Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response

Projektinformationen

aDDRess

ID Finanzhilfevereinbarung: 812829

DOI

10.3030/812829

Projekt abgeschlossen

EK-Unterschriftsdatum 17 August 2018

Startdatum 1 März 2019

Enddatum 31 Dezember 2023

Finanziert unter

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Gesamtkosten

€ 4 011 939,00

EU-Beitrag

€ 4 011 939,00

Koordiniert durch

IDRYMA TECHNOLOGIAS KAI EREVNAS
Greece

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Other (28)

Podcasts & Videocasts Part I

As described in annex I

1st Annual Network Meeting

As described in annex I

2nd aDDRess Newsletter

As described in annex I

Project management course

As described in annex I

Workshop1

As described in annex I

Bioethics course

As described in annex I

4th aDDRess Newsletter

As described in annex I

International course on Laboratory Animals

As described in annex I

1st aDDRess Newsletter

As described in annex I

2nd aDDRess Summer School on Bioimaging

As described in annex I

Recruitment of ESRs

As described in annex I

Workshop 3

As described in annex I

Final Network Conference

As described in annex I

Visits & Secondments of ESRs

As described in annex I

3rd Open Lab Day

As described in annnex I

Communication, Scientific Writing & Presentation course

As described in annex I

Business & Entrepreneurship course

As described in annex I

ESRs' PhDs

The deliverable date is tentative; see annex I

Workshop 4

As described in annex I

1st Open Lab Day

As described in annex I

2nd Open Lab Day

As described in annex I

4th Open Lab Day

As described in annex I

Facebook aDDRess page

As described in annex I

3rd aDDRess Newsletter

As described in annex I

aDDRess @ Patient Clinic

As described in annex I

Workshop 2

As described in annex I

aDDRess website

As described in annex I

Podcasts & Videocasts Part II

As described in annex I

Open Research Data Pilot (1)

Open access Publications and Participation of ESRs in Conferences& Symposia

As described in annex I

Veröffentlichungen

Peer reviewed articles (23)

The role of bivalent ions in the regulation of D-loop extension mediated by DMC1 during meiotic recombination

Autoren: Altmannova, Veronika; Spirek, Mario; Orlic, Lucija; Jēkabsons, Atis; Clarence, Tereza; Henggeler, Adrian; Mlcouskova, Jarmila; Chaleil, Raphaël A.G.; Matos, Joao; Krejci, Lumir
Veröffentlicht in: eScience, Ausgabe 16, 2022, ISSN 2589-0042
Herausgeber: [Cambridge, MA] Cell Press, Elsevier Inc.
DOI: 10.1016/j.isci.2022.105439

DNA Double-Strand Break Repair: All Roads Lead to HeterochROMAtin Marks

Autoren: Caron, Pierre; Pobega, Enrico; Polo, Sophie
Veröffentlicht in: "Frontiers in Genetics, 2021, 12, ⟨10.3389/fgene.2021.730696⟩", Ausgabe 16, 2021, ISSN 1664-8021
Herausgeber: Frontiers Media
DOI: 10.3389/fgene.2021.730696

DNA Damage Response and Metabolic Reprogramming in Health and Disease

Autoren: Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA.
Veröffentlicht in: Trends Genet., 2020, Seite(n) Oct;36(10):777-791, ISSN 1664-8021
Herausgeber: Frontiers Media
DOI: 10.1016/j.tig.2020.06.018

Somatic Copy Number Alterations in Human Cancers: An Analysis of Publicly Available Data From The Cancer Genome Atlas

Autoren: Luuk Harbers; Luuk Harbers; Federico Agostini; Federico Agostini; Marcin Nicos; Dimitri Poddighe; Dimitri Poddighe; Magda Bienko; Magda Bienko; Nicola Crosetto; Nicola Crosetto
Veröffentlicht in: Frontiers in Oncology, Vol 11 (2021), Ausgabe 3, 2021, ISSN 2234-943X
Herausgeber: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.700568

3D Genome Organization as an Epigenetic Determinant of Transcription Regulation in T Cells

Autoren: Papadogkonas G, Papamatheakis DA, Spilianakis C.
Veröffentlicht in: Front Immunol, Ausgabe 2022 Jun 22;13:921375, 2022, ISSN 1664-3224
Herausgeber: Frontiers Media S.A., 2010-
DOI: 10.3389/fimmu.2022.921375

Imaging the Response to DNA Damage in Heterochromatin Domains

Autoren: Chansard A, Pobega E, Caron P, Polo SE
Veröffentlicht in: Front Cell Dev Biol, 2022, ISSN 2296-634X
Herausgeber: Lausanne: Frontiers Media S.A., 2013-
DOI: 10.3389/fcell.2022.920267

DNA damage, inflammation and aging: Insights from mice

Autoren: Ermioni S. Arvanitaki; Ermioni S. Arvanitaki; Kalliopi Stratigi; George A. Garinis; George A. Garinis
Veröffentlicht in: Frontiers in Aging, Vol 3 (2022), Ausgabe 16, 2022, ISSN 2673-6217
Herausgeber: Lausanne, Switzerland Frontiers Media SA [2020]-
DOI: 10.3389/fragi.2022.973781

Looping forward: exploring R-loop processing and therapeutic potential

Autoren: Stratigi K, Siametis A, Garinis GA
Veröffentlicht in: FEBS Letters, 2024, ISSN 1873-3468
Herausgeber: https://febs.onlinelibrary.wiley.com/journal/18733468
DOI: 10.1002/1873-3468.14947

Human shelterin protein POT1 prevents severe telomere instability induced by homology‐directed DNA repair

Autoren: Galina Glousker, Anna‐Sophia Briod, Manfredo Quadroni, Joachim Lingner
Veröffentlicht in: The EMBO Journal, Ausgabe 39:e104500, 2020, ISSN 0261-4189
Herausgeber: Nature Publishing Group
DOI: 10.15252/embj.2020104500

Expression and differential regulation of human TERRA at several chromosome ends

Autoren: Marianna Feretzaki, Patricia Renck Nunes and Joachim Lingner
Veröffentlicht in: RNA, Ausgabe 25, 2019, Seite(n) 1470-1480, ISSN 1355-8382
Herausgeber: Cold Spring Harbor Laboratory Press
DOI: 10.1261/rna.072322.119

The makings of TERRA R-loops at chromosome ends

Autoren: Rita Valador Fernandes; Marianna Feretzaki; Joachim Lingner
Veröffentlicht in: Crossref, Ausgabe 8, 2021, ISSN 1538-4101
Herausgeber: Landes Bioscience
DOI: 10.1080/15384101.2021.1962638

RAD51-dependent recruitment of TERRA lncRNA to telomeres through R-loops

Autoren: Marianna Feretzaki, Michaela Pospisilova, Rita Valador Fernandes, Thomas Lunardi, Lumir Krejci, Joachim Lingner
Veröffentlicht in: Nature, Ausgabe 587/7833, 2020, Seite(n) 303-308, ISSN 0028-0836
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41586-020-2815-6

Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

Autoren: Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA
Veröffentlicht in: Nature Communications, 2024, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-024-48443-6

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

Autoren: Maria Tsekrekou; Maria Tsekrekou; Theodore Kosteas; Kalliopi Stratigi; Eleftheria Ledaki; Georgia Chatzinikolaou; Nikos Batsiotos; Nikos Batsiotos; Mariana Ascensão-Ferreira; Janine Altmüller; Pantelis Topalis; Nuno L. Barbosa-Morais; George A. Garinis; George A. Garinis; Evi Goulielmaki; Jeroen Demmers
Veröffentlicht in: urn:issn:2041-1723, Ausgabe 16, 2021, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-021-23505-1

An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination

Autoren: Ballarino, Roberto; Bouwman, Britta A. M.; Agostini, Federico; Harbers, Luuk; Diekmann, Constantin; Wernersson, Erik; Bienko, Magda; Crosetto, Nicola
Veröffentlicht in: Scientific Data, Vol 9, Iss 1, Pp 1-19 (2022), Ausgabe 10, 2022, ISSN 2052-4463
Herausgeber: [London] Springer Nature
DOI: 10.1038/s41597-022-01508-x

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes

Autoren: Chatzinikolaou G, Stratigi K, Siametis A, Goulielmaki E, Akalestou-Clocher A, Tsamardinos I, Topalis P, Austin C, Bouwman BAM, Crosetto N, Altmüller J, Garinis GA
Veröffentlicht in: Science Advances, 2023, ISSN 2375-2548
Herausgeber: Washington, DC American Association for the Advancement of Science [2015]- Country: United St
DOI: 10.1126/sciadv.adi2095

Ubiquitylation at Stressed Replication Forks: Mechanisms and Functions

Autoren: Ann Schirin Mirsanaye, Dimitris Typas, Niels Mailand
Veröffentlicht in: Trends in Cell Biology, Ausgabe Feb 18;S0962-8924(21)00023-4, 2021, Seite(n) 1-14, ISSN 0962-8924
Herausgeber: Elsevier BV
DOI: 10.1016/j.tcb.2021.01.008

TFIIH moonlighting at telomeres

Autoren: Glousker G, Lingner J
Veröffentlicht in: Genes Dev, 2022, ISSN 0890-9369
Herausgeber: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gad.350140.122

The human telomeric proteome during telomere replication

Autoren: Lin CG, Näger AC, Lunardi T, Vančevska A, Lossaint G, Lingner J
Veröffentlicht in: NAR, 2021, ISSN 0305-1048
Herausgeber: Oxford University Press
DOI: 10.1093/nar/gkab1015

PRDX1 Counteracts Catastrophic Telomeric Cleavage Events That Are Triggered by DNA Repair Activities Post Oxidative Damage

Autoren: Wareed Ahmed and Joachim Lingne
Veröffentlicht in: Cell Reports, Ausgabe 33, 108347, November 3, 2020, 2020, ISSN 2211-1247
Herausgeber: Cell Press
DOI: 10.1016/j.celrep.2020.108347

R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage

Autoren: Chatzidoukaki O, Stratigi K, Goulielmaki E, Niotis G, Akalestou-Clocher A, Gkirtzimanaki K, Zafeiropoulos A, Altmüller J, Topalis P, Garinis GA
Veröffentlicht in: Science Advances, 2021, ISSN 2375-2548
Herausgeber: Washington, DC American Association for the Advancement of Science [2015]-
DOI: 10.1126/sciadv.abj5769

DNA Damage and the Aging Epigenome

Autoren: Siametis A, Niotis G, Garinis GA.
Veröffentlicht in: J Invest Dermatol., 2020, ISSN 0065-2253
Herausgeber: 2016- : New York : Elsevier
DOI: 10.1016/j.jid.2020.10.006

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cells

Autoren: Rita Valador Fernandes; Joachim Lingner
Veröffentlicht in: Crossref, Ausgabe 16, 2023, ISSN 0305-1048
Herausgeber: Oxford University Press
DOI: 10.1093/nar/gkad448