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3D bioprinting of pancreatic tissue for biomedical research

Deliverables

Generation of a digital embryonic pancreas atlas

Generation of a digital embryonic pancreas atlas

Definition of each cell population in the pancreas

Definition of each cell population in the pancreas

Deposing RNAseq datasets in public repositories

Deposing RNAseq datasets in public repositories

Protocol of printability conditions of pancreatic cells

Protocol of printability conditions of pancreatic cells

Protocol of biomaterials for printing pancreatic cells

Protocol of biomaterials for printing pancreatic cells

Generation of CAD files for 3D bio-printing

Generation of CAD files for 3D bio-printing

Searching for OpenAIRE data...

Publications

Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions

Author(s): Laura Glorieux, Aleksandra Sapala, David Willnow, Manon Moulis, Shlomit Edri, Jean-Francois Darrigrand, Anat Schonblum, Lina Sakhneny, Laura Schaumann, Harold F Gomez, Christine Lang, Lisa Conrad, Fabien Guillemot, Shulamit Levenberg, Limor Landsman, Dagmar Iber, Christophe Pierreux, Francesca M Spagnoli
Published in: bioRxiv, 2021, ISSN 2692-8205
DOI: 10.1101/2021.04.28.441857

Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system

Author(s): David Willnow, Uwe Benary, Anca Margineanu, Maria Lillina Vignola, Igor M. Pongrac, Zahra Karimaddini, Alessandra Vigilante, Jana Wolf,  Francesca M. Spagnoli
Published in: bioRxiv, 2020, ISSN 2692-8205
DOI: 10.1101/2020.08.06.240176

Cell-based simulations of Notch-dependent cell differentiation on growing domains

Author(s): Stopka Anna, Boareto do Amaral Marcelo, Iber Dagmar
Published in: bioRxiv, 2019, Page(s) 859363, ISSN 2692-8205
DOI: 10.1101/859363

Beta cell dysfunction in diabetes: the islet microenvironment as an unusual suspect

Author(s): Joana Almaça, Alejandro Caicedo, Limor Landsman
Published in: Diabetologia, Issue 63/10, 2020, Page(s) 2076-2085, ISSN 0012-186X
DOI: 10.1007/s00125-020-05186-5

The Role of Vascular Cells in Pancreatic Beta-Cell Function

Author(s): Guzel Burganova, Claire Bridges, Peter Thorn, Limor Landsman
Published in: Frontiers in Endocrinology, Issue 12, 2021, ISSN 1664-2392
DOI: 10.3389/fendo.2021.667170

Pancreatic pericytes originate from the embryonic pancreatic mesenchyme

Author(s): Neta Harari, Lina Sakhneny, Laura Khalifa-Malka, Anke Busch, Klemens J. Hertel, Matthias Hebrok, Limor Landsman
Published in: Developmental Biology, Issue 449/1, 2019, Page(s) 14-20, ISSN 0012-1606
DOI: 10.1016/j.ydbio.2019.01.020

A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation

Author(s): Corinna Cozzitorto, Laura Mueller, Silvia Ruzittu, Nancy Mah, David Willnow, Jean-Francois Darrigrand, Heather Wilson, Daniel Khosravinia, Amir-Ala Mahmoud, Maurizio Risolino, Licia Selleri, Francesca M. Spagnoli
Published in: Developmental Cell, 2020, ISSN 1534-5807
DOI: 10.1016/j.devcel.2020.08.003