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The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use

Deliverables

Review of health-economic approaches and design of a generic modelling framework

Review of health-economic approaches for diagnostic-driven antibiotic use and design of a generic modelling framework to be applied in this project (continuously updated between months 12 to 48)

Database business plan

Database business plan

Review of pricing and reimbursement policies for CA-ARTI-Dx

Review of pricing and reimbursement policies for CA-ARTI-Dx in at least 15 European countries in country briefs

Biobank business plan

Biobank business plan

VALUE-Dx Course

VALUE Dx Course, updated in motnhs 12 and 48

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Publications

Primary care for patients with respiratory tract infection before and early on in the COVID-19 pandemic: an observational study in 16 European countries

Author(s): Alike W van der Velden, Eva A Bax, Emily Bongard, Rune Munck Aabenhus, Marilena Anastasaki, Sibyl Anthierens, Anca Balan, Femke Böhmer, Pascale Bruno, Slawomir Chlabicz, Samuel Coenen, Annelies Colliers, Susanne Emmerich, Ana Garcia-Sangenis, Hrachuhi Ghazaryan, Sanne R van der Linde, Lile Malania, József Pauer, Angela Tomacinschii, Sarah Tonkin-Crine, Akke Vellinga, Ihor Zastavnyy, Theo Verheij
Published in: BMJ Open, 11/7, 2021, Page(s) e049257, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2021-049257

Health-Economic Analyses of Diagnostics: Guidance on Design and Reporting

Author(s): Simon van der Pol, Paula Rojas Garcia, Fernando Antoñanzas Villar, Maarten J. Postma, Antoinette D. I. van Asselt
Published in: PharmacoEconomics, 2021, ISSN 1170-7690
Publisher: Adis International Ltd.
DOI: 10.1007/s40273-021-01104-8

Efficiency of Diagnostic Testing for Helicobacter pylori Infections—A Systematic Review

Author(s): Paula Rojas García, Simon van der Pol, Antoinette D. I. van Asselt, Maarten Postma, Roberto Rodríguez-Ibeas, Carmelo A. Juárez-Castelló, Marino González, Fernando Antoñanzas
Published in: Antibiotics, 10/1, 2021, Page(s) 55, ISSN 2079-6382
Publisher: MDPI
DOI: 10.3390/antibiotics10010055

Economic Analyses of Respiratory Tract Infection Diagnostics: A Systematic Review

Author(s): Simon van der Pol, Paula Rojas Garcia, Maarten J. Postma, Fernando Antoñanzas Villar, Antoinette D. I. van Asselt
Published in: PharmacoEconomics, online, 2021, Page(s) online, ISSN 1170-7690
Publisher: Adis International Ltd.
DOI: 10.1007/s40273-021-01054-1

Nucleic acid amplification tests on respiratory samples for the diagnosis of coronavirus infections: a systematic review and meta-analysis

Author(s): Mona Mustafa Hellou, Anna Górska, Fulvia Mazzaferri, Eleonora Cremonini, Elisa Gentilotti, Pasquale De Nardo, Itamar Poran, Mariska M. Leeflang, Evelina Tacconelli, Mical Paul
Published in: Clinical Microbiology and Infection, 27/3, 2021, Page(s) 341-351, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2020.11.002

Multi-Criteria Decision Analysis to prioritize hospital admission of patients affected by COVID-19 in low-resource settings with hospital-bed shortage

Author(s): Pasquale De Nardo, Elisa Gentilotti, Fulvia Mazzaferri, Eleonora Cremonini, Paul Hansen, Herman Goossens, Evelina Tacconelli, E. Durante Mangoni, L.L. Florio, R. Zampino, F. Mele, I. Gentile, B. Pinchera, N. Coppola, M. Pisaturo, R. Luzzati, N. Petrosillo, E. Nicastri, A. Corpolongo, M.A. Cataldo, A. D’Abramo, G. Maffongelli, L. Scorzolini, C. Palazzolo, E. Boumis, A. Pan, A. D’Arminio Monfort
Published in: International Journal of Infectious Diseases, 98, 2020, Page(s) 494-500, ISSN 1201-9712
Publisher: Elsevier BV
DOI: 10.1016/j.ijid.2020.06.082

Point-of-care testing, antibiotic prescribing, and prescribing confidence for respiratory tract infections in primary care: a prospective audit in 18 European countries

Author(s): Alike W. van der Velden, Alma C. van de Pol, Emily Bongard, Daniela Cianci, Rune Aabenhus, Anca Balan, Femke Böhmer, Valerija Bralic Lang, Pascale Bruno, Slawomir Chlabicz, Samuel Coenen, Annelies Colliers, Anna Garcia-Sangenis, Hrachuhi Ghazaryan, Mciek Godycki-Cwirko , Siri Jensen, Christos Lionis, Sanne van der Linde, Lile Malania, Jozsef Pauer, Angela Tomacinschii, Akke Vellinga, Ihor Zastavn
Published in: BGJP Open, 2021
Publisher: Royal College of General Practitioners
DOI: 10.3399/bjgpo.2021.0212

Using point-of-care diagnostic testing for improved antibiotic prescription: an economic model

Author(s): Antoñanzas F, Juárez C, Rodríguez R
Published in: Health Economics Review, 2021
Publisher: Nature Springer
DOI: 10.1186/s13561-021-00326-y

Diagnostic Testing for Sepsis: A Systematic Review of Economic Evaluations

Author(s): Rojas García P, van der Pol S, van Asselt ADI, et al.
Published in: Antibiotics, 2022
Publisher: MDPI
DOI: 10.3390/antibiotics11010027

Systematic review and meta-analysis of diagnostics accuracy in community-acquired acute respiratory tract infections (protocol)

Author(s): Pasquale De Nardo, Elisa Gentilotti, Eleonora Cremonini, Fulvia Mazzaferri, Anna Gorska, Evelina Tacconelli, Mical Paul, Muna Mustafa, Till Bachmann, Christopher Butler, Samuel Coenen, Gail Hayward, Jorge Villacian, Herman Goossens, Itamar Poran
Published in: PROSPERO - International Prospective Register of Systematic Reviews, 2019
Publisher: National Institute for Health Research - University of York

Does diagnostic testing always decrease antibiotics prescriptions?

Author(s): F. Antoñanzas, C. A. Juárez‑Castelló, R. Rodríguez‑Ibeas
Published in: The European Journal of Health Economics, 2022
Publisher: Springer Nature
DOI: 10.1007/s10198-022-01488-0

Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections. A systematic review and meta-analysis

Author(s): Gentilotti, E. et al
Published in: Clinical Microbiology and Infection, 2021
Publisher: ESCMID
DOI: 10.1016/j.cmi.2021.09.025

Utilising long-read shotgun sequencing to study the lower respiratory tract microbiome from endotracheal aspirate samples

Author(s): Juan Pablo Rodriguez Ruiz, Minh Nguyen Ngoc, Basil Britto Xavier, Jasmine Coppens, Christine Lammens, Veerle Matheeussen, Herman Goossens, Surbhi Malhotra-Kumar
Published in: 30th ECCMID abstract book, annual, 2020, Page(s) 2455
Publisher: ESCMID

Meta-analysis of accuracy of rapid influenza antigen detection tests in community-care settings accounting for antigen type, setting, population and manufacturer

Author(s): Elisa Gentilotti, Eleonora Cremonini, Pasquale De Nardo, Anna Gorska, Fulvia Mazzaferri, Mical Paul, Herman Goossens, Evelina Tacconelli
Published in: 30th ECCMID abstract book, annual, 2020, Page(s) 2227
Publisher: ESCMID