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BestTreat – Building a Gut Microbiome Engineering Toolbox for In-Situ Therapeutic Treatments for Non-alcoholic Fatty Liver Disease

Objective

BestTreat fosters education of ESRs in a project to uncover microbiome signatures for risk prediction and monitoring of NAFLD and to contribute to the development of therapeutic treatments based on metabolically beneficial microbial consortia. It trains 15 ESRs at world-leading academic institutions and companies, thus forming strong interdisciplinary links between industry, life and medical sciences, and end-users. BestTreat aims to train a new generation of highly qualified ESRs with entrepreneurial competencies in modern Life Sciences through state-of-the-art research projects. The projects focus on the identification and functional characterization of microbial consortia that contribute to metabolic control, and the application of this knowledge to develop novel leads for drug discovery and therapies for NAFLD. The new field on microbiome based therapeutics requires highly skilled scientists with interdisciplinary knowledge on medicine, systems biology and computer science, as well as hands-on experience with several types of tissue samples and model organisms that can optimally translate their research findings into sustainable improvements in clinical practice. BestTreat overcomes current barriers by establishing a strong, multidisciplinary and inter-sectoral training network, developing technologies tailored to solve key questions in human metabolism, microbiology and bioinformatics. The BestTreat programme will exploit recent developments in high-throughput and genome-wide screening technologies, combine these with modern molecular cell biology and systems biology approaches and ultimately translate the data into new leads for the discovery of live biotherapeutics. This specific cross-disciplinary training program will educate young scientists to the next level needed to advance this research field for the upcoming decennium. The training programme will be complemented with a complete set of transferable skills.

Coordinator

LEIBNIZ-INSTITUT FUR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE EV HANS-KNOLL-INSTITUT
Net EU contribution
€ 758 365,20
Address
Beutenberg Strasse 11A
07745 Jena
Germany
Activity type
Research Organisations
Non-EU contribution
€ 0,00

Participants (7)

ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Net EU contribution
€ 531 239,76
Address
Meibergdreef 15
1105AZ Amsterdam
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ITA-SUOMEN YLIOPISTO
Finland
Net EU contribution
€ 842 417,28
Address
Yliopistonranta 1 E
70211 Kuopio
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
AFEKTA TECHNOLOGIES LTD
Finland
Net EU contribution
€ 280 805,76
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Jynkanniementie 30
71800 Siilinjarvi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
 
CHR. HANSEN A/S
Denmark
Net EU contribution
€ 297 522,00
Address
Boege Alle 10-12
2970 Hoersholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CLINICAL-MICROBIOMICS AS
Denmark
Net EU contribution
€ 297 522,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Fruebjergvej 3
2100 Kobenhavn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Danmark Hovedstaden Byen København
 
DANMARKS TEKNISKE UNIVERSITET
Denmark
Net EU contribution
€ 595 044,00
Address
Anker Engelundsvej 1 Bygning 101 A
2800 Kgs Lyngby
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
RIJKSUNIVERSITEIT GRONINGEN
Netherlands
Net EU contribution
€ 531 239,76
Address
Broerstraat 5
9712CP Groningen
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Partners (6)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

FRIEDRICH-SCHILLER-UNIVERSITAT JENA
Germany
Net EU contribution
€ 0,00
Address
Furstengraben 1
07743 Jena
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

SHANGHAI SIXTH PEOPLE'S HOSPITAL
China
Net EU contribution
€ 0,00
Address
600 Yishan Road
200233 Shanghai
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

BRAVAD PRODUCTION APS
Denmark
Net EU contribution
€ 0,00
Address
Radmandsgade 55
2200 Kobenhavn
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Danmark Hovedstaden Byen København
 
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

GUBRA APS
Denmark
Net EU contribution
€ 0,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Agern Alle 1
2970 Horsholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Region
Danmark Hovedstaden Nordsjælland
 
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

UDATHA DASARADHI
Sweden
Net EU contribution
€ 0,00
Address
Welhavens Gate 1B
0166 Oslo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

BIOFACTION KG
Austria
Net EU contribution
€ 0,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Kundmanngasse 39/12
1030 Wien
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00