Project description
Accelerating bioproduction via novel approaches to continuous downstream processing
Continuous processing has numerous advantages over batch processing, among which are enhanced product quality, greater efficiency, rapid scalability and reduced manufacturing costs. It is already standard in many industrial manufacturing applications and is increasingly being used in production of bioproducts. However, many challenges remain, particularly in the downstream processing stage, where multiple purification steps are still done in batches. With the support of the Marie Skłodowska-Curie Actions programme, the CODOBIO project is training a new cohort of scientists to facilitate continuous downstream processing via innovative process modelling, design and control.
Objective
Continuous biomanufacturing is one of the grand challenges of Europe’s bio-industry. It offers a significant opportunity to boost productivity, improve competitiveness and to reduce the environmental footprint. Current progress is impaired by shortage of trained engineers and scientists, who can design and control continuous biomanufacturing processes. This Innovative Training Network (ITN) will focus on addressing the critical gaps in research training to enable advances in continuous downstream processing. An expert consortium of nine industry partners, eight universities, one research organisation, a regulatory institution and a business consultancy has developed a research and training programme to address the most urgent topics in continuous downstream processing. These are: (1) process control and modelling (including economic modelling), (2) miniaturization, scale-up and scale-down of unit operations and (3) process design and development of integrated continuous downstream processes. Furthermore, regulatory framework questions, such as comparability of product quality between batch and continuous processes will be addressed. Adding the regulatory and environmental aspects to the scientific, technological and economic approach, makes our program interdisciplinary, comprehensive and unique. Specific Ph.D. topics for 15 ESRs have been outlined. The presented research and training programme will equip the ESRs with the scientific and important transferable skills, such as IPR, entrepreneurship, data management and innovation management. The consortium’s strong track record in the management of interdisciplinary research and training will ensure effective and timely training of the next generation of leaders able to design innovative continuous facilities of the future for Europe’s bio-industries, ensuring affordability and widened access. Exposure to academic, industry and regulatory sectors will provide the researchers with unparalleled career opportunities.
Fields of science
Programme(s)
Coordinator
8010 Graz
Austria
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Participants (8)
2628 CN Delft
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Participation ended
54340 Pompey
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28725 Bremen
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22100 Lund
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8181 St Ruprecht An Der Raab
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
1049 001 Lisboa
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20133 Milano
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WC1E 6BT London
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Partners (11)
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
8093 Zurich
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
8092 Zuerich
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
2000 Maribor
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1220 Wien
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
2613 AX Delft
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1221 Wien
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
CB21 6GH Cambridge
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
6545 CM Nijmegen
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1202 Geneve
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1070 Bruxelles / Brussel
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Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
1180 Wien
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