Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response

Project Information

aDDRess

Grant agreement ID: 812829

DOI

10.3030/812829

Project closed

EC signature date 17 August 2018

Start date 1 March 2019

End date 31 December 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 4 011 939,00

EU contribution

€ 4 011 939,00

Coordinated by

IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (28)

Podcasts & Videocasts Part I

As described in annex I

1st Annual Network Meeting

As described in annex I

2nd aDDRess Newsletter

As described in annex I

Project management course

As described in annex I

Workshop1

As described in annex I

Bioethics course

As described in annex I

4th aDDRess Newsletter

As described in annex I

International course on Laboratory Animals

As described in annex I

1st aDDRess Newsletter

As described in annex I

2nd aDDRess Summer School on Bioimaging

As described in annex I

Recruitment of ESRs

As described in annex I

Workshop 3

As described in annex I

Final Network Conference

As described in annex I

Visits & Secondments of ESRs

As described in annex I

3rd Open Lab Day

As described in annnex I

Communication, Scientific Writing & Presentation course

As described in annex I

Business & Entrepreneurship course

As described in annex I

ESRs' PhDs

The deliverable date is tentative; see annex I

Workshop 4

As described in annex I

1st Open Lab Day

As described in annex I

2nd Open Lab Day

As described in annex I

4th Open Lab Day

As described in annex I

Facebook aDDRess page

As described in annex I

3rd aDDRess Newsletter

As described in annex I

aDDRess @ Patient Clinic

As described in annex I

Workshop 2

As described in annex I

aDDRess website

As described in annex I

Podcasts & Videocasts Part II

As described in annex I

Open Research Data Pilot (1)

Open access Publications and Participation of ESRs in Conferences& Symposia

As described in annex I

Publications

Peer reviewed articles (23)

The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination

Author(s): Altmannova, Veronika; Spirek, Mario; Orlic, Lucija; Jēkabsons, Atis; Clarence, Tereza; Henggeler, Adrian; Mlcouskova, Jarmila; Chaleil, Raphaël A.G.; Matos, Joao; Krejci, Lumir
Published in: eScience, Issue 16, 2022, ISSN 2589-0042
Publisher: [Cambridge, MA] Cell Press, Elsevier Inc.
DOI: 10.1016/j.isci.2022.105439

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks

Author(s): Caron, Pierre; Pobega, Enrico; Polo, Sophie
Published in: "Frontiers in Genetics, 2021, 12, ⟨10.3389/fgene.2021.730696⟩", Issue 16, 2021, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2021.730696

DNA Damage Response and Metabolic Reprogramming in Health and Disease

Author(s): Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA.
Published in: Trends Genet., 2020, Page(s) Oct;36(10):777-791, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.1016/j.tig.2020.06.018

Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas

Author(s): Luuk Harbers; Luuk Harbers; Federico Agostini; Federico Agostini; Marcin Nicos; Dimitri Poddighe; Dimitri Poddighe; Magda Bienko; Magda Bienko; Nicola Crosetto; Nicola Crosetto
Published in: Frontiers in Oncology, Vol 11 (2021), Issue 3, 2021, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.700568

3D Genome Organization as an Epigenetic Determinant of Transcription Regulation in T Cells

Author(s): Papadogkonas G, Papamatheakis DA, Spilianakis C.
Published in: Front Immunol, Issue 2022 Jun 22;13:921375, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A., 2010-
DOI: 10.3389/fimmu.2022.921375

Imaging the Response to DNA Damage in Heterochromatin Domains

Author(s): Chansard A, Pobega E, Caron P, Polo SE
Published in: Front Cell Dev Biol, 2022, ISSN 2296-634X
Publisher: Lausanne: Frontiers Media S.A., 2013-
DOI: 10.3389/fcell.2022.920267

DNA damage, inflammation and aging: Insights from mice

Author(s): Ermioni S. Arvanitaki; Ermioni S. Arvanitaki; Kalliopi Stratigi; George A. Garinis; George A. Garinis
Published in: Frontiers in Aging, Vol 3 (2022), Issue 16, 2022, ISSN 2673-6217
Publisher: Lausanne, Switzerland Frontiers Media SA [2020]-
DOI: 10.3389/fragi.2022.973781

Looping forward: exploring R-loop processing and therapeutic potential

Author(s): Stratigi K, Siametis A, Garinis GA
Published in: FEBS Letters, 2024, ISSN 1873-3468
Publisher: https://febs.onlinelibrary.wiley.com/journal/18733468
DOI: 10.1002/1873-3468.14947

Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repair

Author(s): Galina Glousker, Anna‐Sophia Briod, Manfredo Quadroni, Joachim Lingner
Published in: The EMBO Journal, Issue 39:e104500, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020104500

Expression and differential regulation of human TERRA at several chromosome ends

Author(s): Marianna Feretzaki, Patricia Renck Nunes and Joachim Lingner
Published in: RNA, Issue 25, 2019, Page(s) 1470-1480, ISSN 1355-8382
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.072322.119

The makings of TERRA R-loops at chromosome ends

Author(s): Rita Valador Fernandes; Marianna Feretzaki; Joachim Lingner
Published in: Crossref, Issue 8, 2021, ISSN 1538-4101
Publisher: Landes Bioscience
DOI: 10.1080/15384101.2021.1962638

RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

Author(s): Marianna Feretzaki, Michaela Pospisilova, Rita Valador Fernandes, Thomas Lunardi, Lumir Krejci, Joachim Lingner
Published in: Nature, Issue 587/7833, 2020, Page(s) 303-308, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-2815-6

Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

Author(s): Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-48443-6

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

Author(s): Maria Tsekrekou; Maria Tsekrekou; Theodore Kosteas; Kalliopi Stratigi; Eleftheria Ledaki; Georgia Chatzinikolaou; Nikos Batsiotos; Nikos Batsiotos; Mariana Ascensão-Ferreira; Janine Altmüller; Pantelis Topalis; Nuno L. Barbosa-Morais; George A. Garinis; George A. Garinis; Evi Goulielmaki; Jeroen Demmers
Published in: urn:issn:2041-1723, Issue 16, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23505-1

An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination

Author(s): Ballarino, Roberto; Bouwman, Britta A. M.; Agostini, Federico; Harbers, Luuk; Diekmann, Constantin; Wernersson, Erik; Bienko, Magda; Crosetto, Nicola
Published in: Scientific Data, Vol 9, Iss 1, Pp 1-19 (2022), Issue 10, 2022, ISSN 2052-4463
Publisher: [London] Springer Nature
DOI: 10.1038/s41597-022-01508-x

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes

Author(s): Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou-Clocher A, Tsamardinos I, Topalis P, Austin C, Bouwman BAM, Crosetto N, Altmüller J, Garinis GA
Published in: Science Advances, 2023, ISSN 2375-2548
Publisher: Washington, DC American Association for the Advancement of Science [2015]- Country: United St
DOI: 10.1126/sciadv.adi2095

Ubiquitylation at Stressed Replication Forks: Mechanisms and Functions

Author(s): Ann Schirin Mirsanaye, Dimitris Typas, Niels Mailand
Published in: Trends in Cell Biology, Issue Feb 18;S0962-8924(21)00023-4, 2021, Page(s) 1-14, ISSN 0962-8924
Publisher: Elsevier BV
DOI: 10.1016/j.tcb.2021.01.008

TFIIH moonlighting at telomeres

Author(s): Glousker G, Lingner J
Published in: Genes Dev, 2022, ISSN 0890-9369
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.350140.122

The human telomeric proteome during telomere replication

Author(s): Lin CG, Näger AC, Lunardi T, Vančevska A, Lossaint G, Lingner J
Published in: NAR, 2021, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab1015

PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage

Author(s): Wareed Ahmed and Joachim Lingne
Published in: Cell Reports, Issue 33, 108347, November 3, 2020, 2020, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.108347

R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage

Author(s): Chatzidoukaki O, Stratigi K, Goulielmaki E, Niotis G, Akalestou-Clocher A, Gkirtzimanaki K, Zafeiropoulos A, Altmüller J, Topalis P, Garinis GA
Published in: Science Advances, 2021, ISSN 2375-2548
Publisher: Washington, DC American Association for the Advancement of Science [2015]-
DOI: 10.1126/sciadv.abj5769

DNA Damage and the Aging Epigenome

Author(s): Siametis A, Niotis G, Garinis GA.
Published in: J Invest Dermatol., 2020, ISSN 0065-2253
Publisher: 2016- : New York : Elsevier
DOI: 10.1016/j.jid.2020.10.006

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cells

Author(s): Rita Valador Fernandes; Joachim Lingner
Published in: Crossref, Issue 16, 2023, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad448