CARdiomyopathy in type 2 DIAbetes mellitus

Información del proyecto

CARDIATEAM

Identificador del acuerdo de subvención: 821508

DOI

10.3030/821508

Proyecto cerrado

Fecha de la firma de la CE 11 Abril 2019

Fecha de inicio 1 Marzo 2019

Fecha de finalización 28 Febrero 2026

Financiado con arreglo a

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coste total

€ 12 906 216,05

Aportación de la UE

€ 6 700 000,00

Coordinado por

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Open Research Data Pilot (2)

Initial data management plan
Update of data management plan

Documents, reports (1)

Recommendations for preclinical DCM bio-imaging

Publicaciones

Peer reviewed articles (11)

Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.

Autores: Serena Zacchigna; Alessia Paldino; Inês Falcão-Pires; Evangelos P. Daskalopoulos; Matteo Dal Ferro; Simone Vodret; Pierluigi Lesizza; Antonio Cannatà; Daniela Miranda-Silva; André P. Lourenço; Bruno Pinamonti; Gianfranco Sinagra; Florian Weinberger; Thomas Eschenhagen; Lucie Carrier; Izhak Kehat; Carlo G. Tocchetti; Michele Russo; Michele Russo; Alessandra Ghigo; James Cimino; Emilio Hirsch;
Publicado en: Zacchigna , S , Paldino , A , Falcão-Pires , I , Daskalopoulos , E P , Dal Ferro , M , Vodret , S , Lesizza , P , Cannatà , A , Miranda-Silva , D , Lourenço , A P , Pinamonti , B , Sinagra , G , Weinberger , F , Eschenhagen , T , Carrier , L , Kehat , I , Tocchetti , C G , Russo , M , Ghigo , A , Cimino , J , Hirsch , E , Dawson , D , Ciccarelli , M , Oliveti , M , Linke , W A , Cuijpers , I ,, Edición 2, 2020, ISSN 0008-6363
Editor: Elsevier BV
DOI: 10.1093/cvr/cvaa110

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

Autores: Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy Adamski, Christian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alder
Publicado en: Cardiovascular Diabetology, Edición 23, 2024, ISSN 1475-2840
Editor: BioMed Central
DOI: 10.1186/s12933-024-02288-x

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Autores: Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson
Publicado en: Diabetes/Metabolism Research and Reviews, Edición 41, 2025, ISSN 1520-7552
Editor: John Wiley & Sons Inc.
DOI: 10.1002/dmrr.70081

Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review

Autores: 2. Henkens MTHM, Remmelzwaal S, Robinson EL, van Ballegooijen AJ, Barandiarán Aizpurua A, Verdonschot JAJ, Raafs AG, Weerts J, Hazebroek MR, Sanders-van Wijk S, Handoko ML, den Ruijter HM, Lam CSP, de Boer RA, Paulus WJ, van Empel VPM, Vos R, Brunner-La Rocca HP, Beulens JWJ, Heymans SRB
Publicado en: Eur J Heart Fail., 2020, ISSN 1388-9842
Editor: Elsevier BV
DOI: 10.1002/ejhf.1944

Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts

Autores: Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J Grabe, Cornelia Prehn, Jerzy Adamski, Karsten Suhre, Wolfgang Rathmann, Andreas Ruepp, Johannes Hertel, Annette Peters, Rui Wang-Sattler
Publicado en: Cardiovascular Diabetology, 2023, ISSN 1475-2840
Editor: BioMed Central
DOI: 10.1186/s12933-023-01862-z

Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function

Autores: Shixiang Yu, Siyu Han, Mengya Shi, Makoto Harada, Jianhong Ge, Xuening Li, Xiang Cai, Margit Heier, Gabi Karstenmüller, Karsten Suhre, Christian Gieger, Wolfgang Koenig, Wolfgang Rathmann, Annette Peters, Rui Wang-Sattler
Publicado en: Metabolites, Edición 14, 2025, Página(s) 258, ISSN 2218-1989
Editor: MDPI AG
DOI: 10.3390/metabo14050258

Integrative Metabolomics of Targeted and Nontargeted Analyses in T2D Progression

Autores: Jianhong Ge, Siyu Han, Mengya Shi, Makoto Harada, Shixiang Yu, Jiaqi Zheng, Cornelia Prehn, Jerzy Adamski, Gabi Kastenmüller, Sabrina Schlesinger, Wolfgang Koenig, Birgit Linkohr, Barbara Thorand, Karsten Suhre, Christian Gieger, Annette Peters, Rui Wang-Sattler
Publicado en: Diabetes Care, Edición 49, 2026, Página(s) 282-291, ISSN 0149-5992
Editor: American Diabetes Association
DOI: 10.2337/dc25-1707

TIGER: technical variation elimination for metabolomics data using ensemble learning architecture

Autores: Han S, Huang J, Foppiano F, Prehn C, Adamski J, Suhre K, Li Y, Matullo G, Schliess F, Gieger C, Peters A, Wang-Sattler R.
Publicado en: Briefings in Bioinformatics, 2022, ISSN 1467-5463
Editor: Oxford University Press
DOI: 10.1093/bib/bbab535

The need for adjusting experimental models to meet clinical reality.

Autores: Lezoualc'h F, Badimon L, Baker H, Bernard M, Czibik G, de Boer RA, D'Humières T, Kergoat M, Kowala M, Rieusset J, Vilahur G, Détrait M, Watson C, Derumeaux GA.
Publicado en: Cardivascular Research, 2022, ISSN 0009-7322
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1093/cvr/cvac152

LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer

Autores: Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Publicado en: Nature Communications, Edición 16, 2025, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-025-58314-3

Urea cycle modulation by combined SGLT2 inhibitors and metformin

Autores: Makoto Harada, Jonathan Adam, Siyu Han, Mengya Shi, Jianhong Ge, Jutta Lintelmann, Alexander Cecil, Sven Zukunft, Cornelia Prehn, Michael Witting, Markus F. Scheerer, Susanne Neschen, Martin Irmler, Johannes Beckers, Jerzy Adamski, Daniel Teupser, Birgit Linkohr, Christian Gieger, Martin Hrabě de Angelis, Annette Peters, Rui Wang-Sattler
Publicado en: BMC Medicine, Edición 24, 2026, ISSN 1741-7015
Editor: BioMed Central
DOI: 10.1186/s12916-025-04609-7

Non-peer reviewed articles (1)

Missing view completion for multi-timepoints omics data via representation disentanglement and temporal knowledge transfer

Autores: Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Publicado en: Nature Machine Intelligence, 2023, ISSN 2522-5839
Editor: CSH
DOI: 10.1101/2023.09.26.559302

Other (1)

current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart

Autores: van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; Brundel, Bianca; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M; Dendorfer, Andreas; Duncker, Dirk J; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü
Publicado en: Cardiovascular Research, 118(15), 3016 - 3051. Oxford University Press, Edición 3, 2022
Editor: Oxford academic
DOI: 10.1093/cvr/cvab370