Analysis of the nucleolus in genome organization and function

Project Information

NucleolusChromatin

Grant agreement ID: 787074

DOI

10.3030/787074

Project closed

EC signature date 20 April 2018

Start date 1 September 2018

End date 31 August 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

UNIVERSITAT ZURICH
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

BAZ2A‐mediated repression via H3K14ac‐marked enhancers promotes prostate cancer stem cells

Author(s): Rodrigo Peña‐Hernández, Rossana Aprigliano, Sandra Carina Frommel, Karolina Pietrzak, Seraina Steiger, Marcin Roganowicz, Luigi Lerra, Juliana Bizzarro, Raffaella Santoro
Published in: EMBO reports, 2021, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.202153014

Methods for mapping 3D-chromosome architecture around nucleoli

Author(s): Cristiana Bersaglieri, Raffaella Santoro
Published in: Current Opinion in Cell Biology, Issue 81, 2023, Page(s) 102171, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2023.102171

BAZ 2A safeguards genome architecture of ground‐state pluripotent stem cells

Author(s): Damian Dalcher, Jennifer Yihong Tan, Cristiana Bersaglieri, Rodrigo Peña‐Hernández, Eva Vollenweider, Stefan Zeyen, Marc W Schmid, Valerio Bianchi, Stefan Butz, Marcin Roganowicz, Rostyslav Kuzyakiv, Tuncay Baubec, Ana Claudia Marques, Raffaella Santoro
Published in: The EMBO Journal, Issue 39/23, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020105606

Argonaute proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells

Author(s): Madlen Müller, Moritz Schaefer, Tara Fäh, Daniel Spies, Victoria Hermes, Richard Patryk Ngondo, Rodrigo Peña-Hernández, Raffaella Santoro, Constance Ciaudo
Published in: Stem Cell Reports, 2022, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2022.03.014

Image analysis workflows to reveal the spatial organization of cell nuclei and chromosomes

Author(s): Ricardo S Randall, Claire Jourdain, Anna Nowicka, Kateřina Kaduchová, Michaela Kubová, Mohammad A Ayoub, Veit Schubert, Christophe Tatout, Isabelle Colas, Kalyanikrishna, Sophie Desset, Sarah Mermet, Aurélia Boulaflous-Stevens, Ivona Kubalová, Terezie Mandáková, Stefan Heckmann, Martin A Lysak, Martina Panatta, Raffaella Santoro, Daniel Schubert, Ales Pecinka, Devin Routh, Célia Baroux
Published in: Nucleus, 2022, ISSN 1949-1034
Publisher: Landes Bioscience
DOI: 10.1080/19491034.2022.2144013

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains

Author(s): Cristiana Bersaglieri, Jelena Kresoja-Rakic, Shivani Gupta, Dominik Bär, Rostyslav Kuzyakiv, Martina Panatta, Raffaella Santoro
Published in: Nature communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-29146-2

Regulation and Roles of the Nucleolus in Embryonic Stem Cells: From Ribosome Biogenesis to Genome Organization

Author(s): Shivani Gupta, Raffaella Santoro
Published in: Stem Cell Reports, Issue 15/6, 2020, Page(s) 1206-1219, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2020.08.012

Nucleolus and rRNA Gene Chromatin in Early Embryo Development

Author(s): Jelena Kresoja-Rakic, Raffaella Santoro
Published in: Trends in Genetics, Issue 35/11, 2019, Page(s) 868-879, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2019.06.005

Genome Organization in and around the Nucleolus

Author(s): Cristiana Bersaglieri, Raffaella Santoro
Published in: Cells, Issue 8/6, 2019, Page(s) 579, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells8060579

BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer

Author(s): Marcin Roganowicz, Dominik Bär, Cristiana Bersaglieri, Rossana Aprigliano, Raffaella Santoro
Published in: Life Science Alliance, Issue 6, 2024, Page(s) e202301950, ISSN 2575-1077
Publisher: Life Science Alliance
DOI: 10.26508/lsa.202301950

An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains

Author(s): Luigi Lerra, Martina Panatta, Dominik Bär, Isabella Zanini, Jennifer Yihong Tan, Agnese Pisano, Chiara Mungo, Célia Baroux, Vikram Govind Panse, Ana C. Marques, Raffaella Santoro
Published in: Molecular Cell, Issue 84, 2024, Page(s) 1667-1683.e10, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2024.03.015

PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency

Author(s): Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick GA Pedrioli, Martina Panatta, Michael O Hottiger, Paolo Cinelli, Raffaella Santoro
Published in: EMBO Reports, Issue 25, 2024, Page(s) 1453-1468, ISSN 1469-3178
Publisher: EMBO Reports
DOI: 10.1038/s44319-024-00083-z

Non-peer reviewed articles (3)

Single-cell dynamics of genome-nucleolus interactions captured by nucleolar laser microdissection (NoLMseq)

Author(s): Kaivalya Walavalkar, Shivani Gupta, Jelena Kresoja-Rakic, Mathieu Raingeval, Chiara Mungo, and Raffaella Santoro
Published in: bioRxiv, 2024, ISSN 2692-8205
Publisher: bioRxiv
DOI: 10.1101/2024.06.18.599512

NPM1 mediates genome-nucleolus interactions and the establishment of their repressive chromatin states

Author(s): Shivani Gupta, Cristiana Bersaglieri, Dominik Bär, Mathieu Raingeval, Luana Schaab, and Raffaella Santoro
Published in: bioRxiv, 2024, ISSN 2692-8205
Publisher: bioRxiv
DOI: 10.1101/2024.07.03.601885

Looking for a job in a dynamic and collaborative working place? LncRNAs are recruiting!

Author(s): Raffaella Santoro
Published in: Cell, 2021, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.10.020

Other (3)

PRAMEL7/CUL2 axis regulates NuRD stability to establish ground-state pluripotency in embryonic stem cells

Author(s): Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick G. A. Pedrioli, Martina Panatta, Michael O. Hottiger, Paolo Cinelli, Raffaella Santoro
Published in: bioRxiv, 2022
Publisher: Cold Spring Harbor Laboratory

BAZ2A-RNA mediated association with TOP2A and KDM1A represses gene expression in prostate cancer

Author(s): Marcin Roganowicz, Dominik Bär, Raffaella Santoro
Published in: bioRxiv, 2021
Publisher: Cold Spring Harbor Laboratory

Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains

Author(s): Cristiana Bersaglieri, Jelena Kresoja-Rakic, Shivani Gupta, Dominik Bär, Rostyslav Kuzyakiv, Raffaella Santoro
Published in: bioRxiv, 2020
Publisher: Cold Spring Harbor Laboratory

Monographic books (1)

Introduction to Epigenetics

Author(s): Renato Paro , Ueli Grossniklaus, Raffaella Santoro, Anton Wutz
Published in: 2021, ISBN 978-3-030-68670-3
Publisher: Springer International Publishing
DOI: 10.1007/978-3-030-68670-3