iFERMENTER - CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROTEINS BY INTELLIGENT FERMENTATION | iFermenter | Project | Results | H2020 | CORDIS

Resultado final

Movie demonstration

External website of iFermenter open to the public, but also has secured login intranet pages to share secure internal information

Workshops RRI multi-actor dialogs

Workshops RRI multi-actor dialogs: White biotechnology and circular economy

Metabolic model, describing different physiological states of the cell factories

Metabolic model describing different physiological states of the cell factories

Genome network reduced dynamic mode
Process level reduced dynamic model

Initial Environmental impact assessment

Environmental impact assessment of the new strain, successfully demonstrating 20% reduction of CO2 in milliscales laboratory conditions

Developed (reduced) 3 models for the levels

Developed reduced 3 models for the levels genome metabolic and process Model predictions have satisfactory error margins 25 when compared to data D32 D34 D36

Successful demonstration of 20% reduction in CO2 footprint from the upscaled industrial process, by an LCA report

Successful demonstration of 20 reduction in CO2 footprint from the upscaled industrial process by an LCA report Environmental and demonstrating potential costs of upscaling the process O4b

Publicaciones

Recombinant production of the lantibiotic nisin using <i>Corynebacterium glutamicum</i> in a two-step process

Autores: Dominik Weixler; Max Berghoff; Kirill V. Ovchinnikov; Sebastian Reich; Oliver Goldbeck; Gerd M. Seibold; Christoph Wittmann; Nadav S. Bar; Bernhard J. Eikmanns; Dzung B. Diep; Christian U. Riedel
Publicado en: Microbial Cell Factories, Edición 1, 2022, ISSN 1475-2859
Editor: BioMed Central
DOI: 10.1186/s12934-022-01739-y

Sensor fusion based on Extended and Unscented Kalman Filter for bioprocess monitoring

Autores: Andrea Tuveri; Fernando Pérez-García; Pedro A. Lira-Parada; Lars Imsland; Nadav Bar
Publicado en: Journal of Process Control, Edición 2, 2021, ISSN 0959-1524
Editor: Butterworth Scientific Ltd.
DOI: 10.1016/j.jprocont.2021.09.005

Waste biorefinery towards a sustainable biotechnological production of pediocin: Synergy between process simulation and environmental assessment

Autores: Ana Arias, Daniel Barreiro, Gumersindo Feijoo, Maria Teresa Moreira
Publicado en: Environmental Technology & Innovation, Edición 26, 2022, ISSN 2352-1864
Editor: Elsevier BV
DOI: 10.1016/j.eti.2022.102306

Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum

Autores: Oliver Goldbeck, Dominique N. Desef, Kirill V. Ovchinnikov, Fernando Perez-Garcia, Jens Christmann, Peter Sinner, Peter Crauwels, Dominik Weixler, Peng Cao, Judith Becker, Michael Kohlstedt, Julian Kager, Bernhard J. Eikmanns, Gerd M. Seibold, Christoph Herwig, Christoph Wittmann, Nadav S. Bar, Dzung B. Diep, Christian U. Riedel
Publicado en: Metabolic Engineering, 2021, ISSN 1096-7176
Editor: Academic Press
DOI: 10.1016/j.ymben.2021.09.002

Inventory review and environmental evaluation of first- and second-generation sugars through life cycle assessment.

Autores: Sara Bello; Iana Salim; Gumersindo Feijoo; Maria Teresa Moreira
Publicado en: Environmental Science and Pollution Research, Edición 3, 2021, ISSN 0944-1344
Editor: Springer Verlag
DOI: 10.1007/s11356-021-12405-y

Dynamic Co-Cultivation Process of Corynebacterium glutamicum Strains for the Fermentative Production of Riboflavin

Autores: Fernando Pérez-García, Arthur Burgardt, Dina R. Kallman, Volker F. Wendisch, Nadav Bar
Publicado en: Fermentation, Edición 7/1, 2021, Página(s) 11, ISSN 2311-5637
Editor: MDPI
DOI: 10.3390/fermentation7010011

In Silico Prediction and Analysis of Unusual Lantibiotic Resistance Operons in the Genus Corynebacterium

Autores: Oliver Goldbeck, Dominik Weixler, Bernhard J. Eikmanns, Christian U. Riedel
Publicado en: Microorganisms, Edición 9/3, 2021, Página(s) 646, ISSN 2076-2607
Editor: MDPI
DOI: 10.3390/microorganisms9030646

Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being

Autores: Sabrina Wolf, Judith Becker, Yota Tsuge, Hideo Kawaguchi, Akihiko Kondo, Jan Marienhagen, Michael Bott, Volker F. Wendisch, Christoph Wittmann
Publicado en: Essays in Biochemistry, 2021, ISSN 0071-1365
Editor: Portland Press, Ltd.
DOI: 10.1042/ebc20200134

The use of maize stover and sugar beet pulp as feedstocks in industrial fermentation plants – An economic and environmental perspective

Autores: Iana Câmara-Salim; Pablo Conde; Gumersindo Feijoo; Maria Teresa Moreira
Publicado en: Cleaner Environmental Systems, Edición 3, 2021, ISSN 2666-7894
Editor: Elsevier
DOI: 10.1016/j.cesys.2020.100005

Technological feasibility and environmental assessment of polylactic acid-nisin-based active packaging.

Autores: Arias, A., Feijoo, G. & Moreira, M.T.
Publicado en: Sustainable Materials and Technologies, 2022, ISSN 2214-9937
Editor: Elsevier
DOI: 10.1016/j.susmat.2022.e00460

Linking process and metabolic modelling for the estimation of carbon flux distribution in Corynebacterium glutamicum growth in spent sulfite liquor

Autores: Pedro A.Lira-Parada, PeterSinner, MichaelKohlstedt, JulianKager, ChristophWittmann, ChristophHerwig, NadavBar
Publicado en: IFAC-PapersOnLine, 2022, ISSN 2405-8963
Editor: Elsevier
DOI: 10.1016/j.ifacol.2022.07.449

BECCS based on bioethanol from wood residues: Potential towards a carbon-negative transport and side-effects

Autores: Sara Bello, Ángel Galán-Martín, Gumersindo Feijoo, Maria Teresa Moreira, Gonzalo Guillén-Gosálbez
Publicado en: Applied Energy, Edición 279, 2020, Página(s) 115884, ISSN 0306-2619
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.apenergy.2020.115884

Noninvasive online monitoring of Corynebacterium glutamicum fed-batch bioprocesses subject to spent sulfite liquor raw material uncertainty

Autores: Peter Sinner, Marlene Stiegler, Christoph Herwig, Julian Kager
Publicado en: Bioresource Technology, Edición 321, 2021, Página(s) 124395, ISSN 0960-8524
Editor: Elsevier BV
DOI: 10.1016/j.biortech.2020.124395

The Increasing Issue of Vancomycin-Resistant Enterococci and the Bacteriocin Solution

Autores: Ingvild S. Reinseth, Kirill V. Ovchinnikov, Hanne H. Tønnesen, Harald Carlsen, Dzung B. Diep
Publicado en: Probiotics and Antimicrobial Proteins, 2019, ISSN 1867-1306
Editor: Springer Pub. Co.,
DOI: 10.1007/s12602-019-09618-6

Model-based Analysis and Optimisation of a Continuous Corynebacterium glutamicum Bioprocess Utilizing Lignocellulosic Waste

Autores: Peter Sinner, Julian Kager, Sven Daume, Christoph Herwig
Publicado en: IFAC-PapersOnLine, 2019, ISSN 2405-8963
Editor: Elsevier

The Industrial Organism Corynebacterium glutamicum Requires Mycothiol as Antioxidant to Resist Against Oxidative Stress in Bioreactor Cultivations

Autores: Fabian Stefan Franz Hartmann, Lina Clermont, Quach Ngoc Tung, Haike Antelmann, Gerd Michael Seibold
Publicado en: Antioxidants, Edición 9/10, 2020, Página(s) 969, ISSN 2076-3921
Editor: MDPI
DOI: 10.3390/antiox9100969

Establishing the multi-criteria roadmap and metrics for the evaluation of active films for food packaging

Autores: Arias, A., Feijoo, G., & Moreira, M. T.
Publicado en: Current Research in Green and Sustainable Chemistry, Edición 4, 2021, ISSN 2666-0865
Editor: Elsevier
DOI: 10.1016/j.crgsc.2021.100160

Process and environmental simulation in the validation of the biotechnological production of nisin from waste

Autores: Arias, A., Feijoo, G., & Moreira, M. T.
Publicado en: Biochemical Engineering Journal, Edición 174, 2021, ISSN 1369-703X
Editor: Elsevier BV
DOI: 10.1016/j.bej.2021.108105

Time Scale Analysis and Optimization of a Continuous Microbial Bioprocess

Autores: Peter Sinner, Christoph Herwig, Julian Kager
Publicado en: 30th European Symposium on Computer Aided Process Engineering, Edición 48, 2020, Página(s) 1603-1608, ISBN 9780128233771
Editor: Elsevier
DOI: 10.1016/b978-0-12-823377-1.50268-8

Usage of Digital Twins Along a Typical Process Development Cycle

Autores: Peter Sinner, Sven Daume, Christoph Herwig, Julian Kager
Publicado en: Digital Twins - Tools and Concepts for Smart Biomanufacturing, Edición 176, 2021, Página(s) 71-96, ISBN 978-3-030-71659-2
Editor: Springer International Publishing
DOI: 10.1007/10_2020_149

iFERMENTER - CONVERSION OF FORESTRY SUGAR RESIDUAL STREAMS TO ANTIMICROBIAL PROTEINS BY INTELLIGENT FERMENTATION

Resultado final

Publicaciones

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