CORDIS
EU research results

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Modular cell factories for the production of 100 compounds from the shikimate pathway

Project information

Grant agreement ID: 814408

Status

Ongoing project

  • Start date

    1 January 2019

  • End date

    28 February 2023

Funded under:

H2020-EU.2.1.4.

  • Overall budget:

    € 7 995 343,75

  • EU contribution

    € 7 995 343,75

Coordinated by:

SILICOLIFE LDA

Portugal

Project description

English EN

Producing 100 high added value compounds from the shikimate pathway

Chemical synthesis is often difficult and usually results in undesired by-products. While nature can provide many products, their very low concentrations make extraction costly. Conversely, microbial production is a well-established process for compounds that are host-produced or have fully characterised biosynthetic pathways. However, major screenings are required for the efficient production of target compounds derived from nature in industrial applications. With this in mind, the EU-funded SHIKIFACTORY100 project aims to produce over 100 high added value compounds from the shikimate pathway, a hub in cell metabolism, by developing an optimised shikimate chassis. It will also propose and implement novel biosynthetic routes exploring enzyme promiscuity so as to recommend new pathways for the production of known and newly-designed compounds.

Coordinator

SILICOLIFE LDA

Address

Rua Do Canastreiro 15
4715 387 Braga

Portugal

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

EU Contribution

€ 1 091 125

Participants (10)

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

EU Contribution

€ 700 838,75

DANMARKS TEKNISKE UNIVERSITET

Denmark

EU Contribution

€ 988 000

EUROPEAN MOLECULAR BIOLOGY LABORATORY

Germany

EU Contribution

€ 792 650

DSM FOOD SPECIALTIES BV

Netherlands

EU Contribution

€ 885 000

THE UNIVERSITY OF MANCHESTER

United Kingdom

EU Contribution

€ 1 030 016,25

UNIVERSIDADE DO MINHO

Portugal

EU Contribution

€ 351 122,50

FACULDADE DE CIENCIAS SOCIAIS E HUMANAS DA UNIVERSIDADE NOVA DE LISBOA

Portugal

EU Contribution

€ 899 950

C-LECTA GMBH

Germany

EU Contribution

€ 400 900

GALCHIMIA SA

Spain

EU Contribution

€ 495 241,25

THE NATIONAL NON FOOD CROPS CENTRELBG

United Kingdom

EU Contribution

€ 360 500

Project information

Grant agreement ID: 814408

Status

Ongoing project

  • Start date

    1 January 2019

  • End date

    28 February 2023

Funded under:

H2020-EU.2.1.4.

  • Overall budget:

    € 7 995 343,75

  • EU contribution

    € 7 995 343,75

Coordinated by:

SILICOLIFE LDA

Portugal