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CORDIS - EU research results
CORDIS

Membrane protein integrated technologies development for drug design

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Prometeus web site (opens in new window)

The website will present the project to the wider public and give detailed, tailored information on, e.g., project progress, activities and results. The website will also contain: 1) a dedicated section for society at large, in which project activities are presented in a language understandable to non-experts; b) a private area – accessible only to partners– for the exchange of working documents. The PMT will be responsible for the creation and updating of the website.

Final Conference (opens in new window)

The Final Conference will be open to the public and it will report the scientific and technological results obtained during the Action

Workshop on Membrane proteins (opens in new window)

WP6 will include the organization of a 2-day practical multi-disciplinary Workshop on “Membrane proteins: strategies for production, stabilization and structural analysis”.

Publications

Small-angle scattering from flat bilayers containing correlated scattering length density inhomogeneities (opens in new window)

Author(s): Francesco Spinozzi, Leandro R. S. Barbosa, Giacomo Corucci, Paolo Mariani and Rosangela Itri
Published in: Journal of Applied Crystallography, Issue 2023, 56, 2023, Page(s) 1348-1360, ISSN 1600-5767
Publisher: International Union of Crystallography
DOI: 10.1107/s1600576723006143

SAXS Reveals the Stabilization Effects of Modified Sugars on Model Proteins (opens in new window)

Author(s): Astra Piccinini, Eva C. Lourenço, Osvaldo S. Ascenso, Maria Rita Ventura, Heinz Amenitsch, Paolo Moretti, Paolo Mariani, Maria Grazia Ortore and Francesco Spinozzi
Published in: Life, Issue 12(1), 15 January 2022, 2022, Page(s) 123, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life12010123

Small-Angle Neutron Scattering Reveals the Nanostructure of Liposomes with Embedded OprF Porins of Pseudomonas aeruginosa. (opens in new window)

Author(s): Spinozzi F, Alcaraz JP, Ortore MG, Gayet L, Radulescu A, Martin DK, Maccarini M.
Published in: Langmuir, 2022, Page(s) 15026-15037, ISSN 1520-5827
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.2c01342

Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis (opens in new window)

Author(s): Yong Zi Tan, José Rodrigues, James E. Keener, Ruixiang Blake Zheng, Richard Brunton, Brian Kloss, Sabrina I. Giacometti, Ana L. Rosário, Lei Zhang, Michael Niederweis, Oliver B. Clarke, Todd L. Lowary, Michael T. Marty, Margarida Archer, Clinton S. Potter, Bridget Carragher, Filippo Mancia
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-17202-8

Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate. (opens in new window)

Author(s): Giacomo Parisi; Giacomo Parisi; Ida Freda; Cécile Exertier; Cristina Cecchetti; Cristina Cecchetti; Elena Gugole; Gabriele Cerutti; Gabriele Cerutti; Lucia D'Auria; Alberto Macone; Beatrice Vallone; C. Savino; Linda Celeste Montemiglio
Published in: Biomolecules, Issue 1, 2022, Page(s) 1411, ISSN 2218-273X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/biom10101411

High Throughput Expression Screening of Arabinofuranosyltransferases from Mycobacteria (opens in new window)

Author(s): José Rodrigues, Vanessa T. Almeida, Ana L. Rosário, Yong Zi Tan, Brian Kloss, Filippo Mancia, Margarida Archer
Published in: Processes, Issue 9/4, 2021, Page(s) 629, ISSN 2227-9717
Publisher: MDPI
DOI: 10.3390/pr9040629

Cryo-EM structure of the human ferritin–transferrin receptor 1 complex (opens in new window)

Author(s): Linda Celeste Montemiglio, Claudia Testi, Pierpaolo Ceci, Elisabetta Falvo, Martina Pitea, Carmelinda Savino, Alessandro Arcovito, Giovanna Peruzzi, Paola Baiocco, Filippo Mancia, Alberto Boffi, Amédée des Georges, Beatrice Vallone
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-09098-w

Cryo-EM Structures and Regulation of Arabinofuranosyltransferase AftD from Mycobacteria (opens in new window)

Author(s): Yong Zi Tan, Lei Zhang, José Rodrigues, Ruixiang Blake Zheng, Sabrina I. Giacometti, Ana L. Rosário, Brian Kloss, Venkata P. Dandey, Hui Wei, Richard Brunton, Ashleigh M. Raczkowski, Diogo Athayde, Maria João Catalão, Madalena Pimentel, Oliver B. Clarke, Todd L. Lowary, Margarida Archer, Michael Niederweis, Clinton S. Potter, Bridget Carragher, Filippo Mancia
Published in: Molecular Cell, Issue 78/4, 2020, Page(s) 683-699.e11, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.04.014

The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors (opens in new window)

Author(s): Lucia Silvestrini, Norhan Belhaj, Lucia Comez, Yuri Gerelli, Antonino Lauria, Valeria Libera, Paolo Mariani, Paola Marzullo, Maria Grazia Ortore, Antonio Palumbo Piccionello, Caterina Petrillo, Lucrezia Savini, Alessandro Paciaroni, Francesco Spinozzi
Published in: Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-88630-9

Secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon mRNA vaccination (opens in new window)

Author(s): Juliana Gonçalves, Margarida Juliano, Nádia Charepe, Marta Alenquer, Diogo Athayde, Filipe Ferreira, Margarida Archer, Maria João Amorim, Fátima Serrano, Helena Soares
Published in: Cell Reports Medicine, Issue Volume 2, Issue 12, 21 December 2021, 2021, Page(s) 100468, ISSN 2666-3791
Publisher: Cell Press
DOI: 10.1016/j.xcrm.2021.100468

Stabilization of the Dimeric State of SARS-CoV-2 Main Protease by GC376 and Nirmatrelvir (opens in new window)

Author(s): Alessandro Paciaroni; Valeria Libera; Francesca Ripanti; Andrea Orecchini; Caterina Petrillo; Daniela Francisci; Elisabetta Schiaroli; Samuele Sabbatini; Anna Gidari; Elisa Bianconi; Antonio Macchiarulo; Rohanah Hussain; Lucia Silvestrini; Paolo Moretti; Norhan Belhaj; Matteo Vercelli; Yessica Roque; Paolo Mariani; Lucia Comez; Francesco Spinozzi
Published in: International Journal of Molecular Sciences, Issue 24, 2023, Page(s) 6062, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076062

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