Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes

Project Information

MORPHEUS

Grant agreement ID: 802736

DOI

10.3030/802736

Project closed

EC signature date 22 October 2018

Start date 1 February 2019

End date 31 October 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 498 750,00

EU contribution

€ 1 498 750,00

Coordinated by

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (22)

A type III polyketide synthase cluster in the phylum Planctomycetota is involved in alkylresorcinol biosynthesis

Author(s): Lars Milke, Moses Kabuu, Renè Zschoche, Jochem Gätgens, Karin Krumbach, Kim-Loreen Carlstedt, Carmen E. Wurzbacher, Sven Balluff, Christine Beemelmanns, Christian Jogler, Jan Marienhagen & Nicolai Kallscheuer
Published in: Applied Microbiology and Biotechnology, 2023, Page(s) 239, ISSN 0175-7598
Publisher: Springer Verlag
DOI: 10.1007/s00253-024-13065-x

Modular Solid-Phase Synthesis of Antiprotozoal Barnesin Derivatives

Author(s): Dávid Roman, Luka Raguž, François Keiff, Florian Meyer, Fabian Barthels, Tanja Schirmeister, Florian Kloss, Christine Beemelmanns
Published in: Organic Letters, Issue 22/10, 2020, Page(s) 3744-3748, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.0c00723

Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor

Author(s): Alexander U Bissel, Julia Rautschek , Sandra Hoefgen, Luka Raguž, Derek J Mattern, Nauman Saeed Slavica Janevska, Katarina Jojić, Ying Huang, Johann E Kufs, Barbara Herboeck , Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Published in: ACS Chem Biol, 2022, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.1c00839

Immunomodulatory function of antimicrobial peptide EC-Hepcidin1 modulates the induction of inflammatory gene expression in primary cells of Caspian Trout (Salmo trutta caspius Kessler, 1877)

Author(s): Zohreh Ghodsi, Mohammad Reza Kalbassi, Parvaneh Farzaneh, Ashraf Mohebati Mobarez, Christine Beemelmanns, Jamshid Amiri Moghaddam
Published in: Fish & Shellfish Immunology, Issue 104, 2020, Page(s) 55-61, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2020.05.067

Recent highlights of biosynthetic studies on marine natural products

Author(s): Jamshid Amiri Moghaddam, Theresa Jautzus, Mohammad Alanjary, Christine Beemelmanns
Published in: Organic & Biomolecular Chemistry, Issue 19/1, 2021, Page(s) 123-140, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0ob01677b

Total Synthesis and Functional Evaluation of IORs, Sulfonolipid‐based Inhibitors of Cell Differentiation in<i>Salpingoeca rosetta</i>

Author(s): Luka Raguž, Chia‐Chi Peng, Florentine U. N. Rutaganira, Thomas Krüger, Aleksa Stanišić, Theresa Jautzus, Hajo Kries, Olaf Kniemeyer, Axel A. Brakhage, Nicole King, Christine Beemelmanns
Published in: Angewandte Chemie, Issue 134, 2023, ISSN 0044-8249
Publisher: Wiley
DOI: 10.1002/ange.202209105

Synthesis of Functionalized δ-Hydroxy-β-keto Esters and Evaluation of Their Anti-inflammatory Properties

Author(s): Michel Grosse, Kerstin Günther, Paul M. Jordan, Dávid Roman, Oliver Werz, Christine Beemelmanns
Published in: ChemBioChem, 2022, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202200073

Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies

Author(s): Maria Sauer, Andreas M. Kany, Sebastian Götze, Rolf Müller, Christine Beemelmanns
Published in: Angewandte Chemie International Edition, Issue 63, 2025, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202416036

Signalling molecules inducing metamorphosis in marine organisms.

Author(s): Maja Rischer; Huijuan Guo; Christine Beemelmanns
Published in: Natural Product Reports, 2022, ISSN 0265-0568
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1np00073j

Applications of the Horner–Wadsworth–Emmons Olefination in Modern Natural Product Synthesis

Author(s): Christine Beemelmanns, Dávid Roman, Maria Sauer
Published in: Synthesis, Issue 53/16, 2021, Page(s) 2713-2739, ISSN 0039-7881
Publisher: Georg Thieme Verlag
DOI: 10.1055/a-1493-6331

Structural and Functional Analysis of Bacterial Sulfonosphingolipids and Rosette-Inducing Factor 2 (RIF-2) by Mass Spectrometry-Guided Isolation and Total Synthesis

Author(s): Daniel Leichnitz, Chia-Chi Peng, Luka Raguž, Dr. Florentine U. N. Rutaganira, Theresa Jautzus, Dr. Lars Regestein, Prof. Nicole King, Dr. Christine Beemelmanns
Published in: Chemistry A European Journal, 2022, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202103883

An integrative understanding of the large metabolic shifts induced by antibiotics in critical illness

Author(s): Andrea Marfil-Sánchez, Lu Zhang, Pol Alonso-Pernas, Mohammad Mirhakkak, Melinda Mueller, Bastian Seelbinder, Yueqiong Ni, Rakesh Santhanam, Anne Busch, Christine Beemelmanns, Maria Ermolaeva, Michael Bauer, Gianni Panagiotou
Published in: Gut Microbes, 2021, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2021.1993598

Two Distinct Bacterial Biofilm Components Trigger Metamorphosis in the Colonial Hydrozoan Hydractinia echinata

Author(s): Huijuan Guo, Maja Rischer, Martin Westermann, Christine Beemelmanns
Published in: mBio, Issue 12/3, 2021, ISSN 2150-7511
Publisher: mBio
DOI: 10.1128/mbio.00401-21

DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data

Author(s): Daniel Loos, Lu Zhang, Christine Beemelmanns, Oliver Kurzai, Gianni Panagiotou
Published in: Frontiers in Microbiology, Issue 12, 2021, ISSN 1664-302X
Publisher: Frontiers Media
DOI: 10.3389/fmicb.2021.720513

Desaturation of the Sphingofungin Polyketide Tail Results in Increased Serine Palmitoyltransferase Inhibition.

Author(s): Sandra Hoefgen; Alexander U. Bissell; Ying Huang; Fabio Gherlone; Luka Raguž; Christine Beemelmanns; Vito Valiante
Published in: Microbiology Spectrum, Issue 1, 2022, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.01331-22

Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis

Author(s): Dávid Roman, Philippe Meisinger, Dr. Richard Guillonneau, Chia-Chi Peng, Lukas K. Peltner, Dr. Paul M. Jordan, Dr. Veit Haensch, Dr. Sebastian Götze, Prof. Oliver Werz, Prof. Christian Hertweck, Prof. Yin Chen, Prof. Christine Beemelmanns
Published in: Angew Chem Int Ed Engl, Issue weekly, 2024, Page(s) e202401195, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401195

From Persian Gulf to Indonesia: interrelated phylogeographic distance and chemistry within the genus Peronia (Onchidiidae, Gastropoda, Mollusca)

Author(s): Fatemeh Maniei, Jamshid Amiri Moghaddam, Max Crüsemann, Christine Beemelmanns, Gabriele M. König, Heike Wägele
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-69996-8

Isolation of sulfonosphingolipids from the rosette-inducing bacterium <i>Zobellia uliginosa</i> and evaluation of their rosette-inducing activity

Author(s): Chia-Chi Peng; Nils Dormanns; Lars Regestein; Christine Beemelmanns
Published in: Crossref, Issue 1, 2023, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3ra04314b

Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of <i>anti</i>-1,2-amino alcohols

Author(s): Maria Sauer; Christine Beemelmanns
Published in: Chemical Communication, 2022, Page(s) 8990-8993, ISSN 1364-548X
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc02317b

A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofungin A and C

Author(s): Luka Raguž, Chia-Chi Peng, Dr. Marcel Kaiser, Dr. Helmar Görls, Dr. Christine Beemelmanns
Published in: Angew Chem Int Ed Engl, 2022, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202112616

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Author(s): Mitja M Zdouc, Kai Blin, Nico L L Louwen, Jorge Navarro, Catarina Loureiro, Chantal D Bader, Constance B Bailey, Lena Barra, Thomas J Booth, Kenan A J Bozhüyük, José D D Cediel-Becerra, Zachary Charlop-Powers, Marc G Chevrette, Yit Heng Chooi, Paul M D’Agostino, Tristan de Rond, Elena Del Pup, Katherine R Duncan, Wenjia Gu, Novriyandi Hanif, Eric J N Helfrich, Matthew Jenner, Yoh
Published in: Nucleic Acids Research, Issue 53, 2025, Page(s) D678-D690, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkae1115

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity.

Author(s): Jamshid Amiri Moghaddam; Huijuan Guo; Karsten Willing; Thomas Wichard; Christine Beemelmanns
Published in: Beilstein Journal of Organic Chemistry, 2022, Page(s) 722-731, ISSN 1860-5397
Publisher: Beilstein-Institut
DOI: 10.3762/bjoc.18.72