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How MHC-I editing complexes shape the hierarchical immune response

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Publications

MHC I assembly and peptide editing — chaperones, clients, and molecular plasticity in immunity

Author(s): Christoph Thomas, Robert Tampé
Published in: Current Opinion in Immunology, Issue 70, 2021, Page(s) 48-56, ISSN 0952-7915
DOI: 10.1016/j.coi.2021.02.004

Structural and Mechanistic Principles of ABC Transporters

Author(s): Christoph Thomas, Robert Tampé
Published in: Annual Review of Biochemistry, Issue 89/1, 2020, Page(s) 605-636, ISSN 0066-4154
DOI: 10.1146/annurev-biochem-011520-105201

Conformation space of a heterodimeric ABC exporter under turnover conditions

Author(s): Susanne Hofmann, Dovile Januliene, Ahmad R. Mehdipour, Christoph Thomas, Erich Stefan, Stefan Brüchert, Benedikt T. Kuhn, Eric R. Geertsma, Gerhard Hummer, Robert Tampé, Arne Moeller
Published in: Nature, Issue 571/7766, 2019, Page(s) 580-583, ISSN 0028-0836
DOI: 10.1038/s41586-019-1391-0

A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor

Author(s): Lina Sagert, Felix Hennig, Christoph Thomas, Robert Tampé
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
DOI: 10.7554/elife.55326

A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter

Author(s): Erich Stefan, Susanne Hofmann, Robert Tampé
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
DOI: 10.7554/elife.55943

Multifunctional Chaperone and Quality Control Complexes in Adaptive Immunity

Author(s): Simon Trowitzsch, Robert Tampé
Published in: Annual Review of Biophysics, Issue 49/1, 2020, ISSN 1936-122X
DOI: 10.1146/annurev-biophys-121219-081643