Periodic Reporting for period 2 - WHILYAS (Wound healing ILYA-style)
Período documentado: 2018-12-01 hasta 2019-08-31
The first indication targeted with a large unmet medical need is accelerated healing of large and chronic wounds. Wounds, acute and chronic, entail a huge distress for people and the disrupted barrier is an immediate window for microbes. Small wounds becoming chronic is particularly problematic for people with underlying pathologies that both increase the susceptibility for acquiring wounds as well as reduce healing abilities. Diabetes is one of such pathologies. The occurrence of foot ulcers, or a history thereof, means a 14 years reduction in lifetime expectancy.
In this WHILYAS (Wound Healing Ilya Style) project the objectives are to accelerate development of the drug candidate ILP100 through toxicity testing in large animal models, GMP-manufacturing, a first in human clinical study and outlining a strategic development program forward. The objectives for ILP100 is to heal difficult and chronic wounds in patients with diabetes in a better, faster and more cost-efficient manner than any other drug or medical device available today or in pipeline.
Due to the long lead times in drug development the impact has not yet reached the patients. Though the currently available devices have been mapped in the different market and care segments as well as the current global pipeline of medical products in clinical trials. With this information and the non-clinical data available cases of health economics and reimbursement models have been initiated to understand the full societal impact of the product, once approved and used.
Ilya Pharma is now in a Series A/mid-financing investment round to finance two phase II clinical trials in different wound indications as well as consequent regulatory and commercial activities. The activities in the WHILYAS project are key to the future execution plan and ability to secure financing.