Targeting the epigenome: towards a better understanding of disease pathogenesis and novel therapeutic strategies in Multiple Sclerosis

Project Information

Epi4MS

Grant agreement ID: 818170

DOI

10.3030/818170

EC signature date 14 February 2019

Start date 1 June 2019

End date 31 December 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 998 798,00

EU contribution

€ 1 998 798,00

Coordinated by

KAROLINSKA INSTITUTET
Sweden

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Epigenetic insights into multiple sclerosis disease progression

Author(s): Lara Kular, Maja Jagodic
Published in: Journal of Internal Medicine, 2020, ISSN 1365-2796
Publisher: Oxford : Blackwell Scientific Publications
DOI: 10.1111/joim.13045

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients

Author(s): Lara Kular, Ewoud Ewing, Maria Needhamsen, Majid Pahlevan Kakhki, Ruxandra Covacu, David Gomez-Cabrero, Lou Brundin, Maja Jagodic
Published in: Epigenetics, 2021, ISSN 1559-2308
Publisher: Philadelphia, PA : Taylor & Francis
DOI: 10.1080/15592294.2021.2020436

Comparison of EM-seq and PBAT methylome library methods for low-input DNA

Author(s): Yanan Han, Galina Yurevna Zheleznyakova, Yanara Marincevic-Zuniga, Majid Pahlevan Kakhki, Amanda Raine, Maria Needhamsen, Maja Jagodic
Published in: Epigenetics, 2021, ISSN 1559-2308
Publisher: Philadelphia, PA : Taylor & Francis
DOI: 10.1080/15592294.2021.1997406

Microglial autophagy-associated phagocytosis is essential for recovery from neuroinflammation

Author(s): Rasmus Berglund, Andre Ortlieb Guerreiro-Cacais, Milena Z Adzemovic, Manuel Zeitelhofer, Harald Lund, Ewoud Ewing, Sabrina Ruhrmann, Erik Nutma, Roham Parsa, Melanie Thessen-Hedreul, Sandra Amor, Robert A Harris, Tomas Olsson, Maja Jagodic
Published in: Science Immunology, 2020, ISSN 2470-9468
Publisher: Washington, DC : American Association for the Advancement of Science
DOI: 10.1126/sciimmunol.abb5077

Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology

Author(s): Galina Yurevna Zheleznyakova; Eliane Piket; Maria Needhamsen; Michael Hagemann-Jensen; Diana Ekman; Yanan Han; Tojo James; Mohsen Khademi; Faiez Al Nimer; Patrick Scicluna; Jesse Huang; Ingrid Kockum; Omid R. Faridani; Tomas Olsson; Fredrik Piehl; Maja Jagodic
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2021, ISSN 1091-6490
Publisher: Washington, DC : National Academy of Sciences
DOI: 10.1073/pnas.2011574118

A validated generally applicable approach using the systematic assessment of disease modules by GWAS reveals a multi-omic module strongly associated with risk factors in multiple sclerosis

Author(s): Tejaswi V S Badam, Hendrik A de Weerd, David Martínez-Enguita, Tomas Olsson, Lars Alfredsson, Ingrid Kockum, Maja Jagodic, Zelmina Lubovac-Pilav, Mika Gustafsson
Published in: BMC Genomics, 2021, ISSN 1471-2164
Publisher: BioMed Central
DOI: 10.1186/s12864-021-07935-1