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Protein Dynamics in Antiviral Processes

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Publications

ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly

Author(s): Christopher J. Neufeldt, Mirko Cortese, Pietro Scaturro, Berati Cerikan, Jeremy G. Wideman, Keisuke Tabata, Thaís Moraes, Olga Oleksiuk, Andreas Pichlmair & Ralf Bartenschlager
Published in: Nature Microbiology, 2019, ISSN 2058-5276
DOI: 10.1038/s41564-019-0586-3

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape

Author(s): Philipp Hubel, Christian Urban, Valter Bergant, William M. Schneider, Barbara Knauer, Alexey Stukalov, Pietro Scaturro, Angelika Mann, Linda Brunotte, Heinrich H. Hoffmann, John W. Schoggins, Martin Schwemmle, Matthias Mann, Charles M. Rice, Andreas Pichlmair
Published in: Nature Immunology, Issue 20/4, 2019, Page(s) 493-502, ISSN 1529-2908
DOI: 10.1038/s41590-019-0323-3

Chasing Intracellular Zika Virus Using Proteomics

Author(s): Pietro Scaturro, Anna Lena Kastner, Andreas Pichlmair
Published in: Viruses, Issue 11/9, 2019, Page(s) 878, ISSN 1999-4915
DOI: 10.3390/v11090878

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Author(s): Sepideh Sadegh, Julian Matschinske, David B. Blumenthal, Gihanna Galindez, Tim Kacprowski, Markus List, Reza Nasirigerdeh, Mhaned Oubounyt, Andreas Pichlmair, Tim Daniel Rose, Marisol Salgado-Albarrán, Julian Späth, Alexey Stukalov, Nina K. Wenke, Kevin Yuan, Josch K. Pauling and Jan Baumbach
Published in: Nature Communications, 2020, ISSN 2041-1723
DOI: 10.1038/s41467-020-17189-2

Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis

Author(s): Christian Urban, Hendrik Welsch, Katharina Heine, Sandra Wüst, Darya A. Haas, Christopher Dächert, Aparna Pandey, Andreas Pichlmair and Marco Binder
Published in: Viruses, 2020, ISSN 1999-4915
DOI: 10.3390/v12060635

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle

Author(s): Anna Płaszczyca, Pietro Scaturro, Christopher John Neufeldt, Mirko Cortese, Berati Cerikan, Salvatore Ferla, Andrea Brancale, Andreas Pichlmair, Ralf Bartenschlager
Published in: PLOS Pathogens, Issue 15/5, 2019, Page(s) e1007736, ISSN 1553-7366
DOI: 10.1371/journal.ppat.1007736

eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition

Author(s): Jennifer Deborah Wuerth, Matthias Habjan, Markus Kainulainen, Besim Berisha, Damien Bertheloot, Giulio Superti-Furga, Andreas Pichlmair, Friedemann Weber
Published in: mBio, 2020, ISSN 2150-7511
DOI: 10.1128/mbio.00976-20

Human NLRP1 is a sensor for double-stranded RNA

Author(s): Stefan Bauernfried, Matthias J. Scherr, Andreas Pichlmair, Karl E. Duderstadt, Veit Hornung
Published in: Science, Issue 371/6528, 2021, Page(s) eabd0811, ISSN 0036-8075
DOI: 10.1126/science.abd0811

Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing

Author(s): Jana Zecha, Chien-Yun Lee, Florian P. Bayer, Chen Meng, Vincent Grass, Johannes Zerweck, Karsten Schnatbaum, Thomas Michler, Andreas Pichlmair, Christina Ludwig, Bernhard Kuster
Published in: Molecular & Cellular Proteomics, Issue 19/9, 2020, Page(s) 1503-1522, ISSN 1535-9476
DOI: 10.1074/mcp.ra120.002164

The alternative cap-binding complex is required for antiviral defense in vivo

Author(s): Anna Gebhardt,Valter Bergant,Daniel Schnepf,Markus Moser,Arno Meiler,Dieudonnée Togbe,Claire Mackowiak,Line S. Reinert,Søren R. Paludan,Bernhard Ryffel,Alexey Stukalov,Peter Staeheli,Andreas Pichlmair
Published in: PLOS Pathogens, 2019, ISSN 1553-7366
DOI: 10.1371/journal.ppat.1008155

The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription

Author(s): Markus Fabits, Vladimir Gonçalves Magalhães, Baca Chan ,Virginie Girault, Endrit Elbasani, Elisa Rossetti, Eirikur Saeland, Martin Messerle,Andreas Pichlmair, Vanda Juranić Lisnić and Melanie M. Brinkmann
Published in: Microorganisms, 2020, ISSN 2076-2607
DOI: 10.3390/microorganisms8060790