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Self-organization of the cilium: the role of the tubulin code

Publications

The structural basis of intraflagellar transport at a glance

Author(s): Mareike A. Jordan, Gaia Pigino
Published in: Journal of Cell Science, 00219533, 2021, Page(s) jcs247163, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.247163

In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains.

Author(s): van den Hoek H, Klena N, Jordan MA, Alvarez Viar Gonzalo, Righetto RD, Schaffer M, Erdmann PS, Wan W, Geimer S, Plitzko JM, Baumeister W, Pigino Gaia, Hamel V, Guichard P, Engel BD.
Published in: Science, 00368075, 2022, Page(s) 543-548, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abm6704

Towards a mechanistic understanding of cellular processes by cryoEM

Author(s): Adrian Pascal Nievergelt, Gonzalo Alvarez Viar, Gaia Pigino
Published in: Current Opinion in Structural Biology, 58, 2019, Page(s) 149-158, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2019.06.008

The molecular structure of mammalian primary cilia revealed by cryo-electron tomography

Author(s): Petra Kiesel, Gonzalo Alvarez Viar, Nikolai Tsoy, Riccardo Maraspini, Peter Gorilak, Vladimir Varga, Alf Honigmann, Gaia Pigino
Published in: Nature Structural & Molecular Biology, 2020, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-020-0507-4

Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility

Author(s): Sudarshan Gadadhar, Gonzalo Alvarez Viar, Jan Niklas Hansen, An Gong, Aleksandr Kostarev, Côme Ialy-Radio, Sophie Leboucher, Marjorie Whitfield, Ahmed Ziyyat, Aminata Touré, Luis Alvarez, Gaia Pigino, Carsten Janke
Published in: Science, 371/6525, 2021, Page(s) all, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abd4914

In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip

Author(s): Jenna L. Wingfield, Betlehem Mekonnen, Ilaria Mengoni, Peiwei Liu,Mareike Jordan, Dennis Diener, Gaia Pigino , Karl Lechtreck
Published in: Journal of Cell Science, 00219533, 2021, Page(s) jcs259010, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.259010

Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport.

Author(s): Nievergelt Adrian, Zykov Ilia, Diener Diener, Chhatre Aditya, Buchholz TimOliver, Delling Markus, Diez Stefan, Jug Florian, Štěpánek Ludek, Pigino Gaia.
Published in: Current Biology, 09609822, 2022, Page(s) 4071-4078, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2022.07.033

Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link

Author(s): Rafał Bazan, Adam Schröfel, Ewa Joachimiak, Martyna Poprzeczko, Gaia Pigino, Dorota Wloga
Published in: PLOS Genetics, 17/3, 2021, Page(s) e1009388, ISSN 1553-7404
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1009388