Personalised Postoperative Immunotherapy To Improving Cancer Outcome and improving quality of life

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Established network organisation and management structure
Annual gender equality monitoring

Publications

The Anti-Tumor Effect of Lactococcus lactis Bacteria-Secreting Human Soluble TRAIL Can Be Enhanced by Metformin Both In Vitro and In Vivo in a Mouse Model of Human Colorectal Cancer

Auteurs: Katarzyna Kaczmarek, Jerzy Więckiewicz, Kazimierz Węglarczyk, Maciej Siedlar, Jarek Baran
Publié dans: Cancers, Numéro 13/12, 2021, Page(s) 3004, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13123004

Chitin and Chitosans: Characteristics, Eco-Friendly Processes, and Applications in Cosmetic Science

Auteurs: Cristina Casadidio, Dolores Vargas Peregrina, Maria Rosa Gigliobianco, Siyuan Deng, Roberta Censi, Piera Di Martino
Publié dans: Marine Drugs, Numéro 17/6, 2019, Page(s) 369, ISSN 1660-3397
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/md17060369

Zinc-Phthalocyanine-Loaded Extracellular Vesicles Increase Efficacy and Selectivity of Photodynamic Therapy in Co-Culture and Preclinical Models of Colon Cancer.

Auteurs: Pablo Lara, Ruben V. Huis in ‘t Veld,Carla Jorquera-Cordero, Alan B. Chan,Ferry Ossendorp andLuis J. Cruz
Publié dans: Farmaceutics, Numéro 20794991, 2021, ISSN 2079-4991
Éditeur: MPDI
DOI: 10.3390/pharmaceutics13101547

miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer

Auteurs: Francesco Palma, Alessandra Affinito, Silvia Nuzzo, Giuseppina Roscigno, Iolanda Scognamiglio, Francesco Ingenito, Lola Martinez, Monica Franzese, Mario Zanfardino, Andrea Soricelli, Alfonso Fiorelli, Gerolama Condorelli, Cristina Quintavalle
Publié dans: Cancer Gene Therapy, 2020, ISSN 0929-1903
Éditeur: Nature Publishing Group
DOI: 10.1038/s41417-020-00224-1

Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment

Auteurs: Yang Hao, Chih Kit Chung, Zili Gu, Timo Schomann, Xiaoxu Dong, Ruben V Huis In 't Veld, Marcel G M Camps, Peter Ten Dijke, Ferry A Ossendorp, Luis J Cruz
Publié dans: Molecular biomedicine, 2022, ISSN 2662-8651
Éditeur: Singapore : Springer Singapore, [2020]
DOI: 10.1186/s43556-022-00086-z

Evaluation of NanoLuc substrates for bioluminescence imaging of transferred cells in mice

Auteurs: Natasa Gaspar, Joel R. Walker, Giorgia Zambito, Kranthi Marella-Panth, Clemens Lowik, Thomas A. Kirkland, Laura Mezzanotte
Publié dans: Journal of Photochemistry and Photobiology B: Biology, Numéro 216, 2021, Page(s) 112128, ISSN 1011-1344
Éditeur: Elsevier BV
DOI: 10.1016/j.jphotobiol.2021.112128

Liposome-Based Drug Delivery Systems in Cancer Immunotherapy

Auteurs: Zili Gu, Candido G. Da Silva, Koen Van der Maaden, Ferry Ossendorp, Luis J. Cruz
Publié dans: Pharmaceutics, Numéro 12/11, 2020, Page(s) 1054, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111054

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging

Auteurs: Ruben D. Houvast, Mireille Vankemmelbeke, Lindy G. Durrant, Manfred Wuhrer, Victor M. Baart, Peter J. K. Kuppen, Lioe-Fee de Geus-Oei, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Publié dans: Cancers, Numéro 12/12, 2020, Page(s) 3870, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12123870

Chemical, Antioxidant, and Antimicrobial Properties of the Peel and Male Flower By-Products of Four Varieties of Punica granatum L. Cultivated in the Marche Region for Their Use in Cosmetic Products.

Auteurs: Maria Rosa Gigliobianco; Manuela Cortese; Samanta Nannini; Lucrezia Di Nicolantonio; Dolores Vargas Peregrina; Giulio Lupidi; Luca Agostino Vitali; Elena Bocchietto; Piera Di Martino; Roberta Censi
Publié dans: Antioxidants; Volume 11; Numéro 4; Pages: 768, Numéro 1, 2022, ISSN 2076-3921
Éditeur: S
DOI: 10.3390/antiox11040768

Effect of the Addition of Alginate and/or Tetracycline on Brushite Cement Properties

Auteurs: Claudia Morilla, Elianis Perdomo, Ana Karla Hernández, Ramcy Regalado, Amisel Almirall, Gastón Fuentes, Yaima Campos Mora, Timo Schomann, Alan Chan, Luis J. Cruz
Publié dans: Molecules, Numéro 26/11, 2021, Page(s) 3272, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules26113272

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier.

Auteurs: Jomarien García-Couce, Miriela Tomás, Gastón Fuentes, Ivo Que, Amisel Almirall and Luis J. Cruz
Publié dans: Gels, Numéro 23102861, 2022, Page(s) 8/1, ISSN 2310-2861
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8010044

M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer.

Auteurs: Ruben V Huis In 't Veld, Pablo Lara, Martine J Jager, Roman I Koning, Ferry Ossendorp, Luis J Cruz
Publié dans: Journal of Nanobiotechnology, Numéro 14773155, 2022, ISSN 1477-3155
Éditeur: BioMed Central
DOI: 10.1186/s12951-022-01448-z

CEA, EpCAM, αvβ6 and uPAR Expression in Rectal Cancer Patients with a Pathological Complete Response after Neoadjuvant Therapy

Auteurs: Daan Linders,Marion Deken, Maxime van der Valk,Willemieke Tummers,Shadhvi Bhairosingh, Dennis Schaap, Gesina van Lijnschoten, Elham Zonoobi, Peter Kuppen ,Cornelis van de Velde, Alexander Vahrmeijer,Arantza Farina Sarasqueta,Cornelis Sier and Denise Hilling
Publié dans: Diagnostics, Numéro 20754418, 2021, ISSN 2075-4418
Éditeur: MDPI
DOI: 10.3390/diagnostics11030516

Maximizing the potency of oxaliplatin coated nanoparticles with folic acid for modulating tumor progression in colorectal cancer

Auteurs: Ana Luiza C. de S.L. Oliveira, Luana Zerillo, Luis J. Cruz, Timo Schomann, Alan B. Chan, Thaís Gomes de Carvalho, Shirley Vitória de P. Souza, Aurigena A. Araújo, Lioe-Fee de Geus-Oei, Raimundo F. de Araújo Júnior
Publié dans: Materials Science and Engineering: C, Numéro 120, 2021, Page(s) 111678, ISSN 0928-4931
Éditeur: Elsevier BV
DOI: 10.1016/j.msec.2020.111678

Identification of a novel RNA aptamer that selectively targets breast cancer exosomes

Auteurs: Carla Lucia Esposito, Cristina Quintavalle, Francesco Ingenito, Deborah Rotoli, Giuseppina Roscigno, Silvia Nuzzo, Renato Thomas, Silvia Catuogno, Vittorio de Franciscis, Gerolama Condorelli
Publié dans: Molecular Therapy - Nucleic Acids, 2021, ISSN 2162-2531
Éditeur: Nature Publishing Group
DOI: 10.1016/j.omtn.2021.01.012

Fluorinated PLGA-PEG-Mannose Nanoparticles for Tumor-Associated Macrophage Detection by Optical Imaging and MRI

Auteurs: Giorgia Zambito, Siyuan Deng, Joost Haeck, Natasa Gaspar, Uwe Himmelreich, Roberta Censi, Clemens Löwik, Piera Di Martino, Laura Mezzanotte
Publié dans: Frontiers in Medicine, Numéro 8, 2021, ISSN 2296-858X
Éditeur: Front Med
DOI: 10.3389/fmed.2021.712367

Synthesis and Evaluation of AlgNa-g-Poly(QCL-co-HEMA) Hydrogels as Platform for Chondrocyte Proliferation and Controlled Release of Betamethasone

Auteurs: Jomarien García-Couce, Marioly Vernhes, Nancy Bada, Lissette Agüero, Oscar Valdés, José Alvarez-Barreto, Gastón Fuentes, Amisel Almirall, Luis J. Cruz
Publié dans: International Journal of Molecular Sciences, Numéro 22/11, 2021, Page(s) 5730, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22115730

Achieving effective multimodal imaging with lanthanide-doped CaF2 nanoparticles

Auteurs: Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich and Luis J. Cruz
Publié dans: Pharmaceutics, Numéro 19994923, 2022, Page(s) 840, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14040840

Extracellular Vesicles from M1-Polarized Macrophages Combined with Hyaluronic Acid and a β-Blocker Potentiate Doxorubicin's Antitumor Activity by Downregulating Tumor-Associated Macrophages in Breast Cancer

Auteurs: Carla Jorquera-Cordero, Pablo Lara, Luis Cruz, Timo Schomann, Anna Van Hofslot, Thaís Gomes De Carvalho, Paulo Marcos Da Matta Guedes, Laura Creemers, Alan Chan, Romman I. Konning and Raimundo Fernandes De Araujo Junior
Publié dans: Pharmaceutics, Numéro 19994923, 2022, Page(s) 1068, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14051068

Exploiting the Natural Properties of Extracellular Vesicles in Targeted Delivery towards Specific Cells and Tissues

Auteurs: Pablo Lara, Alan B. Chan, Luis J. Cruz, Andrew F. G. Quest, Marcelo J. Kogan
Publié dans: Pharmaceutics, Numéro 12/11, 2020, Page(s) 1022, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12111022

Cosmetic Formulation Based on an Açai Extract

Auteurs: Roberta Censi, Dolores Vargas Peregrina, Giovanna Lacava, Dimitrios Agas, Giulio Lupidi, Maria Sabbieti, Piera Di Martino
Publié dans: Cosmetics, Numéro 5/3, 2018, Page(s) 48, ISSN 2079-9284
Éditeur: MDPI
DOI: 10.3390/cosmetics5030048

An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma.

Auteurs: Ruben D. Houvast,Kira Thijse,Jesse V. Groen,JiaXin Chua, Mireille Vankemmelbeke,Lindy G. Durrant,J. Sven D. Mieog,Bert A. Bonsing, Alexander L. Vahrmeijer, Peter J. K. Kuppen, A. Stijn L. P. Crobach and Cornelis F. M. Sier
Publié dans: CANCERS, Numéro 20726694, 2021, Page(s) 13(22):5777, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13225777

PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells

Auteurs: Luis J. Cruz, Thamar van Dijk, Olena Vepris, Tracy M.W.Y. Li, Timo Schomann, Fabio Baldazzi, Ryo Kurita, Yukio Nakamura, Frank Grosveld, Sjaak Philipsen, Christina Eich
Publié dans: Biomaterials, Numéro 268, 2021, Page(s) 120580, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2020.120580

Photodynamic cancer therapy enhances accumulation of nanoparticles in tumor-associated myeloid cells

Auteurs: Ruben V. Huis in 't Veld, Laila Ritsma, Jan Willem Kleinovink, Ivo Que, Ferry Ossendorp, Luis J. Cruz
Publié dans: Journal of Controlled Release, Numéro 320, 2020, Page(s) 19-31, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2019.12.052

Autologous tumor‑derived microvesicles influence gene expression profiles and enhance protumorigenic chemotactic potential, signal transduction and cellular respiration in gastric cancer cells

Auteurs: Rafal Szatanek, Kazimierz Weglarczyk, Malgorzata Stec, Jaroslaw Baran, Magdalena Parlinska‑Wojtan, Maciej Siedlar, Monika Baj‑Krzyworzeka
Publié dans: International Journal of Oncology, 2019, ISSN 1019-6439
Éditeur: Demetrios A. Spandidos Ed. & Pub.
DOI: 10.3892/ijo.2019.4923

Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging

Auteurs: Giorgia Zambito, Mary P. Hall, Monika G. Wood, Natasa Gaspar, Yanto Ridwan, Fabio F. Stellari, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
Publié dans: iScience, Numéro 24/1, 2021, Page(s) 101986, ISSN 2589-0042
Éditeur: Elvisier
DOI: 10.1016/j.isci.2020.101986

Thermosensitive Injectable Hydrogels for Intra-Articular Delivery of Etanercept for the Treatment of Osteoarthritis

Auteurs: Jomarien García-Couce,Timo Schomann,Chih Kit Chung,Ivo Que,Carla Jorquera-Cordero,Gastón Fuentes,Amisel Almirall,Alan Chan and Luis J. Cruz.
Publié dans: Gels, Numéro 23102861, 2022, Page(s) 8(8), 488, ISSN 2310-2861
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/gels8080488

Upconversion nanoparticle platform for efficient dendritic cell antigen delivery and simultaneous tracking.

Auteurs: Zhenfeng Yu, Olena Vepris, Christina Eich, Yansong Feng, Ivo Que, Marcel G. M. Camps, Hong Zhang, Ferry A. Ossendorp & Luis J. Cruz
Publié dans: Microchimica Acta, Numéro 14365073, 2022, ISSN 1436-5073
Éditeur: Springer
DOI: 10.1007/s00604-022-05441-z

Development of a New Hyaluronic Acid Based Redox-Responsive Nanohydrogel for the Encapsulation of Oncolytic Viruses for Cancer Immunotherapy

Auteurs: Siyuan Deng, Alessandra Iscaro, Giorgia Zambito, Yimin Mijiti, Marco Minicucci, Magnus Essand, Clemens Lowik, Munitta Muthana, Roberta Censi, Laura Mezzanotte, Piera Di Martino
Publié dans: Nanomaterials, Numéro 11/1, 2021, Page(s) 144, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano11010144

Impact of the Interactions between Fragrances and Cosmetic Bases on the Fragrance Olfactory Performance: A Tentative to Correlate SPME-GC/MS Analysis with That of an Experienced Perfumer

Auteurs: Lucrezia Di Nicolantonio, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Simone Angeloni, Luca Ilorini, Piera Di Martino and Roberta Censi
Publié dans: Cosmetics, Numéro 20799284, 2022, Page(s) 70, ISSN 2079-9284
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cosmetics9040070

Smart Polymeric Micelles for Anticancer Hydrophobic Drugs

Auteurs: Andy Guzmán Rodríguez, Marquiza Sablón Carrazana, Chrislayne Rodríguez Tanty, Martijn J. A. Malessy, Gastón Fuentez
Publié dans: Cancers, 2023, Page(s) 15/1, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15010004

Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach

Auteurs: Maria Rosa Gigliobianco, Barbara Campisi, Dolores Vargas Peregrina, Roberta Censi, Gulzhan Khamitova, Simone Angeloni, Giovanni Caprioli, Marco Zannotti, Stefano Ferraro, Rita Giovannetti, Cristina Angeloni, Giulio Lupidi, Letizia Pruccoli, Andrea Tarozzi, Dario Voinovich, Piera Di Martino
Publié dans: Antioxidants, Numéro 9/5, 2020, Page(s) 370, ISSN 2076-3921
Éditeur: x
DOI: 10.3390/antiox9050370

Nanocarriers as a Tool for the Treatment of Colorectal Cancer

Auteurs: Ana Luiza C. de S. L. Oliveira, Timo Schomann, Lioe-Fee de Geus-Oei, Ellen Kapiteijn, Luis J. Cruz, Raimundo Fernandes de Araújo Junior
Publié dans: Pharmaceutics, Numéro 13/8, 2021, Page(s) 1321, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13081321

Near-infrared bioluminescence imaging of two cell populations in living mice

Auteurs: Giorgia Zambito, Laura Mezzanotte
Publié dans: STAR Protocols, Numéro 2/3, 2021, Page(s) 100662, ISSN 2666-1667
Éditeur: Cell Press Open Access
DOI: 10.1016/j.xpro.2021.100662

Granulocytes and Cells of Granulocyte Origin—The Relevant Players in Colorectal Cancer

Auteurs: Izabela Siemińska, Ewa Poljańska, Jarek Baran
Publié dans: International Journal of Molecular Sciences, Numéro 22/7, 2021, Page(s) 3801, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22073801

Rare-Earth-Metal (Nd3+, Ce3+ and Gd3+)-Doped CaF2: Nanoparticles for Multimodal Imaging in Biomedical Applications

Auteurs: Zhenfeng Yu, Yuanyuan He, Timo Schomann , Kefan Wu, Yang Hao, Ernst Suidgeest , Hong Zhang , Christina Eich, Luis J Cruz
Publié dans: Pharmaceutics, Numéro 14/12, 2022, Page(s) 2796, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14122796

The Incorporation of Etanercept into a Porous Tri-Layer Scaffold for Restoring and Repairing Cartilage Tissue

Auteurs: Yaima Campos, Gastón Fuentes, Amisel Almirall, Ivo Que, Timo Schomann, Chih Kit Chung, Carla Jorquera-Cordero, Luis Quintanilla, José C. Rodríguez-Cabello, Alan Chan and Luis J. Cruz
Publié dans: Pharmaceutics, Numéro 14/2, 2022, Page(s) 282, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics14020282

Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability

Auteurs: Maria Gigliobianco, Cristina Casadidio, Roberta Censi, Piera Di Martino
Publié dans: Pharmaceutics, Numéro 10/3, 2018, Page(s) 134, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030134

Diverse Functions of Macrophages in Different Tumor Microenvironments

Auteurs: Ming Yang, Daniel McKay, Jeffrey W. Pollard, Claire E. Lewis
Publié dans: Cancer Research, Numéro 78/19, 2018, Page(s) 5492-5503, ISSN 0008-5472
Éditeur: American Association for Cancer Research
DOI: 10.1158/0008-5472.CAN-18-1367

Combinatory therapy adopting nanoparticle-based cancer vaccination with immune checkpoint blockade for treatment of post-surgical tumor recurrences

Auteurs: Chih Kit Chung, C.G. Da Silva, Dana Kralisch, Alan Chan, Ferry Ossendorp, Luis J. Cruz
Publié dans: Journal of Controlled Release, Numéro 285, 2018, Page(s) 56-66, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2018.07.011

Opportunities of bacterial cellulose to treat epithelial tissues

Auteurs: Irene Anton-Sales, Uwe Beekmann, Anna Laromaine, Anna Roig, Dana Kralisch
Publié dans: Current Drug Targets, Numéro 20, 2018, Page(s) 808-822, ISSN 1389-4501
Éditeur: Bentham Science Publishers
DOI: 10.2174/1389450120666181129092144

pH-responsive poly(lactide-co-glycolide) nanoparticles containing near-infrared dye for visualization and hyaluronic acid for treatment of osteoarthritis

Auteurs: L. Zerrillo, I. Que, O. Vepris, L.N. Morgado, A. Chan, K. Bierau, Y. Li, F. Galli, E. Bos, R. Censi, P. Di Martino, G.J.V.M. van Osch, L.J. Cruz
Publié dans: Journal of Controlled Release, Numéro 309, 2019, Page(s) 265-276, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2019.07.031

Quantification of phenolic compounds in different types of crafts beers, worts, starting and spent ingredients by liquid chromatography-tandem mass spectrometry

Auteurs: Manuela Cortese, Maria Rosa Gigliobianco, Dolores Vargas Peregrina, Gianni Sagratini, Roberta Censi, Piera Di Martino
Publié dans: Journal of Chromatography A, 2019, Page(s) 460622, ISSN 0021-9673
Éditeur: Elsevier BV
DOI: 10.1016/j.chroma.2019.460622

Effective chemoimmunotherapy by co-delivery of doxorubicin and immune adjuvants in biodegradable nanoparticles

Auteurs: Candido G. Da Silva, Marcel G.M. Camps, Tracy M.W.Y. Li, Luana Zerrillo, Clemens W. Löwik, Ferry Ossendorp, Luis J. Cruz
Publié dans: Theranostics, Numéro 9/22, 2019, Page(s) 6485-6500, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.34429

Potential and Challenges of Aptamers as Specific Carriers of Therapeutic Oligonucleotides for Precision Medicine in Cancer

Auteurs: Silvia Nuzzo, Giuseppina Roscigno, Alessandra Affinito, Francesco Ingenito, Cristina Quintavalle, Gerolama Condorelli
Publié dans: Cancers, Numéro 11/10, 2019, Page(s) 1521, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers11101521

Applications of Noble Metal-Based Nanoparticles in Medicine

Auteurs: Bartosz Klębowski, Joanna Depciuch, Magdalena Parlińska-Wojtan, Jarek Baran
Publié dans: International Journal of Molecular Sciences, Numéro 19/12, 2018, Page(s) 4031, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms19124031

ICAM3-Fc Outperforms Receptor-Specific Antibodies Targeted Nanoparticles to Dendritic Cells for Cross-Presentation

Auteurs: Luis J. Cruz, Paul J. Tacken, Johan M.S. van der Schoot, Felix Rueda, Ruurd Torensma, Carl G. Figdor
Publié dans: Molecules, Numéro 24/9, 2019, Page(s) 1825, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24091825

Thermosensitive hybrid hyaluronan/p(HPMAm‐lac)‐PEG hydrogels enhance cartilage regeneration in a mouse model of osteoarthritis

Auteurs: Dimitrios Agas, Fulvio Laus, Giovanna Lacava, Andrea Marchegiani, Siyuan Deng, Federico Magnoni, Guilherme Gusmão Silva, Piera Di Martino, Maria Giovanna Sabbieti, Roberta Censi
Publié dans: Journal of Cellular Physiology, Numéro 234/11, 2019, Page(s) 20013-20027, ISSN 0021-9541
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jcp.28598

Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process

Auteurs: Roberta Censi, Maria Gigliobianco, Cristina Casadidio, Piera Di Martino
Publié dans: Pharmaceutics, Numéro 10/3, 2018, Page(s) 89, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics10030089

Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers

Auteurs: Yansong Feng, Haoran Chen, Yanni Wu, Ivo Que, Filippo Tamburini, Fabio Baldazzi, Yulei Chang, Hong Zhang
Publié dans: Biomaterials, Numéro 230, 2020, Page(s) 119637, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119637

Co-delivery of immunomodulators in biodegradable nanoparticles improves therapeutic efficacy of cancer vaccines

Auteurs: C.G. Da Silva, M.G.M. Camps, T.M.W.Y. Li, A.B. Chan, F. Ossendorp, L.J. Cruz
Publié dans: Biomaterials, Numéro 220, 2019, Page(s) 119417, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.119417

Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy

Auteurs: Yansong Feng, Yanni Wu, Jing Zuo, Langping Tu, Ivo Que, Yulei Chang, Luis J. Cruz, Alan Chan, Hong Zhang
Publié dans: Biomaterials, Numéro 201, 2019, Page(s) 33-41, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2019.02.015

Irradiation-free photodynamic therapy in vivo induced by enhanced deep red afterglow within NIR-I bio-window

Auteurs: Jian Yang, Yangyang Zhao, Yangqi Meng, Hancheng Zhu, Duanting Yan, Chunguang Liu, Changshan Xu, Hong Zhang, Lin Xu, Yuxin Li, Yuxue Liu
Publié dans: Chemical Engineering Journal, Numéro 387, 2020, Page(s) 124067, ISSN 1385-8947
Éditeur: Elsevier BV
DOI: 10.1016/j.cej.2020.124067

Effect of Oxaliplatin-Loaded Poly (d,l-Lactide-co-Glycolic Acid) (PLGA) Nanoparticles Combined with Retinoic Acid and Cholesterol on Apoptosis, Drug Resistance, and Metastasis Factors of Colorectal Cancer

Auteurs: Ana Luiza C. de S. L. Oliveira, Raimundo Fernandes de Araújo Júnior, Thaís Gomes de Carvalho, Alan B. Chan, Timo Schomann, Filippo Tamburini, Lioe-Fee de Geus-Oei, Luis J. Cruz
Publié dans: Pharmaceutics, Numéro 12/2, 2020, Page(s) 193, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12020193

Redox-Sensitive and Hyaluronic Acid-Functionalized Nanoparticles for Improving Breast Cancer Treatment by Cytoplasmic 17α-Methyltestosterone Delivery

Auteurs: Somayeh Rezaei, Soheila Kashanian, Yadollah Bahrami, Luis J. Cruz, Marjan Motiei
Publié dans: Molecules, Numéro 25/5, 2020, Page(s) 1181, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25051181

Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells

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Publié dans: Molecular Therapy - Nucleic Acids, Numéro 20, 2020, Page(s) 176-185, ISSN 2162-2531
Éditeur: Nature Publishing Group
DOI: 10.1016/j.omtn.2020.02.005

miR-216a Acts as a Negative Regulator of Breast Cancer by Modulating Stemness Properties and Tumor Microenvironment

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Publié dans: International Journal of Molecular Sciences, Numéro 21/7, 2020, Page(s) 2313, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21072313

Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies

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Publié dans: Journal of Controlled Release, 2020, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2020.03.050

Polymeric Nanocapsules as Nanotechnological Alternative for Drug Delivery System: Current Status, Challenges and Opportunities

Auteurs: Siyuan Deng, Maria Rosa Gigliobianco, Roberta Censi, Piera Di Martino
Publié dans: Nanomaterials, Numéro 10/5, 2020, Page(s) 847, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano10050847

Doxorubicin Loaded Poloxamer Thermosensitive Hydrogels: Chemical, Pharmacological and Biological Evaluation

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Publié dans: Molecules, Numéro 25/9, 2020, Page(s) 2219, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25092219

Auteurs: Joanna Depciuch, Bartosz Klębowski, Małgorzata Stec, Rafał Szatanek, Kazimierz Węglarczyk, Monika Baj-Krzyworzeka, Magdalena Parlińska-Wojtan, Jarek Baran
Publié dans: International Journal of Molecular Sciences, Numéro 21/5, 2020, Page(s) 1826, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21051826

Ceramide and palmitic acid inhibit macrophage-mediated epithelial–mesenchymal transition in colorectal cancer

Auteurs: Raimundo Fernandes de Araujo Junior, Christina Eich, Carla Jorquera, Timo Schomann, Fabio Baldazzi, Alan B. Chan, Luis J. Cruz
Publié dans: Molecular and Cellular Biochemistry, Numéro 468/1-2, 2020, Page(s) 153-168, ISSN 0300-8177
Éditeur: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11010-020-03719-5

Cholesterol-functionalized carvedilol-loaded PLGA nanoparticles: anti-inflammatory, antioxidant, and antitumor effects

Auteurs: Ana Luiza C. de S. L. Oliveira, Alaine M. dos Santos-Silva, Arnóbio A. da Silva-Júnior, Vinícius B. Garcia, Aurigena A. de Araújo, Lioe-Fee de Geus-Oei, Alan B. Chan, Luis J. Cruz, Raimundo F. de Araújo Júnior
Publié dans: Journal of Nanoparticle Research, Numéro 22/5, 2020, ISSN 1388-0764
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s11051-020-04832-8

The level of myeloid derived-suppressor cells in peripheral blood of patients with prostate cancerafter various types of therapy

Auteurs: Izabela Siemińska, Edyta Rychlicka-Buniowska, Janusz Jaszczyński, Mikołaj Palaczyński, Karolina Bukowska-Strakova, Janusz Ryś, Jan Dumański, Maciej Siedlar, Jarosław Baran
Publié dans: Polish Journal of Pathology, Numéro 71/1, 2020, Page(s) 46-54, ISSN 1233-9687
Éditeur: Polskie Towarzystwo Patologow/Polish Society of Pathologists
DOI: 10.5114/pjp.2020.95415

Compensate for or Minimize Matrix Effects? Strategies for Overcoming Matrix Effects in Liquid Chromatography-Mass Spectrometry Technique: A Tutorial Review

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Publié dans: Molecules, Numéro 25/13, 2020, Page(s) 3047, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25133047

Recent Advances in Rare-Earth-Doped Nanoparticles for NIR-II Imaging and Cancer Theranostics

Auteurs: Zhenfeng Yu, Christina Eich, Luis J. Cruz
Publié dans: Frontiers in Chemistry, Numéro 8, 2020, ISSN 2296-2646
Éditeur: Frontiers in Chemestry
DOI: 10.3389/fchem.2020.00496

Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study

Auteurs: Ruben D. Houvast, Victor M. Baart, Shadhvi S. Bhairosingh, Robert A. Cordfunke, Jia Xin Chua, Mireille Vankemmelbeke, Tina Parsons, Peter J. K. Kuppen, Lindy G. Durrant, Alexander L. Vahrmeijer, Cornelis F. M. Sier
Publié dans: Molecular Imaging and Biology, Numéro Aug 11, 2020, 2020, ISSN 1536-1632
Éditeur: Elsevier BV
DOI: 10.1007/s11307-020-01522-8

Fancy-Shaped Gold–Platinum Nanocauliflowers for Improved Proton Irradiation Effect on Colon Cancer Cells

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Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Multifunctional role of lipids in modulating the tumorigenic properties of breast cancer cells

Auteurs: Yuanyuan He, Somayeh Rezaei, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz and Christina Eich
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2022, Page(s) 4240, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice—A Novel in Vivo Imaging Platform

Auteurs: Natasa Gaspar, Giorgia Zambito, Iris J. C. Dautzenberg, Steve J. Cramer, Rob C. Hoeben, Clemens Lowik, Joel R. Walker, Thomas A. Kirkland, Thomas P. Smith, Wytske M. van Weerden, Jeroen de Vrij, Laura Mezzanotte
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Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging

Auteurs: Giorgia Zambito, Natasa Gaspar, Yanto Ridwan, Mary P. Hall, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens Löwik, Laura Mezzanotte
Publié dans: Molecular Imaging and Biology, 2020, ISSN 1536-1632
Éditeur: Elsevier BV
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Myeloid-Derived Suppressor Cells in Colorectal Cancer

Auteurs: Izabela Sieminska, Jarek Baran
Publié dans: Frontiers in Immunology, Numéro 11, 2020, Page(s) Article 1526, ISSN 1664-3224
Éditeur: Frontiers in Immunology
DOI: 10.3389/fimmu.2020.01526

Perivascular macrophages in health and disease

Auteurs: Antonio Lapenna, Michele De Palma, Claire E. Lewis
Publié dans: Nature Reviews Immunology, Numéro 18/11, 2018, Page(s) 689-702, ISSN 1474-1733
Éditeur: Nature Publishing Group
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The Effects of Crosslinking on the Rheology and Cellular Behavior of Polymer-Based 3D-Multilayered Scaffolds for Restoring Articular Cartilage

Auteurs: Yaima Campos, Francisco J. Sola, Gastón Fuentes, Luis Quintanilla, Amisel Almirall, Luis J. Cruz, José C. Rodríguez-Cabello, Yasuhiko Tabata
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Éditeur: MDPI
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The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature

Auteurs: Silvia Nuzzo, Valentina Brancato, Alessandra Affinito, Marco Salvatore, Carlo Cavaliere, Gerolama Condorelli
Publié dans: Cancers, Numéro 12/8, 2020, Page(s) 2173, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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STAT3/NF‐κB signalling disruption in M2 tumour‐associated macrophages is a major target of PLGA nanocarriers/PD‐L1 antibody immunomodulatory therapy in breast cancer

Auteurs: Rômulo S. Cavalcante, Uta Ishikawa, Emanuell S. Silva, Arnóbio A. Silva‐Júnior, Aurigena A. Araújo, Luis J. Cruz, Alan B. Chan, Raimundo F. Araújo Júnior
Publié dans: British Journal of Pharmacology, 2021, ISSN 0007-1188
Éditeur: Wiley-Blackwell
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Emerging tools for bioluminescence imaging

Auteurs: Giorgia Zambito, Chintan Chawda, Laura Mezzanotte
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Bacterial Cellulose as Drug Delivery System for Optimizing Release of Immune Checkpoint Blocking Antibodies

Auteurs: Chih Kit Chung; Uwe Beekmann; Dana Kralisch; Katja Bierau; Alan Chan; Ferry Ossendorp; Luis J. Cruz
Publié dans: Pharmaceutics; Volume 14; Numéro 7; Pages: 1351, Numéro 1, 2022, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Small Molecules for Multi-Wavelength Near-Infrared Fluorescent Mapping of Regional and Sentinel Lymph Nodes in Colorectal Cancer Staging

Auteurs: Victor M Baart, Marion M Deken, Mark W Bordo, Shadhvi S Bhairosingh, Daniela C F Salvatori, Hoon Hyun, Maged Henary, Hak Soo Choi, Cornelis F M Sier, Peter J K Kuppen, Anton G T Terwisscha van Scheltinga, Taryn L March, Adrianus R P M Valentijn, John V Frangioni, Alexander L Vahrmeijer
Publié dans: Frontiers in Oncology, Numéro 2234943X, 2020, ISSN 2234-943X
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Interpenetrating Hydrogel Networks Enhance Mechanical Stability, Rheological Properties, Release Behavior and Adhesiveness of Platelet-Rich Plasma

Auteurs: Roberta Censi, Cristina Casadidio, Siyuan Deng, Maria Rosa Gigliobianco, Maria Giovanna Sabbieti, Dimitrios Agas, Fulvio Laus, Piera Di Martino
Publié dans: International Journal of Molecular Sciences, Numéro 21/4, 2020, Page(s) 1399, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Po-260 deep phenotyping of colorectal cancers by high-dimensional mass cytometry reveals tumor-specific immune landscapes

Auteurs: N De Vries, V Van Unen, T Abdelaal, M Van Herk, R Van der Breggen, A Farina Sarasqueta, T Höllt, B Lelieveldt, F Koning, N De Miranda
Publié dans: Tumour Microenvironment, 2018, Page(s) A328.2-A329
Éditeur: BMJ Publishing Group Ltd
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Construction and Optimization of Biofunctional Upconversion Nanoplatforms

Auteurs: Yadan Ding
Publié dans: 2018
Éditeur: Ipskamp Printing

Triplet-Triplet Annihilation PLGA-Nanoparticles for Cancer Bioimaging

Auteurs: Olena Vepris, Christina Eich, Yansong Feng, Hong Zhang, Eric. L. Kaijzel, Luis J. Cruz
Publié dans: Biorxiv, 2020
Éditeur: Biorxiv
DOI: 10.1101/2020.09.02.274969

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