwe Beekmann; Dana Kralisch; Katja Bierau; Alan Chan; Ferry Ossendorp; Luis J. Cruz
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Small Molecules for Multi-Wavelength Near-Infrared Fluorescent Mapping of Regional and Sentinel Lymph Nodes in Colorectal Cancer Staging

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Interpenetrating Hydrogel Networks Enhance Mechanical Stability, Rheological Properties, Release Behavior and Adhesiveness of Platelet-Rich Plasma

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Po-260 deep phenotyping of colorectal cancers by high-dimensional mass cytometry reveals tumor-specific immune landscapes

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Construction and Optimization of Biofunctional Upconversion Nanoplatforms

Autorzy: Yadan Ding
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Triplet-Triplet Annihilation PLGA-Nanoparticles for Cancer Bioimaging

Autorzy: Olena Vepris, Christina Eich, Yansong Feng, Hong Zhang, Eric. L. Kaijzel, Luis J. Cruz
Opublikowane w: Biorxiv, 2020
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