Deliverables
Report on the comparison between batch and continuous chromatographic purification of the model bioproducts at microfluidic lab and pilot scale
Mixing in microscaleReport on the experimental results of mixing in microscale for the prediction of lab and pilot scale processes
Small scale analysisReport on analysis on very small scale
On-line estimation of product qualityReport on experimental results of online estimation of product quality
Power input and energy dissipation in miniaturized systemsReport on the determination of power input and energy dissipation in miniaturized systems.
Simulation of chromatographic behaviour for continuous DSPReport on the simulation of chromatographic behaviour for continuous downstream processing
PAT for integrated processesReport on use of PAT tools for the rapid development of the integrated processes
Integrated continuous processes: economic impact, drivers and futureReport on the economic impact and drivers of integrated continuous processes and how such technology can support future challenges in biopharmaceutical industry
HTS of integrated processesReport on the use on miniaturization for the high throughput screening of integrated processes
Expanded bed technology in continuous processesReport on the use of expanded bed technology in continuous processes including pilot scale processing
Purification of antibody in batch and continuousReport on the experimental results of purification of antibody in batch and continuous mode
Integration of continuous downstream processes IIReport on the integration of continuous downstream processes process feasibility studies and economic validation
Integration of continuous downstream processes IReport on the integration of continuous downstream processes development of integrated control strategies and automation
Microfluidic liquid-liquid extractionReport on experimental results of liquidliquid extraction of industrial enzymes in a microfluidic platform
Batch and continuous extraction at microfluidic, lab and pilot scaleReport on the comparison between batch and continuous extraction of industrial enzymes at microfluidic lab and pilot scale including economic and environmental analysis
Effect of RTD on product collectionReport on the effect of residence time distribution on startup and shutdown of product collection together with mathematical algorithm for decision making aid
Supervisory Board of the network constituted.
Recruitment procedure IVacancies for ESR recruitment advertised.
Final and press conferenceFinal and press conference.
Miniaturized HTSTraining course on miniaturized HTS.
Dissemination contentsmaterials produced published and available to stakeholders ie scientific community and general public via website
Policy feedbackPotential inputs for policy feedback
WebsiteDedicated project website launched.
Publications
Author(s):
Mariana N. São Pedro, Tiago C. Silva, Rohan Patil, Marcel Ottens
Published in:
Biotechnology and Bioengineering, 2021, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.27757
Author(s):
Alexander Armstrong, Kieran Horry, Tingting Cui, Martyn Hulley, Richard Turner, Suzanne S. Farid, Stephen Goldrick, Daniel G. Bracewell
Published in:
Journal of Chromatography A, Issue 1639, 2021, Page(s) 461914, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2021.461914
Author(s):
Malik Abdul Wahab, C. Domingues, Ana M. Azevedo, Virginia Chu, Joao Pedro Conde, M. Raquel Aires-Barros
Published in:
Separation and Purification Technology, Issue 332, 2024, ISSN 1383-5866
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.seppur.2023.125702
Author(s):
São Pedro, M.N., Klijn, M.E., Eppink, M.H. and Ottens, M
Published in:
Journal of Chemical Technology and Biotechnology, Issue 97, 2022, Page(s) 2347-2364, ISSN 0268-2575
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/jctb.6920
Author(s):
Maria del Carme Pons Royo; Jean-Luc Beulay; Eric Valery; Alois Jungbauer; Peter Satzer
Published in:
Reaction Chemistry and Engineering, Issue 7 (9), 2022, Page(s) 2045 - 2053, ISSN 2058-9883
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d2re00022a
Author(s):
Niklas Andersson, Joaquín Gomis Fons, Madelène Isaksson, Simon Tallvod, Daniel Espinoza, Linnea Sjökvist, Gusten Zandler Andersson, Bernt Nilsson
Published in:
Biotechnology and Bioengineering, 2023, Page(s) 10, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.28501
Author(s):
Amin Javidanbardan, Virginia Chu, João P. Conde, Ana M. Azevedo,
Published in:
Journal of Chromatography A, Issue 1661, 2022, Page(s) 462678, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2021.462678
Author(s):
Herlevi L.-M., Fernandez-Lahore M., Ferreira G.
Published in:
Biotechnology and Bioengineering, Issue 120, 10, 2023, Page(s) 2969 - 2976, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.28458
Author(s):
Touraj Eslami, Martin Steinberger, Christian Csizmazia, Alois Jungbauer, Nico Lingg
Published in:
Journal of Chromatography A, Issue Volume 1680, 13 September 2022, 463420, 2022, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2022.463420
Author(s):
Silva, TC, Eppink, M, Ottens, M
Published in:
Journal of Chromatography A, Issue 1681, 2022, Page(s) 463451, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2022.463451
Author(s):
Maria del Carme Pons Royo; Jean-Luc Beulay: Eric Valery; Alois Jungbauer; Peter Satzer
Published in:
Process Biochemistry, Issue 114, 2022, Page(s) 77-85, ISSN 1359-5113
Publisher:
Elsevier Applied Science
DOI:
10.1016/j.procbio.2022.01.017
Author(s):
João Medeiros Garcia Alcântara; Francesco Iannacci; Massimo Morbidelli; Mattia Sponchioni
Published in:
Journal of Biotechnology, 2023, ISSN 0168-1656
Publisher:
Elsevier BV
DOI:
10.1016/j.jbiotec.2023.10.005
Author(s):
Tiago Castanheira Silva, Michel Eppink, Marcel Ottens
Published in:
Journal of Chemical Technology & Biotechnology, 2021, ISSN 0268-2575
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/jctb.6792
Author(s):
Guo Y., Kangwa M., Ali W., Mayer-Gall T., Gutmann J.S., Zenneck C., Winter M., Jungbauer A., Fernandez Lahore H.M.
Published in:
Frontiers in Bioengineering and Biotechnology, Issue 11, art. no. 1135447, 2023, ISSN 2296-4185
Publisher:
Frontiers Media S.A
DOI:
10.3389/fbioe.2023.1135447
Author(s):
São Pedro, M. N., Santos, M.S., Eppink M.H.M., & Ottens, M
Published in:
Biotechnology Journal, Issue 18(1), 2023, Page(s) 2200332, ISSN 1860-7314
Publisher:
Wiley-VCH GmbH
DOI:
10.1002/biot.202200332
Author(s):
Maria del Carme Pons Royo; Tommaso De Santis: Daniel Komuczki; Peter Satzer: Alois Jungbauer
Published in:
Separation and Purification Technology, Issue 304, 2023, ISSN 1383-5866
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.seppur.2022.122373
Author(s):
João Medeiros Garcia Alcântara, Francesco Distante, Giuseppe Storti, Davide Moscatelli, Massimo Morbidelli, Mattia Sponchioni
Published in:
Biotechnology Advances, Issue 42, 2020, Page(s) 107582, ISSN 0734-9750
Publisher:
Elsevier BV
DOI:
10.1016/j.biotechadv.2020.107582
Author(s):
Ignacio Montes-Serrano; Peter Satzer; Alois Jungbauer; Astrid Dürauer
Published in:
Biotechnology and Bioengineering, Issue 119 (2), 2022, Page(s) 523 - 534, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.27983
Author(s):
Narges Lali; Peter Satzer; Alois Jungbauer
Published in:
Journal of Chromatography A, Issue 1683, 2022, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2022.463530
Author(s):
Narges Lali; Alois Jungbauer; Peter Satzer
Published in:
Journal of Chemical Technology and Biotechnology, Issue 97 (9), 2022, Page(s) 2386 - 2392, ISSN 0268-2575
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/jctb.6953
Author(s):
Madelène Isaksson, Joaquín Gomis-Fons, Niklas Andersson, Bernt Nilsson
Published in:
Journal of Chromatography A, Issue 1695, 2023, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2023.463942
Author(s):
Maria del Carme Pons Royo; Ignacio Montes‐Serrano; Eric Valery; Alois Jungbauer; Peter Satzer
Published in:
Journal of Chemical Technology and Biotechnology, Issue 97 (11), 2022, Page(s) 3183 - 3192, ISSN 1097-4660
Publisher:
John Wiley and Sons Ltd
DOI:
10.1002/jctb.7187
Author(s):
Ignacio Montes-Serrano: Daniel Paul Komuczki; Astrid Dürauer
Published in:
Chemical Engineering and Processing: Process Intensification, Issue 184, 2023, ISSN 0255-2701
Publisher:
Elsevier BV
DOI:
10.1016/j.cep.2023.109303
Author(s):
São Pedro, M.N., Eppink M.H.M., & Ottens, M
Published in:
Biotechnology Progress, Issue e3355, 2023, ISSN 8756-7938
Publisher:
American Chemical Society
DOI:
10.1002/btpr.3355
Author(s):
Touraj Eslami, Leo A. Jakob, Peter Satzer, Gerald Ebner, Alois Jungbauer, Nico Lingg
Published in:
Separation and Purification Technology, Issue Volume 281, 15 January 2022, 119985, 2022, ISSN 1383-5866
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.seppur.2021.119985
Author(s):
Amin Javidanbardan, Ana M. Azevedo, Virginia Chu, João P. Conde
Published in:
Micromachines, Issue 13, 2022, ISSN 2072-666X
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/mi13010006
Author(s):
Julia Scheffel, Madelène Isaksson, Joaquín Gomis-Fons , Hubert Schwarz,
Niklas Andersson, Björn Norén, Anita Solbrand, Veronique Chotteau, Sophia Hober,
Bernt Nilsson
Published in:
Journal of Chromatography A, Issue 1664, 2022, Page(s) 1-18, ISSN 0021-9673
Publisher:
Elsevier BV
DOI:
10.1016/j.chroma.2022.462806
Author(s):
Guo Y., Ali W., Schneider A., Salma A., Mayer-Gall T., Gutmann J.S., Fernandez Lahore H.M.
Published in:
Electrophoresis, Issue 43, issue 13-14, 2022, Page(s) 1387 - 1398, ISSN 0173-0835
Publisher:
John Wiley & Sons Ltd.
DOI:
10.1002/elps.202100220
Author(s):
São Pedro, M.N., Isaksson, M., Gomis-Fons, J., Eppink M.H.M., Nilsson, B. & Ottens,
M.
Published in:
Biotechnology & Bioengineering, Issue 120 (10), 2023, Page(s) 2989-3000, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.28466
Author(s):
Hubert Schwarz; Joaquín Gomis‐Fons; Madelène Isaksson; Julia Scheffel; Niklas Andersson; Andreas Andersson; Andreas Castan; Anita Solbrand; Sophia Hober; Bernt Nilsson; Veronique Chotteau
Published in:
Biotechnology and Bioengineering, Issue 3, 2022, Page(s) 1-18, ISSN 0006-3592
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1002/bit.28120
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