3D bioprinting of pancreatic tissue for biomedical research

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Consortium website
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Consortium workshop II

Generation of a digital embryonic pancreas atlas

Dissemination WP3

Dissemination for WP3

Definition of each cell population in the pancreas
Deposing RNAseq datasets in public repositories

Protocol of printability conditions of pancreatic cells
Protocol of biomaterials for printing pancreatic cells
Generation of CAD files for 3D bio-printing

Publicaciones

Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions

Autores: Laura Glorieux, Aleksandra Sapala, David Willnow, Manon Moulis, Shlomit Edri, Jean-Francois Darrigrand, Anat Schonblum, Lina Sakhneny, Laura Schaumann, Harold F Gomez, Christine Lang, Lisa Conrad, Fabien Guillemot, Shulamit Levenberg, Limor Landsman, Dagmar Iber, Christophe Pierreux, Francesca M Spagnoli
Publicado en: bioRxiv, 2021, ISSN 2692-8205
Editor: Cold Spring Harbour Laboratories
DOI: 10.1101/2021.04.28.441857

Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system

Autores: David Willnow, Uwe Benary, Anca Margineanu, Maria Lillina Vignola, Igor M. Pongrac, Zahra Karimaddini, Alessandra Vigilante, Jana Wolf, Francesca M. Spagnoli
Publicado en: bioRxiv, 2020, ISSN 2692-8205
Editor: Cold Spring Harbour Laboratories
DOI: 10.1101/2020.08.06.240176

Single cell transcriptomic comparison between mouse embryonic pancreas and pancreatic organoids generated from mouse embryonic stem cell-derived mesoderm and pancreatic progenitors

Autores: Shlomit Edri, Vardit Rosenthal, Or Ginsburg, Abigail Newman Frisch, Christophe E. Pierreux, Nadav Sharon, Shulamit Levenberg
Publicado en: BioRxiv, Edición 26928205, 2022, ISSN 2692-8205
Editor: CSHL
DOI: 10.1101/2022.10.11.511696

Cell-based simulations of Notch-dependent cell differentiation on growing domains

Autores: Stopka Anna, Boareto do Amaral Marcelo, Iber Dagmar
Publicado en: bioRxiv, 2019, Página(s) 859363, ISSN 2692-8205
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/859363

Beta cell dysfunction in diabetes: the islet microenvironment as an unusual suspect

Autores: Joana Almaça, Alejandro Caicedo, Limor Landsman
Publicado en: Diabetologia, Edición 63/10, 2020, Página(s) 2076-2085, ISSN 0012-186X
Editor: Springer Verlag
DOI: 10.1007/s00125-020-05186-5

Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche

Autores: David Willnow, Uwe Benary , Anca Margineanu , Maria Lillina Vignola, Fabian Konrath, Igor M Pongrac, Zahra Karimaddini , Alessandra Vigilante, Jana Wolf, Francesca M Spagnoli
Publicado en: Nature, Edición 00280836, 2021, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-021-03844-1

The Role of Vascular Cells in Pancreatic Beta-Cell Function

Autores: Guzel Burganova, Claire Bridges, Peter Thorn, Limor Landsman
Publicado en: Frontiers in Endocrinology, Edición 12, 2021, ISSN 1664-2392
Editor: Frontiers Media SA
DOI: 10.3389/fendo.2021.667170

Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions

Autores: Laura Glorieux; Aleksandra Sapala; David Willnow; Manon Moulis; Anna Salowka; Jean-Francois Darrigrand; Shlomit Edri; Anat Schonblum; Lina Sakhneny; Laura Schaumann; Harold F. Gómez; Christine Lang; Lisa Conrad; Fabien Guillemot; Shulamit Levenberg; Limor Landsman; Dagmar Iber; Christophe E. Pierreux; Francesca M. Spagnoli
Publicado en: Development, Edición 09501991, 2022, ISSN 0950-1991
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dev.199655

Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming.

Autores: Abigail Isaacson; Francesca M. Spagnoli
Publicado en: Current Opinion in Genetics & Development, Edición 0959437X, 2021, ISSN 0959-437X
Editor: Elsevier BV
DOI: 10.1016/j.gde.2021.05.003

Pancreatic pericytes originate from the embryonic pancreatic mesenchyme

Autores: Neta Harari, Lina Sakhneny, Laura Khalifa-Malka, Anke Busch, Klemens J. Hertel, Matthias Hebrok, Limor Landsman
Publicado en: Developmental Biology, Edición 449/1, 2019, Página(s) 14-20, ISSN 0012-1606
Editor: Academic Press
DOI: 10.1016/j.ydbio.2019.01.020

Identification and implication of tissue-enriched ligands in epithelial–endothelial crosstalk during pancreas development

Autores: Manon Moulis; Steve Vincent Maurice Runser; Laura Glorieux; Nicolas Dauguet; Christophe Vanderaa; Laurent Gatto; Donatienne Tyteca; Patrick Henriet; Francesca M. Spagnoli; Dagmar Iber; Christophe E. Pierreux
Publicado en: Scientific Reports, Edición 20452322, 2022, Página(s) 12498, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-16072-y

A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation

Autores: Corinna Cozzitorto, Laura Mueller, Silvia Ruzittu, Nancy Mah, David Willnow, Jean-Francois Darrigrand, Heather Wilson, Daniel Khosravinia, Amir-Ala Mahmoud, Maurizio Risolino, Licia Selleri, Francesca M. Spagnoli
Publicado en: Developmental Cell, 2020, ISSN 1534-5807
Editor: Cell Press
DOI: 10.1016/j.devcel.2020.08.003

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