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SIGNALING PROPENSITY IN THE MICROENVIRONMENT OF B CELL CHRONIC LYMPHOCYTIC LEUKEMIA

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Publications

IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3Kδ inhibitor idelalisib

Author(s): Veronika Sandova, Gabriela Mladonicka Pavlasova, Vaclav Seda, Katerina Amruz Cerna, Sonali Sharma, Veronika Palusova, Yvona Brychtova, Sarka Pospisilova, Stacey M. Fernandes, Anna Panovska, Michael Doubek, Matthew S. Davids, Jennifer R. Brown, Jiri Mayer, Marek Mraz
Published in: Haematologica, 2020, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2021.278644

Genetic and Non-Genetic Mechanisms of Resistance to BCR Signaling Inhibitors in B Cell Malignancies

Author(s): Laura Ondrisova, Marek Mraz
Published in: Frontiers in Oncology, 10, 2020, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2020.591577

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia

Author(s): Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja, Gabriela Mladonicka Pavlasova, Daniel Zicha, Marie Kudlickova Peskova, Jan Krivanek, Kvetoslava Liskova, Leos Kren, Vladimir Benes, Katerina Musilova Litzmanova, Marek Borsky, Jan Oppelt, Jan Verner, Sarka Pospisilova, Yvona Brychtova, Anna Panovska, Zhi Tan, Shuxing Zhang, Michael Doubek, Katerina Amruz Cerna
Published in: Blood, 138/9, 2021, Page(s) 758–772, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2020008101

miR-29 Modulates CD40 Signaling in Chronic Lymphocytic Leukemia by Targeting TRAF4: an Axis Affected by BCR inhibitors.

Author(s): Sonali Sharma, Gabriela Pavlasova, Vaclav Seda, Katerina Cerna, Eva Vojackova, Daniel Filip, Laura Ondrisova, Veronika Sandova, Lenka Kostalova, Pedro F. Zeni, Marek Borsky, Jan Oppelt, Kvetoslava Liskova, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic, Leos Kren, Andrea Janikova, Sarka Pospisilova, Stacey Marie Fernandes, Medhat Shehata, Laura Z. Rassen
Published in: Blood, 2020, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2020005627

The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy

Author(s): Gabriela Pavlasova, Marek Mraz
Published in: Haematologica, 105/6, 2020, Page(s) 1494-1506, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2019.243543