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Neurotoxicity De-Risking in Preclinical Drug Discovery

Project description

A platform for predicting neurotoxicity of drug candidates

Many drug candidates can introduce toxicity in the central nervous system, which can be poorly predicted during the research and development process. To address this problem, the EU-funded NeuroDeRisk project will study the mechanisms of neurotoxicity, specifically manifested as seizures, psychiatric changes and peripheral neuropathies. Researchers will develop a platform that integrates biological models, artificial intelligence, biomarkers, omics data and compound design tools to improve risk-assessment during the drug development pipeline. This platform will support decision-making in the pharmaceutical industry, offering better protection of human volunteers and patients.

Coordinator

UNIVERSITAT WIEN
Net EU contribution
€ 594 450,00
Address
Universitatsring 1
1010 Wien
Austria
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 7 425,00

Participants (17)

MEDIZINISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 372 200,00
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 5 300,00
FARMACEUTSKI FAKULTET UNIVERZITETAU BEOGRADU
Serbia
Net EU contribution
€ 696 150,00
Address
Vojvode Stepe 450
52600 Belgrade
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 9 850,00
INTE:LIGAND SOFTWARE-ENTWICKLUNGS-UND CONSULTING GMBH
Austria
Net EU contribution
€ 341 400,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Clemens Maria Hofbauer Gasse 6
2344 Maria Enzersdorf
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 4 850,00
ITA-SUOMEN YLIOPISTO
Finland
Net EU contribution
€ 804 900,00
Address
Yliopistonranta 1 E
70211 Kuopio
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 11 412,50
Region
Manner-Suomi Pohjois- ja Itä-Suomi Pohjois-Savo
UNIVERSITA DEGLI STUDI DI FIRENZE
Italy
Net EU contribution
€ 391 500,00
Address
Piazza San Marco 4
50121 Florence
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 5 562,50
ICETA INSTITUTO DE CIENCIAS, TECNOLOGIAS E AGROAMBIENTE DA UNIVERSIDADE DO PORTO
Portugal
Net EU contribution
€ 403 500,00
Address
Rua D Manuel Ii Apartado 55142
4051 401 Porto
Activity type
Research Organisations
Non-EU contribution
€ 5 687,50
Region
Continente Norte Área Metropolitana do Porto
 
UPPSALA UNIVERSITET
Sweden
Net EU contribution
€ 307 400,00
Address
Von Kraemers Alle 4
751 05 Uppsala
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 4 350,00
Region
Östra Sverige Östra Mellansverige Uppsala län
ALCEDIAG
France
Net EU contribution
€ 583 300,00
Address
Route Des Michels La Corneirelle
13790 Peynier
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 8 262,50
UNIVERSITE CLERMONT AUVERGNE
France
Net EU contribution
€ 429 400,00
Address
49 Bd Francois Mitterrand
63000 Clermont Ferrand
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 6 100,00
Region
Auvergne-Rhône-Alpes Auvergne Puy-de-Dôme
 
A. PERSIDIS & SIA OE
Greece
Net EU contribution
€ 406 800,00
SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Address
Rodopoleos Street 34
167 77 Athina
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 5 762,50
Region
Νότιος Τομέας Αθηνών Aττική Αττική
SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT
France
Net EU contribution
€ 0,00
Address
Pierre Brossolette 1
91380 Chilly Mazarin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 1 613 000,00
ASTRAZENECA AB
Sweden
Net EU contribution
€ 0,00
Address
Vastra Maelarhamnen
151 85 Sodertaelje
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 185 000,00
FUJIFILM CELLULAR DYNAMICS INC
United States
Net EU contribution
€ 0,00
Address
Science Drive 525 Suite 200
53711 Madison Wi
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 600 000,00
MERCK SHARP & DOHME CORP
United States
Net EU contribution
€ 0,00
Address
One Merck Drive
08889 Whitehouse Station Nj
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 638 500,00
NOVARTIS PHARMA AG
Switzerland
Net EU contribution
€ 0,00
Address
Lichtstrasse 35
4056 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 1 100 000,00
Region
Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt
PFIZER LIMITED
United Kingdom
Net EU contribution
€ 0,00
Address
Ramsgate Road
CT13 9NJ Sandwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 75 000,00
UCB BIOPHARMA
Belgium
Net EU contribution
€ 0,00
Address
Allee De La Recherche 60
1070 Bruxelles
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 135 000,00
Region
Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest