Skip to main content

Targeted microbubble vibrations to accurately diagnose and treat cardiac device-related bacterial biofilm infections

Project description

Towards accurate diagnosis and treatment of cardiac device-related bacterial infections

Because of the world’s ageing population, more and more cardiac devices are being implanted. However, life-threatening bacterial infections can occur on these devices. Currently, such infections are mainly diagnosed using ultrasound imaging. Unfortunately, this method is not specific or sensitive enough, making accurate diagnoses challenging. A targeted, non-invasive treatment is also desperately needed, but currently unavailable because of the complex disease. Advanced ultrasound imaging and therapy using targeted ultrasound contrast agents called targeted microbubbles to detect and treat bacterial infections is needed to solve the challenges. Building on previous research on targeted microbubbles, the EU-funded BUBBLE CURE project aims to develop innovative detection, analysis and modelling methods to accurately determine which tMB vibrations are needed to diagnose and eradicate bacterial biofilm infections on cardiac devices. The project’s achievements will enable precise diagnosis and treatment of cardiac device-related bacterial biofilm infections.

Host institution

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Net EU contribution
€ 1 878 000,00
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Netherlands

See on map

Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 878 000,00

Beneficiaries (1)

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
Net EU contribution
€ 1 878 000,00
Address
Dr Molewaterplein 40
3015 GD Rotterdam

See on map

Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 878 000,00