The interoceptive link between anxiety and breathing perception

Información del proyecto

ILBAB

Identificador del acuerdo de subvención: 793580

DOI

10.3030/793580

Proyecto cerrado

Fecha de la firma de la CE 21 Marzo 2018

Fecha de inicio 1 Junio 2018

Fecha de finalización 31 Agosto 2020

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 175 419,60

Aportación de la UE

€ 175 419,60

Coordinado por

UNIVERSITAT ZURICH
Switzerland

Objetivo

Anxiety is one of the most common mental health issues, and debilitating anxiety symptoms can be present across a spectrum of diseases and disorders. While dysfunctional interoception (monitoring of the internal state of the body) is thought to be both a cause and effect of anxiety, the brain mechanisms leading to perturbed interoception remain unclear. Breathing offers a unique insight into our interoceptive processing, as the continuous swap between subconscious and conscious control provides an active gateway into our interoceptive selves. Therefore, this project aims to understand how anxiety may change the brain’s computations that underlie interoception of breathing, leading to identification of targets for treatments of debilitating anxiety symptoms across a range of physiological and psychiatric conditions. This proposal will employ interoceptive breathing tasks with high-resolution functional brain imaging, applying state-of-the-art computational models of perception to investigate where and how anxiety can interrupt brain processing systems. This project will utilise the inter-disciplinary strengths of the Translational Neuromodeling Unit (TNU) in Zurich, where computational research and applied psychological and clinical studies occur in tandem, and employ innovative and novel high-resolution scanning technologies available at the University of Zurich for unprecedented data quality. I will use my previous experience in high-field functional imaging of breathing perceptions, to develop and collect specific scanning protocols for high-resolution computational perception models. Here, I will target disparate anxiety groups within healthy volunteers, before future work moves towards applications in disease or disorder-specific populations. This work will occur within a wider framework of interoceptive research at the TNU, with the ultimate goal of providing novel diagnostic procedures and targeted treatments for symptoms of anxiety within an individual.

Palabras clave

• Breathing
• interoception
• anxiety

Programa(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions PROGRAMA PRINCIPAL
  
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
  

Tema(s)

• MSCA-IF-2017 - Individual Fellowships
  

Régimen de financiación

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Convocatoria de propuestas

H2020-MSCA-IF-2017

Coordinador

UNIVERSITAT ZURICH

• Aportación neta de la UEn: € 175 419,60
• Dirección: RAMISTRASSE 71 ; 8006 Zurich ; Suiza
• Región: Schweiz/Suisse/Svizzera › Zürich › Zürich
• Tipo de actividad: Higher or Secondary Education Establishments
• Coste total: € 175 419,60