CARdiomyopathy in type 2 DIAbetes mellitus

Project Information

CARDIATEAM

Grant agreement ID: 821508

DOI

10.3030/821508

Project closed

EC signature date 11 April 2019

Start date 1 March 2019

End date 28 February 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost

€ 12 906 216,05

EU contribution

€ 6 700 000,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (2)

Initial data management plan
Update of data management plan

Documents, reports (1)

Recommendations for preclinical DCM bio-imaging

Publications

Peer reviewed articles (11)

Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.

Author(s): Serena Zacchigna; Alessia Paldino; Inês Falcão-Pires; Evangelos P. Daskalopoulos; Matteo Dal Ferro; Simone Vodret; Pierluigi Lesizza; Antonio Cannatà; Daniela Miranda-Silva; André P. Lourenço; Bruno Pinamonti; Gianfranco Sinagra; Florian Weinberger; Thomas Eschenhagen; Lucie Carrier; Izhak Kehat; Carlo G. Tocchetti; Michele Russo; Michele Russo; Alessandra Ghigo; James Cimino; Emilio Hirsch;
Published in: Zacchigna , S , Paldino , A , Falcão-Pires , I , Daskalopoulos , E P , Dal Ferro , M , Vodret , S , Lesizza , P , Cannatà , A , Miranda-Silva , D , Lourenço , A P , Pinamonti , B , Sinagra , G , Weinberger , F , Eschenhagen , T , Carrier , L , Kehat , I , Tocchetti , C G , Russo , M , Ghigo , A , Cimino , J , Hirsch , E , Dawson , D , Ciccarelli , M , Oliveti , M , Linke , W A , Cuijpers , I ,, Issue 2, 2020, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvaa110

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

Author(s): Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy Adamski, Christian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alder
Published in: Cardiovascular Diabetology, Issue 23, 2024, ISSN 1475-2840
Publisher: BioMed Central
DOI: 10.1186/s12933-024-02288-x

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Author(s): Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson
Published in: Diabetes/Metabolism Research and Reviews, Issue 41, 2025, ISSN 1520-7552
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/dmrr.70081

Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review

Author(s): 2. Henkens MTHM, Remmelzwaal S, Robinson EL, van Ballegooijen AJ, Barandiarán Aizpurua A, Verdonschot JAJ, Raafs AG, Weerts J, Hazebroek MR, Sanders-van Wijk S, Handoko ML, den Ruijter HM, Lam CSP, de Boer RA, Paulus WJ, van Empel VPM, Vos R, Brunner-La Rocca HP, Beulens JWJ, Heymans SRB
Published in: Eur J Heart Fail., 2020, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.1944

Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts

Author(s): Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J Grabe, Cornelia Prehn, Jerzy Adamski, Karsten Suhre, Wolfgang Rathmann, Andreas Ruepp, Johannes Hertel, Annette Peters, Rui Wang-Sattler
Published in: Cardiovascular Diabetology, 2023, ISSN 1475-2840
Publisher: BioMed Central
DOI: 10.1186/s12933-023-01862-z

Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function

Author(s): Shixiang Yu, Siyu Han, Mengya Shi, Makoto Harada, Jianhong Ge, Xuening Li, Xiang Cai, Margit Heier, Gabi Karstenmüller, Karsten Suhre, Christian Gieger, Wolfgang Koenig, Wolfgang Rathmann, Annette Peters, Rui Wang-Sattler
Published in: Metabolites, Issue 14, 2025, Page(s) 258, ISSN 2218-1989
Publisher: MDPI AG
DOI: 10.3390/metabo14050258

Integrative Metabolomics of Targeted and Nontargeted Analyses in T2D Progression

Author(s): Jianhong Ge, Siyu Han, Mengya Shi, Makoto Harada, Shixiang Yu, Jiaqi Zheng, Cornelia Prehn, Jerzy Adamski, Gabi Kastenmüller, Sabrina Schlesinger, Wolfgang Koenig, Birgit Linkohr, Barbara Thorand, Karsten Suhre, Christian Gieger, Annette Peters, Rui Wang-Sattler
Published in: Diabetes Care, Issue 49, 2026, Page(s) 282-291, ISSN 0149-5992
Publisher: American Diabetes Association
DOI: 10.2337/dc25-1707

TIGER: technical variation elimination for metabolomics data using ensemble learning architecture

Author(s): Han S, Huang J, Foppiano F, Prehn C, Adamski J, Suhre K, Li Y, Matullo G, Schliess F, Gieger C, Peters A, Wang-Sattler R.
Published in: Briefings in Bioinformatics, 2022, ISSN 1467-5463
Publisher: Oxford University Press
DOI: 10.1093/bib/bbab535

The need for adjusting experimental models to meet clinical reality.

Author(s): Lezoualc'h F, Badimon L, Baker H, Bernard M, Czibik G, de Boer RA, D'Humières T, Kergoat M, Kowala M, Rieusset J, Vilahur G, Détrait M, Watson C, Derumeaux GA.
Published in: Cardivascular Research, 2022, ISSN 0009-7322
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1093/cvr/cvac152

LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer

Author(s): Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-58314-3

Urea cycle modulation by combined SGLT2 inhibitors and metformin

Author(s): Makoto Harada, Jonathan Adam, Siyu Han, Mengya Shi, Jianhong Ge, Jutta Lintelmann, Alexander Cecil, Sven Zukunft, Cornelia Prehn, Michael Witting, Markus F. Scheerer, Susanne Neschen, Martin Irmler, Johannes Beckers, Jerzy Adamski, Daniel Teupser, Birgit Linkohr, Christian Gieger, Martin Hrabě de Angelis, Annette Peters, Rui Wang-Sattler
Published in: BMC Medicine, Issue 24, 2026, ISSN 1741-7015
Publisher: BioMed Central
DOI: 10.1186/s12916-025-04609-7

Non-peer reviewed articles (1)

Missing view completion for multi-timepoints omics data via representation disentanglement and temporal knowledge transfer

Author(s): Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Published in: Nature Machine Intelligence, 2023, ISSN 2522-5839
Publisher: CSH
DOI: 10.1101/2023.09.26.559302

Other (1)

current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart

Author(s): van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; Brundel, Bianca; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M; Dendorfer, Andreas; Duncker, Dirk J; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü
Published in: Cardiovascular Research, 118(15), 3016 - 3051. Oxford University Press, Issue 3, 2022
Publisher: Oxford academic
DOI: 10.1093/cvr/cvab370