Project description
Towards accurate diagnosis and treatment of cardiac device-related bacterial infections
Because of the world’s ageing population, more and more cardiac devices are being implanted. However, life-threatening bacterial infections can occur on these devices. Currently, such infections are mainly diagnosed using ultrasound imaging. Unfortunately, this method is not specific or sensitive enough, making accurate diagnoses challenging. A targeted, non-invasive treatment is also desperately needed, but currently unavailable because of the complex disease. Advanced ultrasound imaging and therapy using targeted ultrasound contrast agents called targeted microbubbles to detect and treat bacterial infections is needed to solve the challenges. Building on previous research on targeted microbubbles, the EU-funded BUBBLE CURE project aims to develop innovative detection, analysis and modelling methods to accurately determine which tMB vibrations are needed to diagnose and eradicate bacterial biofilm infections on cardiac devices. The project’s achievements will enable precise diagnosis and treatment of cardiac device-related bacterial biofilm infections.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
ERC-STG - Starting Grant
Host institution
3015 GD Rotterdam
Netherlands
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Beneficiaries (1)
3015 GD Rotterdam
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