Self-organization of the cilium: the role of the tubulin code

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The structural basis of intraflagellar transport at a glance

Autores: Mareike A. Jordan, Gaia Pigino
Publicado en: Journal of Cell Science, Edición 00219533, 2021, Página(s) jcs247163, ISSN 0021-9533
Editor: The Company of Biologists Ltd.
DOI: 10.1242/jcs.247163

In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains.

Autores: van den Hoek H, Klena N, Jordan MA, Alvarez Viar Gonzalo, Righetto RD, Schaffer M, Erdmann PS, Wan W, Geimer S, Plitzko JM, Baumeister W, Pigino Gaia, Hamel V, Guichard P, Engel BD.
Publicado en: Science, Edición 00368075, 2022, Página(s) 543-548, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.abm6704

Towards a mechanistic understanding of cellular processes by cryoEM

Autores: Adrian Pascal Nievergelt, Gonzalo Alvarez Viar, Gaia Pigino
Publicado en: Current Opinion in Structural Biology, Edición 58, 2019, Página(s) 149-158, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2019.06.008

The molecular structure of mammalian primary cilia revealed by cryo-electron tomography

Autores: Petra Kiesel, Gonzalo Alvarez Viar, Nikolai Tsoy, Riccardo Maraspini, Peter Gorilak, Vladimir Varga, Alf Honigmann, Gaia Pigino
Publicado en: Nature Structural & Molecular Biology, 2020, ISSN 1545-9993
Editor: Nature Publishing Group
DOI: 10.1038/s41594-020-0507-4

The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains

Autores: Samuel E Lacey, Helen E Foster, Gaia Pigino
Publicado en: Nature Structural Molecular Biology, 2023, ISSN 1545-9993
Editor: Nature Publishing Group
DOI: 10.1038/s41594-022-00905-5

Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility

Autores: Sudarshan Gadadhar, Gonzalo Alvarez Viar, Jan Niklas Hansen, An Gong, Aleksandr Kostarev, Côme Ialy-Radio, Sophie Leboucher, Marjorie Whitfield, Ahmed Ziyyat, Aminata Touré, Luis Alvarez, Gaia Pigino, Carsten Janke
Publicado en: Science, Edición 371/6525, 2021, Página(s) all, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.abd4914

Structural Biology of Cilia and Intraflagellar Transport

Autores: Nikolai Klena, Gaia Pigino
Publicado en: Annual Review of Cell and Developmental Biology, 2022, ISSN 1081-0706
Editor: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-120219-034238

In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip

Autores: Jenna L. Wingfield, Betlehem Mekonnen, Ilaria Mengoni, Peiwei Liu,Mareike Jordan, Dennis Diener, Gaia Pigino , Karl Lechtreck
Publicado en: Journal of Cell Science, Edición 00219533, 2021, Página(s) jcs259010, ISSN 0021-9533
Editor: The Company of Biologists Ltd.
DOI: 10.1242/jcs.259010

Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport.

Autores: Nievergelt Adrian, Zykov Ilia, Diener Diener, Chhatre Aditya, Buchholz TimOliver, Delling Markus, Diez Stefan, Jug Florian, Štěpánek Ludek, Pigino Gaia.
Publicado en: Current Biology, Edición 09609822, 2022, Página(s) 4071-4078, ISSN 0960-9822
Editor: Cell Press
DOI: 10.1016/j.cub.2022.07.033

Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link

Autores: Rafał Bazan, Adam Schröfel, Ewa Joachimiak, Martyna Poprzeczko, Gaia Pigino, Dorota Wloga
Publicado en: PLOS Genetics, Edición 17/3, 2021, Página(s) e1009388, ISSN 1553-7404
Editor: Public Library of Science
DOI: 10.1371/journal.pgen.1009388

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