Skip to main content

Overcoming specific weaknesses in tendon biology to design advanced regenerative therapies

Deliverables

Publications

Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation

Author(s): A.I. Gonçalves, M. Rotherham, H. Markides, M.T. Rodrigues, R.L. Reis, M.E. Gomes, A.J. El Haj
Published in: Nanomedicine: Nanotechnology, Biology and Medicine, Issue 14/4, 2018, Page(s) 1149-1159, ISSN 1549-9634
DOI: 10.1016/j.nano.2018.02.008

The effects of platelet lysate patches on the activity of tendon-derived cells

Author(s): Raquel Costa-Almeida, Albina R. Franco, Tamagno Pesqueira, Mariana B. Oliveira, Pedro S. Babo, Isabel B. Leonor, João F. Mano, Rui L. Reis, Manuela E. Gomes
Published in: Acta Biomaterialia, Issue 68, 2018, Page(s) 29-40, ISSN 1742-7061
DOI: 10.1016/j.actbio.2018.01.006

Cell-laden composite suture threads for repairing damaged tendons

Author(s): Raquel Costa-Almeida, Rui M.A. Domingues, Afsoon Fallahi, Huseyin Avci, Iman K. Yazdi, Mohsen Akbari, Rui L. Reis, Ali Tamayol, Manuela E. Gomes, Ali Khademhosseini
Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 12/4, 2018, Page(s) 1039-1048, ISSN 1932-6254
DOI: 10.1002/term.2605

Tissue-engineered magnetic cell sheet patches for advanced strategies in tendon regeneration

Author(s): Ana I. Gonçalves, Márcia T. Rodrigues, Manuela E. Gomes
Published in: Acta Biomaterialia, Issue 63, 2017, Page(s) 110-122, ISSN 1742-7061
DOI: 10.1016/j.actbio.2017.09.014

Multifunctional magnetic-responsive hydrogels to engineer tendon-to-bone interface

Author(s): Elsa D. Silva, Pedro S. Babo, Raquel Costa-Almeida, Rui M.A. Domingues, Bárbara B. Mendes, Elvira Paz, Paulo Freitas, Márcia T. Rodrigues, Pedro L. Granja, Manuela E. Gomes
Published in: Nanomedicine: Nanotechnology, Biology and Medicine, Issue 14/7, 2018, Page(s) 2375-2385, ISSN 1549-9634
DOI: 10.1016/j.nano.2017.06.002

Human adipose tissue-derived tenomodulin positive subpopulation of stem cells: A promising source of tendon progenitor cells

Author(s): A.I. Gonçalves, P.M. Gershovich, M.T. Rodrigues, R.L. Reis, M.E. Gomes
Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 12/3, 2018, Page(s) 762-774, ISSN 1932-6254
DOI: 10.1002/term.2495

In vitro and in vivo assessment of magnetically actuated biomaterials and prospects in tendon healing

Author(s): Lívia Santos, Marta Silva, Ana I. Gonçalves, Tamagno Pesqueira, Márcia T. Rodrigues, Manuela E. Gomes
Published in: Nanomedicine, Issue 11/9, 2016, Page(s) 1107-1122, ISSN 1743-5889
DOI: 10.2217/nnm-2015-0014

3D Mimicry of Native-Tissue-Fiber Architecture Guides Tendon-Derived Cells and Adipose Stem Cells into Artificial Tendon Constructs

Author(s): Mariana Laranjeira, Rui M. A. Domingues, Raquel Costa-Almeida, Rui L. Reis, Manuela E. Gomes
Published in: Small, Issue 13/31, 2017, Page(s) 1700689, ISSN 1613-6810
DOI: 10.1002/smll.201700689

Exploring the Potential of Starch/Polycaprolactone Aligned Magnetic Responsive Scaffolds for Tendon Regeneration

Author(s): Ana I. Gonçalves, Márcia T. Rodrigues, Pedro P. Carvalho, Manuel Bañobre-López, Elvira Paz, Paulo Freitas, Manuela E. Gomes
Published in: Advanced Healthcare Materials, Issue 5/2, 2016, Page(s) 213-222, ISSN 2192-2640
DOI: 10.1002/adhm.201500623

Enhancing the Biomechanical Performance of Anisotropic Nanofibrous Scaffolds in Tendon Tissue Engineering: Reinforcement with Cellulose Nanocrystals

Author(s): Rui M. A. Domingues, Silvia Chiera, Pavel Gershovich, Antonella Motta, Rui L. Reis, Manuela E. Gomes
Published in: Advanced Healthcare Materials, Issue 5/11, 2016, Page(s) 1364-1375, ISSN 2192-2640
DOI: 10.1002/adhm.201501048

Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose‐derived stem cells

Author(s): Ana I. Gonçalves, Dominika Berdecka, Márcia T. Rodrigues, Aysegul Dede Eren, Jan Boer, Rui L. Reis, Manuela E. Gomes
Published in: Journal of Tissue Engineering and Regenerative Medicine, Issue 13/12, 2019, Page(s) 2204-2217, ISSN 1932-6254
DOI: 10.1002/term.2967

Mesenchymal Stem Cells Empowering Tendon Regenerative Therapies

Author(s): Raquel Costa-Almeida, Isabel Calejo, Manuela E. Gomes
Published in: International Journal of Molecular Sciences, Issue 20/12, 2019, Page(s) 3002, ISSN 1422-0067
DOI: 10.3390/ijms20123002

Biphasic Hydrogels Integrating Mineralized and Anisotropic Features for Interfacial Tissue Engineering

Author(s): Mari Carmen Echave, Rui M. A. Domingues, Manuel Gómez-Florit, José Luis Pedraz, Rui L. Reis, Gorka Orive, Manuela E. Gomes
Published in: ACS Applied Materials & Interfaces, Issue 11/51, 2019, Page(s) 47771-47784, ISSN 1944-8244
DOI: 10.1021/acsami.9b17826

Magnetic biomaterials and nano-instructive tools as mediators of tendon mechanotransduction

Author(s): Ana M. Matos, Ana I. Gonçalves, Alicia J. El Haj, Manuela E. Gomes
Published in: Nanoscale Advances, Issue 2/1, 2020, Page(s) 140-148, ISSN 2516-0230
DOI: 10.1039/c9na00615j

TENDON REGENERATION: Understanding Tissue Physiology and Development to Engineer Functional Substitutes

Author(s): Gomes M. E., Reis R. L., and Rodrigues M. T. (eds)
Published in: 2015, Page(s) iii
DOI: 10.1016/B978-0-12-801590-2.01001-2

Biomaterials as Tendon and Ligament Substitutes: Current Developments

Author(s): Mariana L. Santos, Márcia T. Rodrigues, Rui M. A. Domingues, Rui Luís Reis, Manuela E. Gomes
Published in: Regenerative Strategies for the Treatment of Knee Joint Disabilities, Issue 21/17, 2016, Page(s) 349-371
DOI: 10.1007/978-3-319-44785-8_17

Bioengineered Strategies for Tendon Regeneration

Author(s): A.I. Gonçalves, M.T. Rodrigues, R.L. Reis, M.E. Gomes
Published in: In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design, 2016, Page(s) 275-293
DOI: 10.1016/B978-0-12-802225-2.00015-5

Fabrication of Hierarchical and Biomimetic Fibrous Structures to Support the Regeneration of Tendon Tissues

Author(s): Rui M.A. Domingues, Ana I. Gonçalves, Raquel Costa-Almeida, Márcia T. Rodrigues, Rui L. Reis, Manuela E. Gomes
Published in: Tendon Regeneration, 2015, Page(s) 259-280
DOI: 10.1016/B978-0-12-801590-2.00010-7

Cell-Based Approaches for Tendon Regeneration

Author(s): Ana I. Gonçalves, Raquel Costa-Almeida, Pavel Gershovich, Márcia T. Rodrigues, Rui L. Reis, Manuela E. Gomes
Published in: Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes, 2015, Page(s) 187-203
DOI: 10.1016/B978-0-12-801590-2.00006-5

Designing microenvironments for optimal outcomes in tissue engineering and regenerative medicine: From biopolymers to culturing conditions

Author(s): Tsiapalis D, Ribeiro S, De Pieri A, Sallent I, Guillaumin S, Gaspar D, Korntner, S, Bayon, Y, Gomes, M E, Reis, R L, Zeugolis, D I
Published in: Encyclopedia of Tissue Engineering and Regenerative Medicine, 2019, Page(s) 119-30

DESIGN AND CHARACTERIZATION OF SYNTHETIC BIODEGRADABLE FILMS FOR MUSCULOSKELETAL TISSUE ENGINEERING

Author(s): S. Ribeiro, V. Novacek, E.M. Fernandes, M.E. Gomes, R.L. Reis, Y. Bayon, D.I. Zeugolis
Published in: The Bone & Joint Journal/Orthopaedic Proceedings, 2018, ISSN 2049-4416