Self-organization of the cilium: the role of the tubulin code

Pubblicazioni

The structural basis of intraflagellar transport at a glance

Autori: Mareike A. Jordan, Gaia Pigino
Pubblicato in: Journal of Cell Science, Numero 00219533, 2021, Pagina/e jcs247163, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.247163

In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains.

Autori: van den Hoek H, Klena N, Jordan MA, Alvarez Viar Gonzalo, Righetto RD, Schaffer M, Erdmann PS, Wan W, Geimer S, Plitzko JM, Baumeister W, Pigino Gaia, Hamel V, Guichard P, Engel BD.
Pubblicato in: Science, Numero 00368075, 2022, Pagina/e 543-548, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.abm6704

The molecular structure of mammalian primary cilia revealed by cryo-electron tomography

Autori: Petra Kiesel, Gonzalo Alvarez Viar, Nikolai Tsoy, Riccardo Maraspini, Peter Gorilak, Vladimir Varga, Alf Honigmann, Gaia Pigino
Pubblicato in: Nature Structural & Molecular Biology, 2020, ISSN 1545-9993
Editore: Nature Publishing Group
DOI: 10.1038/s41594-020-0507-4

The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains

Autori: Samuel E Lacey, Helen E Foster, Gaia Pigino
Pubblicato in: Nature Structural Molecular Biology, 2023, ISSN 1545-9993
Editore: Nature Publishing Group
DOI: 10.1038/s41594-022-00905-5

Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility

Autori: Sudarshan Gadadhar, Gonzalo Alvarez Viar, Jan Niklas Hansen, An Gong, Aleksandr Kostarev, Côme Ialy-Radio, Sophie Leboucher, Marjorie Whitfield, Ahmed Ziyyat, Aminata Touré, Luis Alvarez, Gaia Pigino, Carsten Janke
Pubblicato in: Science, Numero 371/6525, 2021, Pagina/e all, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.abd4914

Structural Biology of Cilia and Intraflagellar Transport

Autori: Nikolai Klena, Gaia Pigino
Pubblicato in: Annual Review of Cell and Developmental Biology, 2022, ISSN 1081-0706
Editore: Annual Reviews, Inc.
DOI: 10.1146/annurev-cellbio-120219-034238

In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip

Autori: Jenna L. Wingfield, Betlehem Mekonnen, Ilaria Mengoni, Peiwei Liu,Mareike Jordan, Dennis Diener, Gaia Pigino , Karl Lechtreck
Pubblicato in: Journal of Cell Science, Numero 00219533, 2021, Pagina/e jcs259010, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.259010

Efficient precision editing of endogenous Chlamydomonas reinhardtii genes with CRISPR-Cas

Autori: Adrian Pascal Nievergelt, Dennis Ray Diener, Aliona Bogdanova, Thomas Brown, Gaia Pigino
Pubblicato in: Cell Reports Methods, 2023, ISSN 0346-251X
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.crmeth.2023.100562

Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport.

Autori: Nievergelt Adrian, Zykov Ilia, Diener Diener, Chhatre Aditya, Buchholz TimOliver, Delling Markus, Diez Stefan, Jug Florian, Štěpánek Ludek, Pigino Gaia.
Pubblicato in: Current Biology, Numero 09609822, 2022, Pagina/e 4071-4078, ISSN 0960-9822
Editore: Cell Press
DOI: 10.1016/j.cub.2022.07.033

Ccdc113/Ccdc96 complex, a novel regulator of ciliary beating that connects radial spoke 3 to dynein g and the nexin link

Autori: Rafał Bazan, Adam Schröfel, Ewa Joachimiak, Martyna Poprzeczko, Gaia Pigino, Dorota Wloga
Pubblicato in: PLOS Genetics, Numero 17/3, 2021, Pagina/e e1009388, ISSN 1553-7404
Editore: Public Library of Science
DOI: 10.1371/journal.pgen.1009388

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