Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response

Informations projet

aDDRess

N° de convention de subvention: 812829

DOI

10.3030/812829

Projet clôturé

Date de signature de la CE 17 Août 2018

Date de début 1 Mars 2019

Date de fin 31 Decembre 2023

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 4 011 939,00

Contribution de l’UE

€ 4 011 939,00

Coordonné par

IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (28)

Podcasts & Videocasts Part I

As described in annex I

1st Annual Network Meeting

As described in annex I

2nd aDDRess Newsletter

As described in annex I

Project management course

As described in annex I

Workshop1

As described in annex I

Bioethics course

As described in annex I

4th aDDRess Newsletter

As described in annex I

International course on Laboratory Animals

As described in annex I

1st aDDRess Newsletter

As described in annex I

2nd aDDRess Summer School on Bioimaging

As described in annex I

Recruitment of ESRs

As described in annex I

Workshop 3

As described in annex I

Final Network Conference

As described in annex I

Visits & Secondments of ESRs

As described in annex I

3rd Open Lab Day

As described in annnex I

Communication, Scientific Writing & Presentation course

As described in annex I

Business & Entrepreneurship course

As described in annex I

ESRs' PhDs

The deliverable date is tentative; see annex I

Workshop 4

As described in annex I

1st Open Lab Day

As described in annex I

2nd Open Lab Day

As described in annex I

4th Open Lab Day

As described in annex I

Facebook aDDRess page

As described in annex I

3rd aDDRess Newsletter

As described in annex I

aDDRess @ Patient Clinic

As described in annex I

Workshop 2

As described in annex I

aDDRess website

As described in annex I

Podcasts & Videocasts Part II

As described in annex I

Open Research Data Pilot (1)

Open access Publications and Participation of ESRs in Conferences& Symposia

As described in annex I

Publications

Peer reviewed articles (23)

The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination

Auteurs: Altmannova, Veronika; Spirek, Mario; Orlic, Lucija; Jēkabsons, Atis; Clarence, Tereza; Henggeler, Adrian; Mlcouskova, Jarmila; Chaleil, Raphaël A.G.; Matos, Joao; Krejci, Lumir
Publié dans: eScience, Numéro 16, 2022, ISSN 2589-0042
Éditeur: [Cambridge, MA] Cell Press, Elsevier Inc.
DOI: 10.1016/j.isci.2022.105439

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks

Auteurs: Caron, Pierre; Pobega, Enrico; Polo, Sophie
Publié dans: "Frontiers in Genetics, 2021, 12, ⟨10.3389/fgene.2021.730696⟩", Numéro 16, 2021, ISSN 1664-8021
Éditeur: Frontiers Media
DOI: 10.3389/fgene.2021.730696

DNA Damage Response and Metabolic Reprogramming in Health and Disease

Auteurs: Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA.
Publié dans: Trends Genet., 2020, Page(s) Oct;36(10):777-791, ISSN 1664-8021
Éditeur: Frontiers Media
DOI: 10.1016/j.tig.2020.06.018

Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas

Auteurs: Luuk Harbers; Luuk Harbers; Federico Agostini; Federico Agostini; Marcin Nicos; Dimitri Poddighe; Dimitri Poddighe; Magda Bienko; Magda Bienko; Nicola Crosetto; Nicola Crosetto
Publié dans: Frontiers in Oncology, Vol 11 (2021), Numéro 3, 2021, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.700568

3D Genome Organization as an Epigenetic Determinant of Transcription Regulation in T Cells

Auteurs: Papadogkonas G, Papamatheakis DA, Spilianakis C.
Publié dans: Front Immunol, Numéro 2022 Jun 22;13:921375, 2022, ISSN 1664-3224
Éditeur: Frontiers Media S.A., 2010-
DOI: 10.3389/fimmu.2022.921375

Imaging the Response to DNA Damage in Heterochromatin Domains

Auteurs: Chansard A, Pobega E, Caron P, Polo SE
Publié dans: Front Cell Dev Biol, 2022, ISSN 2296-634X
Éditeur: Lausanne: Frontiers Media S.A., 2013-
DOI: 10.3389/fcell.2022.920267

DNA damage, inflammation and aging: Insights from mice

Auteurs: Ermioni S. Arvanitaki; Ermioni S. Arvanitaki; Kalliopi Stratigi; George A. Garinis; George A. Garinis
Publié dans: Frontiers in Aging, Vol 3 (2022), Numéro 16, 2022, ISSN 2673-6217
Éditeur: Lausanne, Switzerland Frontiers Media SA [2020]-
DOI: 10.3389/fragi.2022.973781

Looping forward: exploring R-loop processing and therapeutic potential

Auteurs: Stratigi K, Siametis A, Garinis GA
Publié dans: FEBS Letters, 2024, ISSN 1873-3468
Éditeur: https://febs.onlinelibrary.wiley.com/journal/18733468
DOI: 10.1002/1873-3468.14947

Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repair

Auteurs: Galina Glousker, Anna‐Sophia Briod, Manfredo Quadroni, Joachim Lingner
Publié dans: The EMBO Journal, Numéro 39:e104500, 2020, ISSN 0261-4189
Éditeur: Nature Publishing Group
DOI: 10.15252/embj.2020104500

Expression and differential regulation of human TERRA at several chromosome ends

Auteurs: Marianna Feretzaki, Patricia Renck Nunes and Joachim Lingner
Publié dans: RNA, Numéro 25, 2019, Page(s) 1470-1480, ISSN 1355-8382
Éditeur: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.072322.119

The makings of TERRA R-loops at chromosome ends

Auteurs: Rita Valador Fernandes; Marianna Feretzaki; Joachim Lingner
Publié dans: Crossref, Numéro 8, 2021, ISSN 1538-4101
Éditeur: Landes Bioscience
DOI: 10.1080/15384101.2021.1962638

RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

Auteurs: Marianna Feretzaki, Michaela Pospisilova, Rita Valador Fernandes, Thomas Lunardi, Lumir Krejci, Joachim Lingner
Publié dans: Nature, Numéro 587/7833, 2020, Page(s) 303-308, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/s41586-020-2815-6

Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

Auteurs: Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA
Publié dans: Nature Communications, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-48443-6

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

Auteurs: Maria Tsekrekou; Maria Tsekrekou; Theodore Kosteas; Kalliopi Stratigi; Eleftheria Ledaki; Georgia Chatzinikolaou; Nikos Batsiotos; Nikos Batsiotos; Mariana Ascensão-Ferreira; Janine Altmüller; Pantelis Topalis; Nuno L. Barbosa-Morais; George A. Garinis; George A. Garinis; Evi Goulielmaki; Jeroen Demmers
Publié dans: urn:issn:2041-1723, Numéro 16, 2021, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-23505-1

An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination

Auteurs: Ballarino, Roberto; Bouwman, Britta A. M.; Agostini, Federico; Harbers, Luuk; Diekmann, Constantin; Wernersson, Erik; Bienko, Magda; Crosetto, Nicola
Publié dans: Scientific Data, Vol 9, Iss 1, Pp 1-19 (2022), Numéro 10, 2022, ISSN 2052-4463
Éditeur: [London] Springer Nature
DOI: 10.1038/s41597-022-01508-x

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes

Auteurs: Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou-Clocher A, Tsamardinos I, Topalis P, Austin C, Bouwman BAM, Crosetto N, Altmüller J, Garinis GA
Publié dans: Science Advances, 2023, ISSN 2375-2548
Éditeur: Washington, DC American Association for the Advancement of Science [2015]- Country: United St
DOI: 10.1126/sciadv.adi2095

Ubiquitylation at Stressed Replication Forks: Mechanisms and Functions

Auteurs: Ann Schirin Mirsanaye, Dimitris Typas, Niels Mailand
Publié dans: Trends in Cell Biology, Numéro Feb 18;S0962-8924(21)00023-4, 2021, Page(s) 1-14, ISSN 0962-8924
Éditeur: Elsevier BV
DOI: 10.1016/j.tcb.2021.01.008

TFIIH moonlighting at telomeres

Auteurs: Glousker G, Lingner J
Publié dans: Genes Dev, 2022, ISSN 0890-9369
Éditeur: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.350140.122

The human telomeric proteome during telomere replication

Auteurs: Lin CG, Näger AC, Lunardi T, Vančevska A, Lossaint G, Lingner J
Publié dans: NAR, 2021, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkab1015

PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage

Auteurs: Wareed Ahmed and Joachim Lingne
Publié dans: Cell Reports, Numéro 33, 108347, November 3, 2020, 2020, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2020.108347

R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage

Auteurs: Chatzidoukaki O, Stratigi K, Goulielmaki E, Niotis G, Akalestou-Clocher A, Gkirtzimanaki K, Zafeiropoulos A, Altmüller J, Topalis P, Garinis GA
Publié dans: Science Advances, 2021, ISSN 2375-2548
Éditeur: Washington, DC American Association for the Advancement of Science [2015]-
DOI: 10.1126/sciadv.abj5769

DNA Damage and the Aging Epigenome

Auteurs: Siametis A, Niotis G, Garinis GA.
Publié dans: J Invest Dermatol., 2020, ISSN 0065-2253
Éditeur: 2016- : New York : Elsevier
DOI: 10.1016/j.jid.2020.10.006

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cells

Auteurs: Rita Valador Fernandes; Joachim Lingner
Publié dans: Crossref, Numéro 16, 2023, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkad448