Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes

Información del proyecto

MORPHEUS

Identificador del acuerdo de subvención: 802736

DOI

10.3030/802736

Proyecto cerrado

Fecha de la firma de la CE 22 Octubre 2018

Fecha de inicio 1 Febrero 2019

Fecha de finalización 31 Octubre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 498 750,00

Aportación de la UE

€ 1 498 750,00

Coordinado por

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (22)

A type III polyketide synthase cluster in the phylum Planctomycetota is involved in alkylresorcinol biosynthesis

Autores: Lars Milke, Moses Kabuu, Renè Zschoche, Jochem Gätgens, Karin Krumbach, Kim-Loreen Carlstedt, Carmen E. Wurzbacher, Sven Balluff, Christine Beemelmanns, Christian Jogler, Jan Marienhagen & Nicolai Kallscheuer
Publicado en: Applied Microbiology and Biotechnology, 2023, Página(s) 239, ISSN 0175-7598
Editor: Springer Verlag
DOI: 10.1007/s00253-024-13065-x

Modular Solid-Phase Synthesis of Antiprotozoal Barnesin Derivatives

Autores: Dávid Roman, Luka Raguž, François Keiff, Florian Meyer, Fabian Barthels, Tanja Schirmeister, Florian Kloss, Christine Beemelmanns
Publicado en: Organic Letters, Edición 22/10, 2020, Página(s) 3744-3748, ISSN 1523-7060
Editor: American Chemical Society
DOI: 10.1021/acs.orglett.0c00723

Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor

Autores: Alexander U Bissel, Julia Rautschek , Sandra Hoefgen, Luka Raguž, Derek J Mattern, Nauman Saeed Slavica Janevska, Katarina Jojić, Ying Huang, Johann E Kufs, Barbara Herboeck , Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Publicado en: ACS Chem Biol, 2022, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.1c00839

Immunomodulatory function of antimicrobial peptide EC-Hepcidin1 modulates the induction of inflammatory gene expression in primary cells of Caspian Trout (Salmo trutta caspius Kessler, 1877)

Autores: Zohreh Ghodsi, Mohammad Reza Kalbassi, Parvaneh Farzaneh, Ashraf Mohebati Mobarez, Christine Beemelmanns, Jamshid Amiri Moghaddam
Publicado en: Fish & Shellfish Immunology, Edición 104, 2020, Página(s) 55-61, ISSN 1050-4648
Editor: Academic Press
DOI: 10.1016/j.fsi.2020.05.067

Recent highlights of biosynthetic studies on marine natural products

Autores: Jamshid Amiri Moghaddam, Theresa Jautzus, Mohammad Alanjary, Christine Beemelmanns
Publicado en: Organic & Biomolecular Chemistry, Edición 19/1, 2021, Página(s) 123-140, ISSN 1477-0520
Editor: Royal Society of Chemistry
DOI: 10.1039/d0ob01677b

Total Synthesis and Functional Evaluation of IORs, Sulfonolipid‐based Inhibitors of Cell Differentiation in<i>Salpingoeca rosetta</i>

Autores: Luka Raguž, Chia‐Chi Peng, Florentine U. N. Rutaganira, Thomas Krüger, Aleksa Stanišić, Theresa Jautzus, Hajo Kries, Olaf Kniemeyer, Axel A. Brakhage, Nicole King, Christine Beemelmanns
Publicado en: Angewandte Chemie, Edición 134, 2023, ISSN 0044-8249
Editor: Wiley
DOI: 10.1002/ange.202209105

Synthesis of Functionalized δ-Hydroxy-β-keto Esters and Evaluation of Their Anti-inflammatory Properties

Autores: Michel Grosse, Kerstin Günther, Paul M. Jordan, Dávid Roman, Oliver Werz, Christine Beemelmanns
Publicado en: ChemBioChem, 2022, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202200073

Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies

Autores: Maria Sauer, Andreas M. Kany, Sebastian Götze, Rolf Müller, Christine Beemelmanns
Publicado en: Angewandte Chemie International Edition, Edición 63, 2025, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202416036

Signalling molecules inducing metamorphosis in marine organisms.

Autores: Maja Rischer; Huijuan Guo; Christine Beemelmanns
Publicado en: Natural Product Reports, 2022, ISSN 0265-0568
Editor: Royal Society of Chemistry
DOI: 10.1039/d1np00073j

Applications of the Horner–Wadsworth–Emmons Olefination in Modern Natural Product Synthesis

Autores: Christine Beemelmanns, Dávid Roman, Maria Sauer
Publicado en: Synthesis, Edición 53/16, 2021, Página(s) 2713-2739, ISSN 0039-7881
Editor: Georg Thieme Verlag
DOI: 10.1055/a-1493-6331

Structural and Functional Analysis of Bacterial Sulfonosphingolipids and Rosette-Inducing Factor 2 (RIF-2) by Mass Spectrometry-Guided Isolation and Total Synthesis

Autores: Daniel Leichnitz, Chia-Chi Peng, Luka Raguž, Dr. Florentine U. N. Rutaganira, Theresa Jautzus, Dr. Lars Regestein, Prof. Nicole King, Dr. Christine Beemelmanns
Publicado en: Chemistry A European Journal, 2022, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202103883

An integrative understanding of the large metabolic shifts induced by antibiotics in critical illness

Autores: Andrea Marfil-Sánchez, Lu Zhang, Pol Alonso-Pernas, Mohammad Mirhakkak, Melinda Mueller, Bastian Seelbinder, Yueqiong Ni, Rakesh Santhanam, Anne Busch, Christine Beemelmanns, Maria Ermolaeva, Michael Bauer, Gianni Panagiotou
Publicado en: Gut Microbes, 2021, ISSN 1949-0976
Editor: Landes Bioscience
DOI: 10.1080/19490976.2021.1993598

Two Distinct Bacterial Biofilm Components Trigger Metamorphosis in the Colonial Hydrozoan Hydractinia echinata

Autores: Huijuan Guo, Maja Rischer, Martin Westermann, Christine Beemelmanns
Publicado en: mBio, Edición 12/3, 2021, ISSN 2150-7511
Editor: mBio
DOI: 10.1128/mbio.00401-21

DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data

Autores: Daniel Loos, Lu Zhang, Christine Beemelmanns, Oliver Kurzai, Gianni Panagiotou
Publicado en: Frontiers in Microbiology, Edición 12, 2021, ISSN 1664-302X
Editor: Frontiers Media
DOI: 10.3389/fmicb.2021.720513

Desaturation of the Sphingofungin Polyketide Tail Results in Increased Serine Palmitoyltransferase Inhibition.

Autores: Sandra Hoefgen; Alexander U. Bissell; Ying Huang; Fabio Gherlone; Luka Raguž; Christine Beemelmanns; Vito Valiante
Publicado en: Microbiology Spectrum, Edición 1, 2022, ISSN 2165-0497
Editor: American Society for Microbiology
DOI: 10.1128/spectrum.01331-22

Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis

Autores: Dávid Roman, Philippe Meisinger, Dr. Richard Guillonneau, Chia-Chi Peng, Lukas K. Peltner, Dr. Paul M. Jordan, Dr. Veit Haensch, Dr. Sebastian Götze, Prof. Oliver Werz, Prof. Christian Hertweck, Prof. Yin Chen, Prof. Christine Beemelmanns
Publicado en: Angew Chem Int Ed Engl, Edición weekly, 2024, Página(s) e202401195, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401195

From Persian Gulf to Indonesia: interrelated phylogeographic distance and chemistry within the genus Peronia (Onchidiidae, Gastropoda, Mollusca)

Autores: Fatemeh Maniei, Jamshid Amiri Moghaddam, Max Crüsemann, Christine Beemelmanns, Gabriele M. König, Heike Wägele
Publicado en: Scientific Reports, Edición 10/1, 2020, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-69996-8

Isolation of sulfonosphingolipids from the rosette-inducing bacterium <i>Zobellia uliginosa</i> and evaluation of their rosette-inducing activity

Autores: Chia-Chi Peng; Nils Dormanns; Lars Regestein; Christine Beemelmanns
Publicado en: Crossref, Edición 1, 2023, ISSN 2046-2069
Editor: Royal Society of Chemistry
DOI: 10.1039/d3ra04314b

Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of <i>anti</i>-1,2-amino alcohols

Autores: Maria Sauer; Christine Beemelmanns
Publicado en: Chemical Communication, 2022, Página(s) 8990-8993, ISSN 1364-548X
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc02317b

A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofungin A and C

Autores: Luka Raguž, Chia-Chi Peng, Dr. Marcel Kaiser, Dr. Helmar Görls, Dr. Christine Beemelmanns
Publicado en: Angew Chem Int Ed Engl, 2022, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202112616

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Autores: Mitja M Zdouc, Kai Blin, Nico L L Louwen, Jorge Navarro, Catarina Loureiro, Chantal D Bader, Constance B Bailey, Lena Barra, Thomas J Booth, Kenan A J Bozhüyük, José D D Cediel-Becerra, Zachary Charlop-Powers, Marc G Chevrette, Yit Heng Chooi, Paul M D’Agostino, Tristan de Rond, Elena Del Pup, Katherine R Duncan, Wenjia Gu, Novriyandi Hanif, Eric J N Helfrich, Matthew Jenner, Yoh
Publicado en: Nucleic Acids Research, Edición 53, 2025, Página(s) D678-D690, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkae1115

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity.

Autores: Jamshid Amiri Moghaddam; Huijuan Guo; Karsten Willing; Thomas Wichard; Christine Beemelmanns
Publicado en: Beilstein Journal of Organic Chemistry, 2022, Página(s) 722-731, ISSN 1860-5397
Editor: Beilstein-Institut
DOI: 10.3762/bjoc.18.72