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Biomechanics in health and disease: advanced physical tools for innovative early diagnosis

Descripción del proyecto

Nuevos marcadores biomecánicos para un diagnóstico precoz

Hace tiempo que se ha demostrado que la mecánica de las células está relacionada con diversas enfermedades y afecciones. El objetivo del proyecto Phys2BioMed, financiado por las Acciones Marie Skłodowska-Curie, es identificar y establecer marcadores biomecánicos para la detección precoz de disfunciones celulares y tisulares en la fase inicial de la enfermedad. La finalidad es crear una red interdisciplinar de formación en investigación para investigadores noveles sobre la aplicación de herramientas físicas para el fenotipado mecánico de células y tejidos, desarrollando así nuevos diagnósticos precoces. La red combinará la formación de diversos campos, como la nanociencia y la nanotecnología, la física, la biología y la medicina, lo que permitirá definir las principales características del instrumental de nueva generación optimizado para el fenotipado mecánico de los materiales clínicos.

Objetivo

Phys2BioMed will offer excellent interdisciplinary and cross-sectoral training to a team of motivated early stage researchers (ESRs) on the application of cutting-edge physical tools for the mechanical phenotyping of cells and tissues of clinical relevance, aiming at developing novel early-diagnostic tools. The Phys2BioMed network will merge diverse competences at European level, from different fields like nanoscience and nanotechnology, physics, biology, and medicine, and will expose ESRs to the non academic and private sector. A key element of the project is the peer-to-peer collaboration of research academic institutions with industries and world-leading medical and clinical centers; these are the main actors of the global challenge against diseases, and within Phys2BioMed they will highlight unmet clinical needs, and actively cooperate with academic colleagues for developing novel diagnostic strategies. ESRs will be trained-through-research by world-leading junior and senior PIs, and will benefit of lecture courses, dedicated international schools and workshops, and topical conferences. Secondments to other nodes of the network will represent the main and more effective channel of dissemination and cross-fertilization of competences, ideas, and knowledge within the network. Besides training talented young scientists, ready to work at the boundary of diverse disciplines in the field of nanomedicine, Phys2BioMed will provide scientific and technological outcomes on biomechanics, and the mechanical determinants of diseases. Technology-wise, it will define standardized procedures for nanomechanical measurements, and the definition of the main features of new-generation instrumentation optimized for the mechanical phenotyping of clinical specimens. In the longer-term, Phys2BioMed will provide the platform and know-how to build a data bank of mechanical fingerprints of diseases, setting the ground for the development of effective early-diagnostic tools.

Coordinador

UNIVERSITA DEGLI STUDI DI MILANO
Aportación neta de la UEn
€ 522 999,36
Dirección
Via Festa Del Perdono 7
20122 Milano
Italia

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Región
Nord-Ovest Lombardia Milano
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 522 999,36

Participantes (10)

Socios (5)