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Continuous Downstream Processing of Bioproducts

Project description

Accelerating bioproduction via novel approaches to continuous downstream processing

Continuous processing has numerous advantages over batch processing, among which are enhanced product quality, greater efficiency, rapid scalability and reduced manufacturing costs. It is already standard in many industrial manufacturing applications and is increasingly being used in production of bioproducts. However, many challenges remain, particularly in the downstream processing stage, where multiple purification steps are still done in batches. With the support of the Marie Skłodowska-Curie Actions programme, the CODOBIO project is training a new cohort of scientists to facilitate continuous downstream processing via innovative process modelling, design and control.

Objective

Continuous biomanufacturing is one of the grand challenges of Europe’s bio-industry. It offers a significant opportunity to boost productivity, improve competitiveness and to reduce the environmental footprint. Current progress is impaired by shortage of trained engineers and scientists, who can design and control continuous biomanufacturing processes. This Innovative Training Network (ITN) will focus on addressing the critical gaps in research training to enable advances in continuous downstream processing. An expert consortium of nine industry partners, eight universities, one research organisation, a regulatory institution and a business consultancy has developed a research and training programme to address the most urgent topics in continuous downstream processing. These are: (1) process control and modelling (including economic modelling), (2) miniaturization, scale-up and scale-down of unit operations and (3) process design and development of integrated continuous downstream processes. Furthermore, regulatory framework questions, such as comparability of product quality between batch and continuous processes will be addressed. Adding the regulatory and environmental aspects to the scientific, technological and economic approach, makes our program interdisciplinary, comprehensive and unique. Specific Ph.D. topics for 15 ESRs have been outlined. The presented research and training programme will equip the ESRs with the scientific and important transferable skills, such as IPR, entrepreneurship, data management and innovation management. The consortium’s strong track record in the management of interdisciplinary research and training will ensure effective and timely training of the next generation of leaders able to design innovative continuous facilities of the future for Europe’s bio-industries, ensuring affordability and widened access. Exposure to academic, industry and regulatory sectors will provide the researchers with unparalleled career opportunities.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)

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Call for proposal

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(opens in new window) H2020-MSCA-ITN-2018

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Coordinator

ACIB GMBH
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 582 503,57
Address
KRENNGASSE 37/2
8010 Graz
Austria

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Region
Südösterreich Steiermark Graz
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 582 503,57

Participants (8)

Partners (11)

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