Heart On chip based on induced pluripotent Stem cell Technology for personalized Medicine

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Communication and public engagement plan No. 1
Report on workshops/Networking activities

Report on Workshop List of attendees work programme workshop results summary audiovisual material and slides Networking activities Events future potential collaborative project

Communication and public engagement plan No. 2

Microfluidic chip modelling the Duchenne Muscular

A microfluidic chip will be designed for modelling the Duchenne Muscular Dystrophy (DMD) cardiomyopathy

Microfluidic device for iPSC differentiation into Cardiomyocyte

Fabrication of microfluidic device dedicated to the iPSC differentiation into cardiomyocyte. The microfluidic chip will exploit a biochemical procedure for iPSC differentiation. This first prototype will be fabricated in PDMS.

Project website

project website

Publications

Surface modifications of COP-based microfluidic devices for improved immobilisation of hydrogel proteins: long-term 3D culture with contractile cell types and ischaemia model

Auteurs: Sandra González-Lana; Teodora Randelovic; Jesús Ciriza; María López-Valdeolivas; Rosa Monge; Carlos Sánchez-Somolinos; Ignacio Ochoa
Publié dans: Lab on a chip, Numéro 8, 2023, ISSN 1473-0197
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3lc00075c

Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling

Auteurs: María Virumbrales-Muñoz, Jose M. Ayuso, Alodia Lacueva, Teodora Randelovic, Megan K. Livingston, David J. Beebe, Sara Oliván, Desirée Pereboom, Manuel Doblare, Luis Fernández, Ignacio Ochoa
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-42529-8

Towards novel biomimetic in vitro models of the blood-brain barrier for drug permeability evaluation

Auteurs: Mármol, Inés; Abizanda-Campo, Sara; Ayuso, José M.; Ochoa, Ignacio; Oliván, Sara
Publié dans: Bioengineering, Numéro 10, 2023, ISSN 2306-5354
Éditeur: mdpi
DOI: 10.3390/bioengineering10050572

Current approaches for the recreation of cardiac ischaemic environment in vitro

Auteurs: Laura Paz-Artigas, Pilar Montero-Calle, Olalla Iglesias-García, Manuel M. Mazo, Ignacio Ochoa , Jesús Ciriza
Publié dans: International Journal of Pharmaceutics, 2023, ISSN 0378-5173
Éditeur: Elsevier BV
DOI: 10.1016/j.ijpharm.2023.122589

Gene therapy. The legacy of Wacław Szybalski.

Auteurs: Jozef Dulak
Publié dans: Acta Biochimica Polonica, Numéro 5, 2020, ISSN 1734-154X
Éditeur: Polskie Towarzystwo Biochemiczne
DOI: 10.18388/abp.2020_5805

Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells

Auteurs: Alicja Martyniak, Mateusz Jeż, Józef Dulak, Jacek Stępniewski
Publié dans: IUBMB Life, 2023, ISSN 1521-6551
Éditeur: John Wiley & Sons
DOI: 10.1002/iub.2685

Human-induced pluripotent stem cell-derived cardiomyocytes, 3D cardiac structures, and heart-on-a-chip as tools for drug research

Auteurs: Kalina Andrysiak; Jacek Stępniewski; Jozef Dulak
Publié dans: Pflugers Archiv - European Journal of Physiology, Numéro 3, 2021, ISSN 0031-6768
Éditeur: Springer Verlag
DOI: 10.1007/s00424-021-02536-z

Heart-on-a-chip

Auteurs: Pierre Gaudriault, Dario Fassini, Antoni Homs-Corbera
Publié dans: Organ-on-a-chip, 2020, Page(s) 255-293, ISBN 9780128172025
Éditeur: Elsevier
DOI: 10.1016/b978-0-12-817202-5.00008-5

Application of human induced pluripotent stem cells and CRISPR/Cas9 gene editing technology for investigation of molecular background of Duchenne muscular dystrophy-related cardiomyopathy

Auteurs: Kalina Andrysiak
Publié dans: 2022
Éditeur: Repozytorium Uniwersytetu Jagiellońskiego

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