Project description
Collective action against bone pain
Bone pain may be due to various causes including arthritis, osteoporotic fractures or bone metastasis. Factors such as advanced age and obesity further exacerbate the occurrence of bone pain, necessitating new therapeutic modalities to improve the quality of life of sufferers. To address this unmet medical need, the EU-funded BonePainII project has brought together experts in the field to investigate the mechanisms underlying bone pain under different conditions including rare bone diseases. Researchers are studying the interaction between sensory neurons and a pathological bone microenvironment to identify targets for specific therapeutic interventions.
Objective
In Europe 20 - 30% of adults are affected at any one time by musculoskeletal pain such as arthritic pain, lower back pain, pain from osteoporotic fractures and bone metastasis, and also most rare bone diseases are very painful. Despite a huge negative impact on the quality of life of the patients and on society as a whole, no specific treatment is yet available. Therefore, there is a strong need to train highly skilled researchers within bone pain and thereby make the foundation for improved therapies. In this proposal we bring together 3 industrial beneficiaries, 8 academic beneficiaries, and one industrial partner all committed to train a new generation of 15 creative, entrepreneurial and innovative early stages researchers in bone pain research and transferable skills. The early stages researchers will train with some of the foremost neuroscientists and bone researchers in academia and industry across Europe. The BonePainII training network will provide the early stage researchers with expertise that will enable them to gain high level employment both in academia and industry. In a multidisciplinary, intersectoral and integrated project we will develop advanced 3D microfluidic in vitro platforms and high throughput techniques to investigate bone-neuron interactions; validate and investigate novel in vivo models of bone pain including a rare bone disease; and using cutting-edge technologies to identify key mechanisms underlying bone pain in osteoarthritis, rheumatoid arthritis, and cancer-induced bone pain.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- medical and health sciences clinical medicine rheumatology
- medical and health sciences clinical medicine orthopaedics
- social sciences economics and business business and management employment
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-ITN-2018
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1165 KOBENHAVN
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.