Holistic solution to improve animal food production through deconstructing the biomolecular interactions between feed, gut microorganisms and animals in relation to performance parameters

Livrables

Compilation of laboratory and bioinformatics procedures implemented optimised and developed in HoloFood

Our Innovation Manager at partner CH will follow up on the original stakeholder survey D22 and include all relevant results from HoloFood as to devise a social impact report that presents an assessment of how HoloFood results will impact social parameters such food producers and consumers alike It will also include an assessment of how other food systems are likely to benefit for the HoloFood results from chicken and salmon

Conference abstract book

All abstracts from our conference will be assembled and printed in a single book that will be made freely available to the public through the project website

Training material available at TeSS-ELIXIR

Online training material to be employed in the training courses organised by HoloFood

HoloFood database

Partner EMBL will generate, maintain and run an overall database and interface where all the generated data will be stored for future use by both project partners and other stakeholders. The data base will be designed in a userfriendly fashion as to facilitate presentation of how all the different data sets from WPs-4:6 are interconnected.

Cloud data processing implementation

Partner EMBL will finish creation of a cloud based solution for all partners to process and store the generated data sets.

www.holofood.eu website

An inspiring and userfriendly website will be launched following the standard procedure for EU projects including information about the concsortium partners, aims, objectives, running news, results, and publications among other contents.

Publications

Impact of feed additives and host-related factors on bacterial metabolites, mucosal integrity and immune response in the ileum of broilers.

Auteurs: Duangnumsawang Yada, Zentek Jürgen, Vahjen Wilfried, Tarradas Joan, Goodarzi Boroojeni Farshad
Publié dans: Veterinary Research Communications, 2023, ISSN 1573-7446
Éditeur: Springer Nature
DOI: 10.1007/s11259-023-10135-9

Metabolic Effects of diet containing Blue Mussel (Mytilus edulis) and Blue Mussel-fed Salmon in a Mouse Model of Obesity

Auteurs: Atabak M. Azad, Annette Bernhard, Anne Shen, Lene Secher Myrmel, Anne-Katrine Lundebye, Laurène Alicia Lecaudey, Even Fjære, Quang Tri Ho, Harald Sveier, Karsten Kristiansen, Morten Tønsberg Limborg, Lise Madsen
Publié dans: Food Research International, 2023, ISSN 0963-9969
Éditeur: Elsevier BV
DOI: 10.1016/j.foodres.2023.112927

Novel strategies to improve chicken performance and welfare by unveiling host-microbiota interactions through hologenomics

Auteurs: Núria Tous; Sofia Marcos; Farshad Goodarzi Boroojeni; Ana Pérez de Rozas; Jürgen Zentek; Andone Estonba; Dorthe Sandvang; M. Thomas P. Gilbert; Enric Esteve-Garcia; Robert Finn; Antton Alberdi; Joan Tarradas
Publié dans: Frontiers in Physiology, Numéro 4, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.884925

Development and Functional Properties of Intestinal Mucus Layer in Poultry

Auteurs: Duangnumsawang, Yada, Jürgen Zentek, and Farshad Goodarzi Boroojeni
Publié dans: Frontiers In Immunology, 2021, ISSN 1664-3224
Éditeur: Frontiers Media SA
DOI: 10.3389/fimmu.2021.745849

Microbiome “Inception”: an Intestinal Cestode Shapes a Hierarchy of Microbial Communities Nested within the Host

Auteurs: Jaelle C. Brealey, Laurène A. Lecaudey, Miyako Kodama, Jacob A. Rasmussen, Harald Sveier, Nolwenn M. Dheilly, Michael D. Martin, Morten T. Limborg
Publié dans: mBio, 2022, ISSN 2161-2129
Éditeur: American Society for Microbiology
DOI: 10.1128/mbio.00679-22

Impact of microbial genome completeness on metagenomic functional inference

Auteurs: Raphael Eisenhofer, Iñaki Odriozola & Antton Alberdi
Publié dans: ISME Communications, Numéro 1, 2022, ISSN 2730-6151
Éditeur: Springer Nature
DOI: 10.1038/s43705-023-00221-z

Alterations in bacterial metabolites, cytokines, and mucosal integrity in the caecum of broilers caused by feed additives and host-related factors

Auteurs: Duangnumsawang Yada, Zentek Jürgen, Vahjen Wilfried, Tarradas Joan, Goodarzi Boroojeni Farshad
Publié dans: Frontiers in Physiology, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.935870

Salmon gut microbiota correlates with disease infection status: potential for monitoring health in farmed animals

Auteurs: Bozzi, D., Rasmussen, J. A., Carøe, C., Sveier, H., Nordøy, K., Gilbert, M. T. P., Limborg, M. T
Publié dans: Animal Microbiome, 2021, ISSN 2524-4671
Éditeur: BMC
DOI: 10.1186/s42523-021-00096-2

A strategic model of a host-microbe-microbe system reveals the importance of a joint host-microbe immune response to combat stress-induced gut dysbiosis

Auteurs: István Scheuring; Jacob A. Rasmussen; Davide Bozzi; Morten T. Limborg
Publié dans: Scheuring , I , Rasmussen , J A , Bozzi , D & Limborg , M T 2022 , ' A strategic model of a host-microbe-microbe system reveals the importance of a joint host-microbe immune response to combat stress-induced gut dysbiosis ' , Frontiers in Microbiology , vol. 13 , 912806 . https://doi.org/10.3389/fmicb.2022.912806, Numéro 3, 2022, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2022.912806

Disentangling host–microbiota complexity through hologenomics

Auteurs: Alberdi, Antton, Sandra B. Andersen, Morten T. Limborg, Robert R. Dunn, and M. Thomas P. Gilbert
Publié dans: Nature Review Genetics, 2021, ISSN 1471-0064
Éditeur: Nature Publishing
DOI: 10.1038/s41576-021-00421-0

Holo-Omics: Integrated Host-Microbiota Multi-omics for Basic and Applied Biological Research

Auteurs: Lasse Nyholm; Adam Koziol; Sofia Marcos; Amanda Bolt Botnen; Ostaizka Aizpurua; Shyam Gopalakrishnan; Shyam Gopalakrishnan; Morten T. Limborg; M. Thomas P. Gilbert; M. Thomas P. Gilbert; Antton Alberdi
Publié dans: iScience, 2020, ISSN 2589-0042
Éditeur: Cell Press Elsevier Inc
DOI: 10.1016/j.isci.2020.101414

Intestinal epigenotype of Atlantic salmon (Salmo salar) associates with tenacibaculosis and gut microbiota composition

Auteurs: Søren B. Hansen, Davide Bozzi, Sarah S.T. Mak, Cecilie G. Clausen, Tue K. Nielsen, Miyako Kodama, Lars H. Hansen, M. Thomas P. Gilbert, Morten T. Limborg
Publié dans: Genomics, 2023, ISSN 0888-7543
Éditeur: Academic Press
DOI: 10.1016/j.ygeno.2023.110629

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