Imaging Biomolecular Self-Assembly with a Molecular Photonic Scale

Información del proyecto

PHOTOMASS

Identificador del acuerdo de subvención: 819593

DOI

10.3030/819593

Proyecto cerrado

Fecha de la firma de la CE 23 Enero 2019

Fecha de inicio 1 Junio 2019

Fecha de finalización 30 Noviembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 999 574,00

Aportación de la UE

€ 1 999 574,00

Coordinado por

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (31)

Effect of temperature and nucleotide on the binding of <scp>BiP</scp> chaperone to a protein substrate

Autores: Maira Rivera; Francesca Burgos‐Bravo; Felipe Engelberger; Roi Asor; Miguel I. A. Lagos‐Espinoza; Maximiliano Figueroa; Philipp Kukura; César A. Ramírez‐Sarmiento; Mauricio Baez; Steven B. Smith; Christian A. M. Wilson
Publicado en: Protein Science, Edición 32(7), 2023, Página(s) e4706, ISSN 0961-8368
Editor: Cold Spring Harbor Laboratory Press
DOI: 10.1002/pro.4706

Single molecule mass photometry of nucleic acids

Autores: Yiwen Li, Weston B Struwe, Philipp Kukura
Publicado en: Nucleic Acids Research, Edición 48/17, 2020, Página(s) e97-e97, ISSN 0305-1048
Editor: Oxford University Press
DOI: 10.1093/nar/gkaa632

Lipids mediate supramolecular outer membrane protein assembly in bacteria

Autores: Melissa N. Webby; Abraham O. Oluwole; Conrado Pedebos; Patrick G. Inns; Anna Olerinyova; Dheeraj Prakaash; Nicholas G. Housden; Georgina Benn; Dawei Sun; Bart W. Hoogenboom; Philipp Kukura; Shabaz Mohammed; Carol V. Robinson; Syma Khalid; Colin Kleanthous
Publicado en: Crossref, Edición 3, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adc9566

Direct observation of the molecular mechanism underlying protein polymerization

Autores: Hundt, Nikolas; Cole, Daniel; Hantke, Max F; Miller, Jack J; Struwe, Weston B; Kukura, Philipp
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abm7935

Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes

Autores: Seraphim TV, Nano N, Cheung YWS, Aluksanasuwan S, Colleti C, Mao Y-Q, Bhandari V, Young G, Höll L, Phanse S, Gordiyenko Y, Southworth DR, Robinson CV, Thongboonkerd V, Gava LM, Borges JC, Babu M, Barbosa LRS, Ramos CHI, Kukura P, Houry WA
Publicado en: Structure, Edición 30, 2021, Página(s) 1-16, ISSN 1878-4186
Editor: CellPress
DOI: 10.1016/j.str.2021.08.002

Characterization of membrane protein interactions by peptidisc-mediated mass photometry

Autores: John William Young, Emanuel Pfitzner, Raman van Wee, Carla Kirschbaum, Philipp Kukura, Carol V. Robinson
Publicado en: IScience, 2024, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2024.108785

Long-range ballistic propagation of carriers in methylammonium lead iodide perovskite thin films

Autores: Sung J, Schnedermann C, Ni L, Sadhanala A, Chen RYS, Cho C, Priest L, Lim JM, Kim HK, Monserrat B, Kukura P, Rao A
Publicado en: Nature Physics, Edición 16, 2019, Página(s) 171-176, ISSN 1745-2473
Editor: Nature Publishing Group
DOI: 10.1038/s41567-019-0730-2

Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track

Autores: Adam Fineberg; Yasuharu Takagi; Kavitha Thirumurugan; Joanna Andrecka; Neil Billington; Gavin Young; Daniel Cole; Stan A. Burgess; Alistair P. Curd; John A. Hammer; James R. Sellers; Philipp Kukura; Peter J. Knight
Publicado en: PNAS, Edición 121 (13), 2024, Página(s) e2401625121, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2401625121

Micromirror total internal reflection microscopy for high-performance single particle tracking at interfaces

Autores: Meng, Xuanhui; Sonn-Segev, Adar; Schumacher, Anne; Cole, Daniel; Young, Gavin; Thorpe, Stephen; Style, Robert W.; Dufresne, Eric R.; Kukura, Philipp
Publicado en: ACSPhotonics, Edición 8 10, 2021, Página(s) 3111-3118, ISSN 2330-4022
Editor: American Chemical Society
DOI: 10.1021/acsphotonics.1c01268

Quantifying Protein–Protein Interactions by Molecular Counting with Mass Photometry

Autores: Fabian Soltermann, Eric D. B. Foley, Veronica Pagnoni, Martin Galpin, Justin L. P. Benesch, Philipp Kukura, Weston B. Struwe
Publicado en: Angewandte Chemie International Edition, Edición 59/27, 2020, Página(s) 10774-10779, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202001578

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation

Autores: Markus Meier; Monika Gupta; Serife Akgül; Matthew McDougall; Thomas Imhof; Denise Nikodemus; Raphael Reuten; Aniel Moya-Torres; Vu To; Fraser Ferens; Fabian Heide; Gay Pauline Padilla-Meier; Philipp Kukura; Wenming Huang; Birgit Gerisch; Matthias Mörgelin; Kate Poole; Adam Antebi; Manuel Koch; Jörg Stetefeld
Publicado en: Nature Communications, Edición 1, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-36692-w

Coupled Metabolic Cycles Allow Out‐of‐Equilibrium Autopoietic Vesicle Replication

Autores: Anthonius H. J. Engwerda; Josh Southworth; Maria A. Lebedeva; Robert J. H. Scanes; Philipp Kukura; Stephen P. Fletcher
Publicado en: Angewandte Chemie (International Ed. in English), Edición 2, 2020, ISSN 1521-3773
Editor: Wiley
DOI: 10.1002/anie.202007302

Characterising biomolecular interactions and dynamics with mass photometry

Autores: Asor, R; Kukura, P
Publicado en: Crossref, Edición 2, 2022, Página(s) 102132, ISSN 1367-5931
Editor: Elsevier BV
DOI: 10.1016/j.cbpa.2022.102132

Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning

Autores: Jiří Kratochvíl, Roi Asor, Seham Helmi, Weston B. Struwe, Philipp Kukura
Publicado en: Nano Letters, Edición 24, 2024, Página(s) 10032-10039, ISSN 1530-6984
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.4c01667

Myosin II filament dynamics in action networks revealed with interferometric scattering microscopy

Autores: Mosby LS, Hundt N, Young G, Fineberg A, Polin M, Mayor S, Kukura P, Koester DV
Publicado en: Biophysical Journal, Edición 118 (8), 2020, Página(s) 1946-1957, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2020.02.025

A quantitative description for optical mass measurement of single biomolecules

Autores: Jan Becker; Jack S. Peters; Ivor Crooks; Seham Helmi; Marie Synakewicz; Benjamin Schuler; Philipp Kukura
Publicado en: ACS Photonics, Edición 10 (8), 2023, Página(s) 2699-2710, ISSN 2330-4022
Editor: American Chemical Society
DOI: 10.1021/acsphotonics.3c00422

Enhanced Interferometric Imaging by Rotating Coherent Scattering Microscopy

Autores: Kishwar Iqbal, Jan Christoph Thiele, Emanuel Pfitzner, Philipp Kukura
Publicado en: ACS Photonics, 2025, ISSN 2330-4022
Editor: American Chemical Society
DOI: 10.1021/acsphotonics.5c00123

Mass Photometry of Membrane Proteins

Autores: Anna Olerinyova; Adar Sonn-Segev; Joseph Gault; Cédric Eichmann; Johannes Schimpf; Adrian H. Kopf; Lucas S.P. Rudden; Dzmitry Ashkinadze; Radoslaw Bomba; Jason Greenwald; Matteo T. Degiacomi; J. Antoinette Killian; Thorsten Friedrich; Roland Riek; Weston B. Struwe; Philipp Kukura
Publicado en: Chem, Edición Volume 7, issue 1, 2020, Página(s) 224-236, ISSN 1097-4172
Editor: CellPress
DOI: 10.1101/2020.02.28.969287

Single molecule mass photometry reveals the dynamic oligomerization of human and plant peroxiredoxins

Autores: Michael Liebthal, Manish Singh Kushwah, Philipp Kukura, Karl-Josef Dietz
Publicado en: iScience, Edición 19.11.2021, 2021, Página(s) 103258, ISSN 2589-0042
Editor: Cell Press
DOI: 10.1016/j.isci.2021.103258

Roadmap on Label-Free Super-Resolution Imaging

Autores: Vasily N. Astratov,* Yair Ben Sahel, Yonina C. Eldar, Luzhe Huang, Aydogan Ozcan,Nikolay Zheludev, Junxiang Zhao, Zachary Burns, Zhaowei Liu, Evgenii Narimanov,Neha Goswami, Gabriel Popescu, Emanuel Pfitzner, Philipp Kukura, Yi-Teng Hsiao,Chia-Lung Hsieh, Brian Abbey, Alberto Diaspro, Aymeric LeGratiet, Paolo Bianchini,Natan T. Shaked, Bertrand Simon, Nicolas Verrier, Matthieu Debailleul, Olivier
Publicado en: Laser & Photonics Review, Edición Volume 17, Edición 12, 2023, ISSN 1863-8880
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/lpor.202200029

Single-protein optical holography

Autores: Jan Christoph Thiele, Emanuel Pfitzner, Philipp Kukura
Publicado en: Nature Photonics, Edición 18, 2024, Página(s) 388-395, ISSN 1749-4885
Editor: Nature Pub. Group
DOI: 10.1038/s41566-024-01405-2

Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy.

Autores: Maria A. Lebedeva; Elena Palmieri; Philipp Kukura; Stephen P. Fletcher
Publicado en: ACS Nanao, Edición 5, 2020, Página(s) 11160-11168, ISSN 1936-086X
Editor: ACSPublications
DOI: 10.1021/acsnano.0c02414

Ultrafast Tracking of Exciton and Charge Carrier Transport in Optoelectronic Materials on the Nanometer Scale

Autores: Schnedermann C, Sung J, Pandya R, Verma SD, Chen RYS, Gauriot N, Bretscher H, Kukura P, Rao A
Publicado en: Journal of Physical Chemistry Letters, Edición 10 21, 2019, Página(s) 7627-6733, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.1021/acs.jpclett.9b02437

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

Autores: Alan Rodriguez Carvajal, Irina Grishkovskaya, Carlos Gomez Diaz, Antonia Vogel, Adar Sonn-Segev, Manish S Kushwah, Katrin Schodl, Luiza Deszcz, Zsuzsanna Orban-Nemeth, Shinji Sakamoto, Karl Mechtler, Philipp Kukura, Tim Clausen, David Haselbach, Fumiyo Ikeda
Publicado en: eLife, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.60660

McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation

Autores: Bence Hajdusits, Marcin J Suskiewicz, Nikolas Hundt, Anton Meinhart, Robert Kurzbauer, Julia Leodolter, Philipp Kukura, Tim Clausen
Publicado en: eLife, Edición 10, 2021, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.63505

Sensing force and charge at the nanoscale with a single-molecule tether

Autores: Xuanhui Meng, Philipp Kukura, Sanli Faez
Publicado en: Nanoscale, Edición 13/29, 2021, Página(s) 12687-12696, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/d1nr01970h

Mass photometry enables label-free tracking and mass measurement of single proteins on lipid bilayers

Autores: Foley EDB, Kushwah MS, Young G, Kukura P
Publicado en: Nature methods, Edición 18, 2021, Página(s) 1247-1252, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-021-01261-w

Quantifying the Monomer–Dimer Equilibrium of Tubulin with Mass Photometry

Autores: Adam Fineberg; Thomas Surrey; Philipp Kukura
Publicado en: Journal of Molecular Biology, Edición 432 23, 2020, Página(s) 6168-6172, ISSN 0022-2836
Editor: Academic Press
DOI: 10.1016/j.jmb.2020.10.013

Label-free methods for optical in vitro characterization of protein–protein interactions

Autores: Fabian Soltermann, Weston B. Struwe, Philipp Kukura
Publicado en: Physical Chemistry Chemical Physics, Edición 23/31, 2021, Página(s) 16488-16500, ISSN 1463-9076
Editor: Royal Society of Chemistry
DOI: 10.1039/d1cp01072g

Oligomerization-driven avidity correlates with SARS-CoV-2 cellular binding and inhibition

Autores: Roi Asor, Anna Olerinyova, Sean A Burnap, Manish S Kushwah, Fabian Soltermann, Lucas S P Rudden, Mario Hensen, Snežana Vasiljevic, Juliane Brun, Michelle Hill, Liu Chang, Wanwisa Dejnirattisai, Piyada Supasa, Juthathip Mongkolsapaya, Daming Zhou, David I Stuart, Gavin R Screaton, Matteo T Degiacomi, Nicole Zitzmann, Justin L P Benesch, Weston B Struwe, Philipp Kukura
Publicado en: Proceedings of the National Academy of Sciences, Edición 121, 2024, ISSN 1091-6490
Editor: PNAS
DOI: 10.1073/pnas.2403260121

Scattering-based Light Microscopy: From Metal Nanoparticles to Single Proteins

Autores: Lee Priest, Jack S. Peters, Philipp Kukura
Publicado en: Chemical Reviews, Edición 121/19, 2021, Página(s) 11937-11970, ISSN 0009-2665
Editor: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00271