Imaging Biomolecular Self-Assembly with a Molecular Photonic Scale

Informacje na temat projektu

PHOTOMASS

Identyfikator umowy o grant: 819593

DOI

10.3030/819593

Projekt został zamknięty

Data podpisania przez KE 23 Stycznia 2019

Data rozpoczęcia 1 Czerwca 2019

Data zakończenia 30 Listopada 2024

Finansowanie w ramach

• EXCELLENT SCIENCE - European Research Council (ERC)

Koszt całkowity

€ 1 999 574,00

Wkład UE

€ 1 999 574,00

Koordynowany przez

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Publikacje

Peer reviewed articles (31)

Effect of temperature and nucleotide on the binding of <scp>BiP</scp> chaperone to a protein substrate

Autorzy: Maira Rivera; Francesca Burgos‐Bravo; Felipe Engelberger; Roi Asor; Miguel I. A. Lagos‐Espinoza; Maximiliano Figueroa; Philipp Kukura; César A. Ramírez‐Sarmiento; Mauricio Baez; Steven B. Smith; Christian A. M. Wilson
Opublikowane w: Protein Science, Numer 32(7), 2023, Strona(/y) e4706, ISSN 0961-8368
Wydawca: Cold Spring Harbor Laboratory Press
DOI: 10.1002/pro.4706

Single molecule mass photometry of nucleic acids

Autorzy: Yiwen Li, Weston B Struwe, Philipp Kukura
Opublikowane w: Nucleic Acids Research, Numer 48/17, 2020, Strona(/y) e97-e97, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkaa632

Lipids mediate supramolecular outer membrane protein assembly in bacteria

Autorzy: Melissa N. Webby; Abraham O. Oluwole; Conrado Pedebos; Patrick G. Inns; Anna Olerinyova; Dheeraj Prakaash; Nicholas G. Housden; Georgina Benn; Dawei Sun; Bart W. Hoogenboom; Philipp Kukura; Shabaz Mohammed; Carol V. Robinson; Syma Khalid; Colin Kleanthous
Opublikowane w: Crossref, Numer 3, 2022, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adc9566

Direct observation of the molecular mechanism underlying protein polymerization

Autorzy: Hundt, Nikolas; Cole, Daniel; Hantke, Max F; Miller, Jack J; Struwe, Weston B; Kukura, Philipp
Opublikowane w: Science Advances, 2022, ISSN 2375-2548
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abm7935

Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes

Autorzy: Seraphim TV, Nano N, Cheung YWS, Aluksanasuwan S, Colleti C, Mao Y-Q, Bhandari V, Young G, Höll L, Phanse S, Gordiyenko Y, Southworth DR, Robinson CV, Thongboonkerd V, Gava LM, Borges JC, Babu M, Barbosa LRS, Ramos CHI, Kukura P, Houry WA
Opublikowane w: Structure, Numer 30, 2021, Strona(/y) 1-16, ISSN 1878-4186
Wydawca: CellPress
DOI: 10.1016/j.str.2021.08.002

Characterization of membrane protein interactions by peptidisc-mediated mass photometry

Autorzy: John William Young, Emanuel Pfitzner, Raman van Wee, Carla Kirschbaum, Philipp Kukura, Carol V. Robinson
Opublikowane w: IScience, 2024, ISSN 2589-0042
Wydawca: Cell Press
DOI: 10.1016/j.isci.2024.108785

Long-range ballistic propagation of carriers in methylammonium lead iodide perovskite thin films

Autorzy: Sung J, Schnedermann C, Ni L, Sadhanala A, Chen RYS, Cho C, Priest L, Lim JM, Kim HK, Monserrat B, Kukura P, Rao A
Opublikowane w: Nature Physics, Numer 16, 2019, Strona(/y) 171-176, ISSN 1745-2473
Wydawca: Nature Publishing Group
DOI: 10.1038/s41567-019-0730-2

Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track

Autorzy: Adam Fineberg; Yasuharu Takagi; Kavitha Thirumurugan; Joanna Andrecka; Neil Billington; Gavin Young; Daniel Cole; Stan A. Burgess; Alistair P. Curd; John A. Hammer; James R. Sellers; Philipp Kukura; Peter J. Knight
Opublikowane w: PNAS, Numer 121 (13), 2024, Strona(/y) e2401625121, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2401625121

Micromirror total internal reflection microscopy for high-performance single particle tracking at interfaces

Autorzy: Meng, Xuanhui; Sonn-Segev, Adar; Schumacher, Anne; Cole, Daniel; Young, Gavin; Thorpe, Stephen; Style, Robert W.; Dufresne, Eric R.; Kukura, Philipp
Opublikowane w: ACSPhotonics, Numer 8 10, 2021, Strona(/y) 3111-3118, ISSN 2330-4022
Wydawca: American Chemical Society
DOI: 10.1021/acsphotonics.1c01268

Quantifying Protein–Protein Interactions by Molecular Counting with Mass Photometry

Autorzy: Fabian Soltermann, Eric D. B. Foley, Veronica Pagnoni, Martin Galpin, Justin L. P. Benesch, Philipp Kukura, Weston B. Struwe
Opublikowane w: Angewandte Chemie International Edition, Numer 59/27, 2020, Strona(/y) 10774-10779, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202001578

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation

Autorzy: Markus Meier; Monika Gupta; Serife Akgül; Matthew McDougall; Thomas Imhof; Denise Nikodemus; Raphael Reuten; Aniel Moya-Torres; Vu To; Fraser Ferens; Fabian Heide; Gay Pauline Padilla-Meier; Philipp Kukura; Wenming Huang; Birgit Gerisch; Matthias Mörgelin; Kate Poole; Adam Antebi; Manuel Koch; Jörg Stetefeld
Opublikowane w: Nature Communications, Numer 1, 2023, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-36692-w

Coupled Metabolic Cycles Allow Out‐of‐Equilibrium Autopoietic Vesicle Replication

Autorzy: Anthonius H. J. Engwerda; Josh Southworth; Maria A. Lebedeva; Robert J. H. Scanes; Philipp Kukura; Stephen P. Fletcher
Opublikowane w: Angewandte Chemie (International Ed. in English), Numer 2, 2020, ISSN 1521-3773
Wydawca: Wiley
DOI: 10.1002/anie.202007302

Characterising biomolecular interactions and dynamics with mass photometry

Autorzy: Asor, R; Kukura, P
Opublikowane w: Crossref, Numer 2, 2022, Strona(/y) 102132, ISSN 1367-5931
Wydawca: Elsevier BV
DOI: 10.1016/j.cbpa.2022.102132

Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning

Autorzy: Jiří Kratochvíl, Roi Asor, Seham Helmi, Weston B. Struwe, Philipp Kukura
Opublikowane w: Nano Letters, Numer 24, 2024, Strona(/y) 10032-10039, ISSN 1530-6984
Wydawca: American Chemical Society
DOI: 10.1021/acs.nanolett.4c01667

Myosin II filament dynamics in action networks revealed with interferometric scattering microscopy

Autorzy: Mosby LS, Hundt N, Young G, Fineberg A, Polin M, Mayor S, Kukura P, Koester DV
Opublikowane w: Biophysical Journal, Numer 118 (8), 2020, Strona(/y) 1946-1957, ISSN 0006-3495
Wydawca: Biophysical Society
DOI: 10.1016/j.bpj.2020.02.025

A quantitative description for optical mass measurement of single biomolecules

Autorzy: Jan Becker; Jack S. Peters; Ivor Crooks; Seham Helmi; Marie Synakewicz; Benjamin Schuler; Philipp Kukura
Opublikowane w: ACS Photonics, Numer 10 (8), 2023, Strona(/y) 2699-2710, ISSN 2330-4022
Wydawca: American Chemical Society
DOI: 10.1021/acsphotonics.3c00422

Enhanced Interferometric Imaging by Rotating Coherent Scattering Microscopy

Autorzy: Kishwar Iqbal, Jan Christoph Thiele, Emanuel Pfitzner, Philipp Kukura
Opublikowane w: ACS Photonics, 2025, ISSN 2330-4022
Wydawca: American Chemical Society
DOI: 10.1021/acsphotonics.5c00123

Mass Photometry of Membrane Proteins

Autorzy: Anna Olerinyova; Adar Sonn-Segev; Joseph Gault; Cédric Eichmann; Johannes Schimpf; Adrian H. Kopf; Lucas S.P. Rudden; Dzmitry Ashkinadze; Radoslaw Bomba; Jason Greenwald; Matteo T. Degiacomi; J. Antoinette Killian; Thorsten Friedrich; Roland Riek; Weston B. Struwe; Philipp Kukura
Opublikowane w: Chem, Numer Volume 7, issue 1, 2020, Strona(/y) 224-236, ISSN 1097-4172
Wydawca: CellPress
DOI: 10.1101/2020.02.28.969287

Single molecule mass photometry reveals the dynamic oligomerization of human and plant peroxiredoxins

Autorzy: Michael Liebthal, Manish Singh Kushwah, Philipp Kukura, Karl-Josef Dietz
Opublikowane w: iScience, Numer 19.11.2021, 2021, Strona(/y) 103258, ISSN 2589-0042
Wydawca: Cell Press
DOI: 10.1016/j.isci.2021.103258

Roadmap on Label-Free Super-Resolution Imaging

Autorzy: Vasily N. Astratov,* Yair Ben Sahel, Yonina C. Eldar, Luzhe Huang, Aydogan Ozcan,Nikolay Zheludev, Junxiang Zhao, Zachary Burns, Zhaowei Liu, Evgenii Narimanov,Neha Goswami, Gabriel Popescu, Emanuel Pfitzner, Philipp Kukura, Yi-Teng Hsiao,Chia-Lung Hsieh, Brian Abbey, Alberto Diaspro, Aymeric LeGratiet, Paolo Bianchini,Natan T. Shaked, Bertrand Simon, Nicolas Verrier, Matthieu Debailleul, Olivier
Opublikowane w: Laser & Photonics Review, Numer Volume 17, Numer 12, 2023, ISSN 1863-8880
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/lpor.202200029

Single-protein optical holography

Autorzy: Jan Christoph Thiele, Emanuel Pfitzner, Philipp Kukura
Opublikowane w: Nature Photonics, Numer 18, 2024, Strona(/y) 388-395, ISSN 1749-4885
Wydawca: Nature Pub. Group
DOI: 10.1038/s41566-024-01405-2

Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy.

Autorzy: Maria A. Lebedeva; Elena Palmieri; Philipp Kukura; Stephen P. Fletcher
Opublikowane w: ACS Nanao, Numer 5, 2020, Strona(/y) 11160-11168, ISSN 1936-086X
Wydawca: ACSPublications
DOI: 10.1021/acsnano.0c02414

Ultrafast Tracking of Exciton and Charge Carrier Transport in Optoelectronic Materials on the Nanometer Scale

Autorzy: Schnedermann C, Sung J, Pandya R, Verma SD, Chen RYS, Gauriot N, Bretscher H, Kukura P, Rao A
Opublikowane w: Journal of Physical Chemistry Letters, Numer 10 21, 2019, Strona(/y) 7627-6733, ISSN 1948-7185
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpclett.9b02437

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

Autorzy: Alan Rodriguez Carvajal, Irina Grishkovskaya, Carlos Gomez Diaz, Antonia Vogel, Adar Sonn-Segev, Manish S Kushwah, Katrin Schodl, Luiza Deszcz, Zsuzsanna Orban-Nemeth, Shinji Sakamoto, Karl Mechtler, Philipp Kukura, Tim Clausen, David Haselbach, Fumiyo Ikeda
Opublikowane w: eLife, 2021, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.60660

McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation

Autorzy: Bence Hajdusits, Marcin J Suskiewicz, Nikolas Hundt, Anton Meinhart, Robert Kurzbauer, Julia Leodolter, Philipp Kukura, Tim Clausen
Opublikowane w: eLife, Numer 10, 2021, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.63505

Sensing force and charge at the nanoscale with a single-molecule tether

Autorzy: Xuanhui Meng, Philipp Kukura, Sanli Faez
Opublikowane w: Nanoscale, Numer 13/29, 2021, Strona(/y) 12687-12696, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1nr01970h

Mass photometry enables label-free tracking and mass measurement of single proteins on lipid bilayers

Autorzy: Foley EDB, Kushwah MS, Young G, Kukura P
Opublikowane w: Nature methods, Numer 18, 2021, Strona(/y) 1247-1252, ISSN 1548-7091
Wydawca: Nature Publishing Group
DOI: 10.1038/s41592-021-01261-w

Quantifying the Monomer–Dimer Equilibrium of Tubulin with Mass Photometry

Autorzy: Adam Fineberg; Thomas Surrey; Philipp Kukura
Opublikowane w: Journal of Molecular Biology, Numer 432 23, 2020, Strona(/y) 6168-6172, ISSN 0022-2836
Wydawca: Academic Press
DOI: 10.1016/j.jmb.2020.10.013

Label-free methods for optical in vitro characterization of protein–protein interactions

Autorzy: Fabian Soltermann, Weston B. Struwe, Philipp Kukura
Opublikowane w: Physical Chemistry Chemical Physics, Numer 23/31, 2021, Strona(/y) 16488-16500, ISSN 1463-9076
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d1cp01072g

Oligomerization-driven avidity correlates with SARS-CoV-2 cellular binding and inhibition

Autorzy: Roi Asor, Anna Olerinyova, Sean A Burnap, Manish S Kushwah, Fabian Soltermann, Lucas S P Rudden, Mario Hensen, Snežana Vasiljevic, Juliane Brun, Michelle Hill, Liu Chang, Wanwisa Dejnirattisai, Piyada Supasa, Juthathip Mongkolsapaya, Daming Zhou, David I Stuart, Gavin R Screaton, Matteo T Degiacomi, Nicole Zitzmann, Justin L P Benesch, Weston B Struwe, Philipp Kukura
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 121, 2024, ISSN 1091-6490
Wydawca: PNAS
DOI: 10.1073/pnas.2403260121

Scattering-based Light Microscopy: From Metal Nanoparticles to Single Proteins

Autorzy: Lee Priest, Jack S. Peters, Philipp Kukura
Opublikowane w: Chemical Reviews, Numer 121/19, 2021, Strona(/y) 11937-11970, ISSN 0009-2665
Wydawca: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00271