Characterisation of T cell diversity
T cells constitute an important part of adaptive immunity against pathogens and comprise different populations with different functions. Identification of these T cell subsets usually relies on the expression of surface antigens including CD4+ and CD8+. However, we lack basic understanding of the functional diversity of T cells at the single-cell level. The key objective of the EU-funded FunDiT project is to characterise the gene expression profile and identify key pathways in single T cells. Project results will help determine the role of different T cell subsets in the immune response.
Fields of science
Funding SchemeERC-STG - Starting Grant
142 20 Praha 4
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