Strengthening Omics data analysis capacities in pathogen-host interaction

Información del proyecto

PHINDaccess

Identificador del acuerdo de subvención: 811034

DOI

10.3030/811034

Proyecto cerrado

Fecha de la firma de la CE 8 Junio 2018

Fecha de inicio 1 Octubre 2018

Fecha de finalización 30 Septiembre 2022

Financiado con arreglo a

• Twinning of research institutions

Coste total

€ 989 468,75

Aportación de la UE

€ 989 468,70

Coordinado por

INSTITUT PASTEUR DE TUNIS
Tunisia

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (1)

Data Management Plan

Documents, reports (3)

Promotional activities, dissemination and communication plan

The promotional activities involve first the set up of web site which will include information about the project, partners, promoted activities, achieved results, and links to the materials produced (e.g. news, information related to the project, reports, kits, etc.). The website will be an interactive and visual portal responding to the needs of the different WP’s and audiences. It will be designed to respond to expressed needs of targeted audiences. Secondly, social media will be exploited such us the production of small science awareness videos with IPT’s research scientists. We will benefit from the expertise and experience of IP and CRG partners. PHINDaccess will also develop several accounts on social networks (linkedin, twitter, facebook, youtube, etc.) to reach the different audiences and create communities around the project.

Course program descriptive booklet

Overall, task 2.1 will allow the participants to master all regulatory and ethical constraints related to biobanking and data stewardship. (D2.1)

List of training/networking sessions

This task will complement WP2 objectives and enhance the expertise and skills of young and experienced investigators in Omics applied to strategic PHI models (section 1.3.4.3). An extensive networking program will be implemented to foster the development of innovative approaches in key PHI models (section 1.3.4.3). This program will include two-way lab visits between IPT’s research units and those from the partnering institutions, joint workshops and hackathons (WP2) on advanced processing, analysis and mining of Omics data and computational modeling of PHI biological circuits. A list of training/networking sessions of interest will be drafted in M6 (D4.2).

Websites, patent fillings, videos etc. (1)

An optimized computational environment for efficient and secured Omics data analysis

Task 3.1 Setting up a reliable and highly efficient environment for Omics data stewardship This task aims at creating a highly efficient environment for Omics data management. IPT will pair with RKI, CRG and IP todevise an adapted strategy for data management with respect to interoperability, security, confidentiality and backup in compliance with the FAIR data principles and the H2020 vision. This will give rise to a dedicated platform to achieve this (D3.1).

Publicaciones

Peer reviewed articles (5)

Identification of two novel hepatitis C virus subtype 2 from Tunisia (2v and 2w)

Autores: Mouna Rajhi, Sondes Haddad-Boubaker, Anissa Chouikha, Daniel Bourquain, Janine Michel, Walid Hammami, Amel Sadraoui, Hinda Touzi, Kais Ghedira, Henda Triki
Publicado en: PLOS ONE, 2021, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0248249

In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect.

Autores: Sondes Haddad-Boubaker; Houcemeddine Othman; Rabeb Touati; Kaouther Ayouni; Marwa Lakhal; Imen Ben Mustapha; Kais Ghedira; Maher Kharrat; Henda Triki
Publicado en: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-14 (2021), 2022, ISSN 2296-889X
Editor: FRONTIERS MEDIA SA
DOI: 10.1186/s12859-021-04045-3

ConsensusPathDB 2022: molecular interactions update as a resource for network biology

Autores: Atanas Kamburov, Ralf Herwig
Publicado en: Nucleic Acids Research, 2022, Página(s) Pages D587–D595, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkab1128

An Integrative Computational Approach for the Prediction of Human-Plasmodium Protein-Protein Interactions

Autores: Kais Ghedira, Yosr Hamdi, Abir El Béji, Houcemeddine Othman
Publicado en: BioMed Research International, 2020, ISSN 2314-6133
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2020/2082540

Longitudinal and comparative analysis of Tunisian newborns gut microbiota according to delivery mode

Autores: Mariem Hanachi, Olfa Maghrebi, Haifa Bichiou, Ferdaous Trabelsi, Najla Maha Bouyahia, Fethi Zhioua, Meriam Belghith, Emna Harigua-Souiai, Meriem Baouendi, Lamia Guizani-Tabbane, Alia Benkahla, Oussema Souiai
Publicado en: Frontiers in Microbiology, 2022, ISSN 1664-302X
Editor: Frontiers Media
DOI: 10.3389/fmicb.2022.780568