Deciphering Bacteria-induced Morphogenesis and Protection in marine Eukaryotes

Informazioni relative al progetto

MORPHEUS

ID dell’accordo di sovvenzione: 802736

DOI

10.3030/802736

Progetto chiuso

Data della firma CE 22 Ottobre 2018

Data di avvio 1 Febbraio 2019

Data di completamento 31 Ottobre 2024

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 498 750,00

Contributo UE

€ 1 498 750,00

Coordinato da

HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
Germany

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (22)

A type III polyketide synthase cluster in the phylum Planctomycetota is involved in alkylresorcinol biosynthesis

Autori: Lars Milke, Moses Kabuu, Renè Zschoche, Jochem Gätgens, Karin Krumbach, Kim-Loreen Carlstedt, Carmen E. Wurzbacher, Sven Balluff, Christine Beemelmanns, Christian Jogler, Jan Marienhagen & Nicolai Kallscheuer
Pubblicato in: Applied Microbiology and Biotechnology, 2023, Pagina/e 239, ISSN 0175-7598
Editore: Springer Verlag
DOI: 10.1007/s00253-024-13065-x

Modular Solid-Phase Synthesis of Antiprotozoal Barnesin Derivatives

Autori: Dávid Roman, Luka Raguž, François Keiff, Florian Meyer, Fabian Barthels, Tanja Schirmeister, Florian Kloss, Christine Beemelmanns
Pubblicato in: Organic Letters, Numero 22/10, 2020, Pagina/e 3744-3748, ISSN 1523-7060
Editore: American Chemical Society
DOI: 10.1021/acs.orglett.0c00723

Biosynthesis of the Sphingolipid Inhibitors Sphingofungins in Filamentous Fungi Requires Aminomalonate as a Metabolic Precursor

Autori: Alexander U Bissel, Julia Rautschek , Sandra Hoefgen, Luka Raguž, Derek J Mattern, Nauman Saeed Slavica Janevska, Katarina Jojić, Ying Huang, Johann E Kufs, Barbara Herboeck , Huijuan Guo, Falk Hillmann, Christine Beemelmanns, Vito Valiante
Pubblicato in: ACS Chem Biol, 2022, ISSN 1554-8929
Editore: American Chemical Society
DOI: 10.1021/acschembio.1c00839

Immunomodulatory function of antimicrobial peptide EC-Hepcidin1 modulates the induction of inflammatory gene expression in primary cells of Caspian Trout (Salmo trutta caspius Kessler, 1877)

Autori: Zohreh Ghodsi, Mohammad Reza Kalbassi, Parvaneh Farzaneh, Ashraf Mohebati Mobarez, Christine Beemelmanns, Jamshid Amiri Moghaddam
Pubblicato in: Fish & Shellfish Immunology, Numero 104, 2020, Pagina/e 55-61, ISSN 1050-4648
Editore: Academic Press
DOI: 10.1016/j.fsi.2020.05.067

Recent highlights of biosynthetic studies on marine natural products

Autori: Jamshid Amiri Moghaddam, Theresa Jautzus, Mohammad Alanjary, Christine Beemelmanns
Pubblicato in: Organic & Biomolecular Chemistry, Numero 19/1, 2021, Pagina/e 123-140, ISSN 1477-0520
Editore: Royal Society of Chemistry
DOI: 10.1039/d0ob01677b

Total Synthesis and Functional Evaluation of IORs, Sulfonolipid‐based Inhibitors of Cell Differentiation in<i>Salpingoeca rosetta</i>

Autori: Luka Raguž, Chia‐Chi Peng, Florentine U. N. Rutaganira, Thomas Krüger, Aleksa Stanišić, Theresa Jautzus, Hajo Kries, Olaf Kniemeyer, Axel A. Brakhage, Nicole King, Christine Beemelmanns
Pubblicato in: Angewandte Chemie, Numero 134, 2023, ISSN 0044-8249
Editore: Wiley
DOI: 10.1002/ange.202209105

Synthesis of Functionalized δ-Hydroxy-β-keto Esters and Evaluation of Their Anti-inflammatory Properties

Autori: Michel Grosse, Kerstin Günther, Paul M. Jordan, Dávid Roman, Oliver Werz, Christine Beemelmanns
Pubblicato in: ChemBioChem, 2022, ISSN 1439-4227
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202200073

Structure Revision of Halisphingosine A via Total Synthesis and Bioactivity Studies

Autori: Maria Sauer, Andreas M. Kany, Sebastian Götze, Rolf Müller, Christine Beemelmanns
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2025, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202416036

Signalling molecules inducing metamorphosis in marine organisms.

Autori: Maja Rischer; Huijuan Guo; Christine Beemelmanns
Pubblicato in: Natural Product Reports, 2022, ISSN 0265-0568
Editore: Royal Society of Chemistry
DOI: 10.1039/d1np00073j

Applications of the Horner–Wadsworth–Emmons Olefination in Modern Natural Product Synthesis

Autori: Christine Beemelmanns, Dávid Roman, Maria Sauer
Pubblicato in: Synthesis, Numero 53/16, 2021, Pagina/e 2713-2739, ISSN 0039-7881
Editore: Georg Thieme Verlag
DOI: 10.1055/a-1493-6331

Structural and Functional Analysis of Bacterial Sulfonosphingolipids and Rosette-Inducing Factor 2 (RIF-2) by Mass Spectrometry-Guided Isolation and Total Synthesis

Autori: Daniel Leichnitz, Chia-Chi Peng, Luka Raguž, Dr. Florentine U. N. Rutaganira, Theresa Jautzus, Dr. Lars Regestein, Prof. Nicole King, Dr. Christine Beemelmanns
Pubblicato in: Chemistry A European Journal, 2022, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202103883

An integrative understanding of the large metabolic shifts induced by antibiotics in critical illness

Autori: Andrea Marfil-Sánchez, Lu Zhang, Pol Alonso-Pernas, Mohammad Mirhakkak, Melinda Mueller, Bastian Seelbinder, Yueqiong Ni, Rakesh Santhanam, Anne Busch, Christine Beemelmanns, Maria Ermolaeva, Michael Bauer, Gianni Panagiotou
Pubblicato in: Gut Microbes, 2021, ISSN 1949-0976
Editore: Landes Bioscience
DOI: 10.1080/19490976.2021.1993598

Two Distinct Bacterial Biofilm Components Trigger Metamorphosis in the Colonial Hydrozoan Hydractinia echinata

Autori: Huijuan Guo, Maja Rischer, Martin Westermann, Christine Beemelmanns
Pubblicato in: mBio, Numero 12/3, 2021, ISSN 2150-7511
Editore: mBio
DOI: 10.1128/mbio.00401-21

DAnIEL: A User-Friendly Web Server for Fungal ITS Amplicon Sequencing Data

Autori: Daniel Loos, Lu Zhang, Christine Beemelmanns, Oliver Kurzai, Gianni Panagiotou
Pubblicato in: Frontiers in Microbiology, Numero 12, 2021, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2021.720513

Desaturation of the Sphingofungin Polyketide Tail Results in Increased Serine Palmitoyltransferase Inhibition.

Autori: Sandra Hoefgen; Alexander U. Bissell; Ying Huang; Fabio Gherlone; Luka Raguž; Christine Beemelmanns; Vito Valiante
Pubblicato in: Microbiology Spectrum, Numero 1, 2022, ISSN 2165-0497
Editore: American Society for Microbiology
DOI: 10.1128/spectrum.01331-22

Structure Revision of a Widespread Marine Sulfonolipid Class Based on Isolation and Total Synthesis

Autori: Dávid Roman, Philippe Meisinger, Dr. Richard Guillonneau, Chia-Chi Peng, Lukas K. Peltner, Dr. Paul M. Jordan, Dr. Veit Haensch, Dr. Sebastian Götze, Prof. Oliver Werz, Prof. Christian Hertweck, Prof. Yin Chen, Prof. Christine Beemelmanns
Pubblicato in: Angew Chem Int Ed Engl, Numero weekly, 2024, Pagina/e e202401195, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401195

From Persian Gulf to Indonesia: interrelated phylogeographic distance and chemistry within the genus Peronia (Onchidiidae, Gastropoda, Mollusca)

Autori: Fatemeh Maniei, Jamshid Amiri Moghaddam, Max Crüsemann, Christine Beemelmanns, Gabriele M. König, Heike Wägele
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-69996-8

Isolation of sulfonosphingolipids from the rosette-inducing bacterium <i>Zobellia uliginosa</i> and evaluation of their rosette-inducing activity

Autori: Chia-Chi Peng; Nils Dormanns; Lars Regestein; Christine Beemelmanns
Pubblicato in: Crossref, Numero 1, 2023, ISSN 2046-2069
Editore: Royal Society of Chemistry
DOI: 10.1039/d3ra04314b

Application of pyrrolo-protected amino aldehydes in the stereoselective synthesis of <i>anti</i>-1,2-amino alcohols

Autori: Maria Sauer; Christine Beemelmanns
Pubblicato in: Chemical Communication, 2022, Pagina/e 8990-8993, ISSN 1364-548X
Editore: Royal Society of Chemistry
DOI: 10.1039/d2cc02317b

A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofungin A and C

Autori: Luka Raguž, Chia-Chi Peng, Dr. Marcel Kaiser, Dr. Helmar Görls, Dr. Christine Beemelmanns
Pubblicato in: Angew Chem Int Ed Engl, 2022, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202112616

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Autori: Mitja M Zdouc, Kai Blin, Nico L L Louwen, Jorge Navarro, Catarina Loureiro, Chantal D Bader, Constance B Bailey, Lena Barra, Thomas J Booth, Kenan A J Bozhüyük, José D D Cediel-Becerra, Zachary Charlop-Powers, Marc G Chevrette, Yit Heng Chooi, Paul M D’Agostino, Tristan de Rond, Elena Del Pup, Katherine R Duncan, Wenjia Gu, Novriyandi Hanif, Eric J N Helfrich, Matthew Jenner, Yoh
Pubblicato in: Nucleic Acids Research, Numero 53, 2025, Pagina/e D678-D690, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkae1115

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity.

Autori: Jamshid Amiri Moghaddam; Huijuan Guo; Karsten Willing; Thomas Wichard; Christine Beemelmanns
Pubblicato in: Beilstein Journal of Organic Chemistry, 2022, Pagina/e 722-731, ISSN 1860-5397
Editore: Beilstein-Institut
DOI: 10.3762/bjoc.18.72