CARdiomyopathy in type 2 DIAbetes mellitus

Informazioni relative al progetto

CARDIATEAM

ID dell’accordo di sovvenzione: 821508

DOI

10.3030/821508

Progetto chiuso

Data della firma CE 11 Aprile 2019

Data di avvio 1 Marzo 2019

Data di completamento 28 Febbraio 2026

Finanziato da

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Costo totale

€ 12 906 216,05

Contributo UE

€ 6 700 000,00

Coordinato da

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Open Research Data Pilot (2)

Initial data management plan
Update of data management plan

Documents, reports (1)

Recommendations for preclinical DCM bio-imaging

Pubblicazioni

Peer reviewed articles (11)

Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function.

Autori: Serena Zacchigna; Alessia Paldino; Inês Falcão-Pires; Evangelos P. Daskalopoulos; Matteo Dal Ferro; Simone Vodret; Pierluigi Lesizza; Antonio Cannatà; Daniela Miranda-Silva; André P. Lourenço; Bruno Pinamonti; Gianfranco Sinagra; Florian Weinberger; Thomas Eschenhagen; Lucie Carrier; Izhak Kehat; Carlo G. Tocchetti; Michele Russo; Michele Russo; Alessandra Ghigo; James Cimino; Emilio Hirsch;
Pubblicato in: Zacchigna , S , Paldino , A , Falcão-Pires , I , Daskalopoulos , E P , Dal Ferro , M , Vodret , S , Lesizza , P , Cannatà , A , Miranda-Silva , D , Lourenço , A P , Pinamonti , B , Sinagra , G , Weinberger , F , Eschenhagen , T , Carrier , L , Kehat , I , Tocchetti , C G , Russo , M , Ghigo , A , Cimino , J , Hirsch , E , Dawson , D , Ciccarelli , M , Oliveti , M , Linke , W A , Cuijpers , I ,, Numero 2, 2020, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvaa110

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i

Autori: Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy Adamski, Christian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alder
Pubblicato in: Cardiovascular Diabetology, Numero 23, 2024, ISSN 1475-2840
Editore: BioMed Central
DOI: 10.1186/s12933-024-02288-x

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Autori: Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson
Pubblicato in: Diabetes/Metabolism Research and Reviews, Numero 41, 2025, ISSN 1520-7552
Editore: John Wiley & Sons Inc.
DOI: 10.1002/dmrr.70081

Risk of bias in studies investigating novel diagnostic biomarkers for heart failure with preserved ejection fraction. A systematic review

Autori: 2. Henkens MTHM, Remmelzwaal S, Robinson EL, van Ballegooijen AJ, Barandiarán Aizpurua A, Verdonschot JAJ, Raafs AG, Weerts J, Hazebroek MR, Sanders-van Wijk S, Handoko ML, den Ruijter HM, Lam CSP, de Boer RA, Paulus WJ, van Empel VPM, Vos R, Brunner-La Rocca HP, Beulens JWJ, Heymans SRB
Pubblicato in: Eur J Heart Fail., 2020, ISSN 1388-9842
Editore: Elsevier BV
DOI: 10.1002/ejhf.1944

Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts

Autori: Mengya Shi, Siyu Han, Kristin Klier, Gisela Fobo, Corinna Montrone, Shixiang Yu, Makoto Harada, Ann-Kristin Henning, Nele Friedrich, Martin Bahls, Marcus Dörr, Matthias Nauck, Henry Völzke, Georg Homuth, Hans J Grabe, Cornelia Prehn, Jerzy Adamski, Karsten Suhre, Wolfgang Rathmann, Andreas Ruepp, Johannes Hertel, Annette Peters, Rui Wang-Sattler
Pubblicato in: Cardiovascular Diabetology, 2023, ISSN 1475-2840
Editore: BioMed Central
DOI: 10.1186/s12933-023-01862-z

Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function

Autori: Shixiang Yu, Siyu Han, Mengya Shi, Makoto Harada, Jianhong Ge, Xuening Li, Xiang Cai, Margit Heier, Gabi Karstenmüller, Karsten Suhre, Christian Gieger, Wolfgang Koenig, Wolfgang Rathmann, Annette Peters, Rui Wang-Sattler
Pubblicato in: Metabolites, Numero 14, 2025, Pagina/e 258, ISSN 2218-1989
Editore: MDPI AG
DOI: 10.3390/metabo14050258

Integrative Metabolomics of Targeted and Nontargeted Analyses in T2D Progression

Autori: Jianhong Ge, Siyu Han, Mengya Shi, Makoto Harada, Shixiang Yu, Jiaqi Zheng, Cornelia Prehn, Jerzy Adamski, Gabi Kastenmüller, Sabrina Schlesinger, Wolfgang Koenig, Birgit Linkohr, Barbara Thorand, Karsten Suhre, Christian Gieger, Annette Peters, Rui Wang-Sattler
Pubblicato in: Diabetes Care, Numero 49, 2026, Pagina/e 282-291, ISSN 0149-5992
Editore: American Diabetes Association
DOI: 10.2337/dc25-1707

TIGER: technical variation elimination for metabolomics data using ensemble learning architecture

Autori: Han S, Huang J, Foppiano F, Prehn C, Adamski J, Suhre K, Li Y, Matullo G, Schliess F, Gieger C, Peters A, Wang-Sattler R.
Pubblicato in: Briefings in Bioinformatics, 2022, ISSN 1467-5463
Editore: Oxford University Press
DOI: 10.1093/bib/bbab535

The need for adjusting experimental models to meet clinical reality.

Autori: Lezoualc'h F, Badimon L, Baker H, Bernard M, Czibik G, de Boer RA, D'Humières T, Kergoat M, Kowala M, Rieusset J, Vilahur G, Détrait M, Watson C, Derumeaux GA.
Pubblicato in: Cardivascular Research, 2022, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1093/cvr/cvac152

LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer

Autori: Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-58314-3

Urea cycle modulation by combined SGLT2 inhibitors and metformin

Autori: Makoto Harada, Jonathan Adam, Siyu Han, Mengya Shi, Jianhong Ge, Jutta Lintelmann, Alexander Cecil, Sven Zukunft, Cornelia Prehn, Michael Witting, Markus F. Scheerer, Susanne Neschen, Martin Irmler, Johannes Beckers, Jerzy Adamski, Daniel Teupser, Birgit Linkohr, Christian Gieger, Martin Hrabě de Angelis, Annette Peters, Rui Wang-Sattler
Pubblicato in: BMC Medicine, Numero 24, 2026, ISSN 1741-7015
Editore: BioMed Central
DOI: 10.1186/s12916-025-04609-7

Non-peer reviewed articles (1)

Missing view completion for multi-timepoints omics data via representation disentanglement and temporal knowledge transfer

Autori: Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler
Pubblicato in: Nature Machine Intelligence, 2023, ISSN 2522-5839
Editore: CSH
DOI: 10.1101/2023.09.26.559302

Other (1)

current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart

Autori: van der Velden, Jolanda; Asselbergs, Folkert W; Bakkers, Jeroen; Batkai, Sandor; Bertrand, Luc; Bezzina, Connie R; Bot, Ilze; Brundel, Bianca; Carrier, Lucie; Chamuleau, Steven; Ciccarelli, Michele; Dawson, Dana; Davidson, Sean M; Dendorfer, Andreas; Duncker, Dirk J; Eschenhagen, Thomas; Fabritz, Larissa; Falcão-Pires, Ines; Ferdinandy, Péter; Giacca, Mauro; Girao, Henrique; Gollmann-Tepeköylü
Pubblicato in: Cardiovascular Research, 118(15), 3016 - 3051. Oxford University Press, Numero 3, 2022
Editore: Oxford academic
DOI: 10.1093/cvr/cvab370