Stepping Up mRNA Mutanome Immunotherapy

Publicaciones

Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens

Autores: David Weber, Jonas Ibn-Salem, Patrick Sorn, Martin Suchan, Christoph Holtsträter, Urs Lahrmann, Isabel Vogler, Kathrin Schmoldt, Franziska Lang, Barbara Schrörs, Martin Löwer and Ugur Sahin
Publicado en: Nature Biotechnology, Edición 04-04-2022, 2022, ISSN 1087-0156
Editor: Nature Publishing Group
DOI: 10.1038/s41587-022-01247-9

Multiple instance learning to predict immune checkpoint blockade efficacy usingneoantigen candidates

Autores: Franziska Lang, Patrick Sorn, Barbara Schrörs, David Weber, Stefan Kramer, Ugur Sahin, Martin Löwer
Publicado en: iScience, Edición monthly, 2023, ISSN 2589-0042
Editor: iScience
DOI: 10.1016/j.isci.2023.108014

NeoFox: annotating neoantigen candidates with neoantigen features

Autores: Franziska Lang, Pablo Riesgo Ferreiro, Martin Löwer, Ugur Sahin, Barbara Schrörs
Publicado en: Bioinformatics, 2021, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1093/bioinformatics/btab344

Integrative analysis of structural variations using short-reads and linked-reads yields highly specific and sensitive predictions

Autores: Riccha Sethi, Julia Becker, Jos de Graaf, Martin Löwer, Martin Suchan, Ugur Sahin, David Weber
Publicado en: PLOS Computational Biology, Edición 16/11, 2020, Página(s) e1008397, ISSN 1553-7358
Editor: PLOS
DOI: 10.1371/journal.pcbi.1008397

Multi-Omics Characterization of the 4T1 Murine Mammary Gland Tumor Model

Autores: Barbara Schrörs, Sebastian Boegel, Christian Albrecht, Thomas Bukur, Valesca Bukur, Christoph Holtsträter, Christoph Ritzel, Katja Manninen, Arbel D. Tadmor, Mathias Vormehr, Ugur Sahin, Martin Löwer
Publicado en: Frontiers in Oncology, Edición 10, 2020, ISSN 2234-943X
Editor: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.01195

Identification of neoantigens for individualized therapeutic cancer vaccines

Autores: Franziska Lang, Barbara Schrörs, Martin Löwer, Özlem Türeci & Ugur Sahin
Publicado en: Nature Reviews Drug Discovery, Edición 01/02/2022, 2022, ISSN 1474-1776
Editor: Nature Publishing Group
DOI: 10.1038/s41573-021-00387-y

Prediction of tumor-specific splicing from somatic mutations as a source of neoantigen candidates

Autores: Franziska Lang, Patrick Sorn, Martin Suchan, Alina Henrich, Christian Albrecht, Nina Koehl, Aline Beicht, Pablo Riesgo-Ferreiro, Christoph Holtsträter, Barbara Schrörs, David Weber, Martin Löwer, Ugur Sahin, Jonas Ibn-Salem
Publicado en: biorxiv The preprint server for biology, 2023
Editor: biorxiv
DOI: 10.1101/2023.06.27.546494

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