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Soft Biocompatible Polymeric Nanostructures: A Toolbox for Novel Generation of Nano Pharmaceuticals in Ophthalmology

Deliverables

Theoretical prediction of the relationships between topology and composition of multi-responsive nanogels and character of stimuli-induced volume transitions

A report describing the theoretical prediction of the relationships between polymer topology and composition of the multiresponsive nanogels and their stimuliinduced volume transitions will be prepared and submitted

Project Website

The deliverable is related to the setup and update of the project website for the whole duration of the project.

Publications

Non-linear elasticity effects and stratification in brushes of branched polyelectrolytes

Author(s): Lebedeva I.O.; Shavykin O.V.; Neelov I.M.; Zhulina E.B.; Leermakers F.A.M.; Borisov, O.V
Published in: Journal of Chemical Physics, 2019, Page(s) 2014902, ISSN 0021-9606
Publisher: American Institute of Physics
DOI: 10.1063/1.5130580

Temperature and Salt Responsivity of Anionic, Cationic and Amphoteric Nanogels Based on N-Isopropylacrylamide, 2-Acrylamido-2-Methyl-1-Propanesulfonic Acid Sodium Salt and (3-Acrylamidopropyl) Trimethylammonium Chloride

Author(s): Aigerim Ye. Ayazbayeva, Alexey V. Shakhvorostov1, Sarkyt E. Kudaibergenov
Published in: Bulletin of the University of Karaganda Chemistry, Issue 108 (4), 2022, Page(s) 14-24, ISSN 2518-718X
Publisher: Academician Ye.A. Buketov Karaganda University
DOI: 10.31489/2022ch4/4-22-15

Anionic Polysaccharide – Gellan As Perspective Polymer for Potential Application in Medicine and Oil Recovery: A Mini-Review

Author(s): S.E. Kudaibergenov, Gulnur Tatykhanova, N.N. Gizatullina, R.N. Tuleyeva, D.B. Kaldybekov, I.Sh. Gussenov, R.Zh. Berzhanova, T.D. Mukasheva, Maria Vamvakaki, Vladimir Aseyev, Vitaliy V. Khutoryanskiy
Published in: Uzbekistan Journal of Polymers, Issue 2 (2), 2023, Page(s) 39-56, ISSN 2181-3256
Publisher: Institute of Chemistry and Physics of Polymers of the Academy of Sciences of the Republic of Uzbekistan

Tough Materials Through Ionic Interactions

Author(s): Linda Salminen, Erno Karjalainen, Vladimir Aseyev, Heikki Tenhu
Published in: Frontiers in Chemistry, Issue 9, 2021, Page(s) 721656, ISSN 2296-2646
Publisher: Frontiers
DOI: 10.3389/fchem.2021.721656

Poly(2-ethyl-2-oxazoline) grafted gellan gum for potential application in transmucosal drug delivery

Author(s): Janni Lavikainen, Moldir Dauletbekova, Gaukhar Toleutay, Maria Kaliva, Maria Chatzinikolaidou, Sarkyt E. Kudaibergenov, Andrey Tenkovtsev, Vitaliy V. Khutoryanskiy, Maria Vamvakaki, Vladimir Aseyev
Published in: Polymers for Advanced Technologies, Issue 32 (7), 2021, Page(s) 2770-2780, ISSN 1042-7147
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/pat.5298

Synthesis and characterization of novel thermo- and salt-sensitive amphoteric terpolymers based on acrylamide derivatives

Author(s): A.Ye. Ayazbayeva, A.V. Shakhvorostov, T.M. Seilkhanov, V.O. Aseyev, S.E. Kudaibergenov
Published in: Bulletin of the University of Karaganda Chemistry, Issue 104 (4), 2021, Page(s) 9-20, ISSN 2518-718X
Publisher: Academician Ye.A. Buketov Karaganda University
DOI: 10.31489/2021ch4/9-20

Chitosan/Poly(2-ethyl-2-oxazoline) Films with Ciprofloxacin for Application in Vaginal Drug Delivery

Author(s): Guzel K. Abilova; Daulet B. Kaldybekov; G.S. Irmukhametova; Diara S. Kazybayeva; Zhanar A. Iskakbayeva; Sarkyt E. Kudaibergenov; Vitaliy V. Khutoryanskiy
Published in: Materials, 2020, ISSN 1996-1944
Publisher: MDPI Open Access Publishing
DOI: 10.3390/ma13071709

Phase Separation of Aqueous Poly(diisopropylaminoethyl methacrylate) upon Heating.

Author(s): Linda Salminen; Erno Karjalainen; Vladimir Aseyev; Heikki Tenhu
Published in: Langmuir, Issue 5, 2022, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.1c02224

Protein coronas coating polymer-stabilized silver nanocolloids attenuate cytotoxicity with minor effects on antimicrobial performance

Author(s): Carin C.S. Batista; Karine Panico; Jiří Trousil; Olga Janoušková; Carlos Eduardo de Castro; Petr Štěpánek; Fernando C. Giacomelli
Published in: Colloids and Surfaces B: Biointerfaces, Issue 4, 2022, ISSN 0927-7765
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfb.2022.112778

Mucoadhesive Properties of Gellan and Its Modified Derivatives

Author(s): Gul’nur Tatykhanova, Vladimir Aseyev, Sarkyt E. Kudaibergenov,
Published in: Reviews and Advances in Chemistry, Issue 10, 2020, Page(s) 140-157, ISSN 2634-8276
Publisher: Springer
DOI: 10.1134/s207997802003005x

Temperature and Salt Responsive Amphoteric Nanogels Based on N-Isopropylacrylamide, 2-Acrylamido-2-methyl-1-propanesulfonic Acid Sodium Salt and (3-Acrylamidopropyl) Trimethylammonium Chloride

Author(s): Aigerim Ye. Ayazbayeva, Alexey Shakhvorostov, Iskander Sh. Gussenov, Tulegen M. Seilkhanov, Vladimir O. Aseyev, Sarkyt E. Kudaibergenov
Published in: Nanomaterials, Issue 12 (14), 2022, Page(s) 2343, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano12142343

Self-Organization in Dilute Aqueous Solutions of Thermoresponsive Star-Shaped Six-Arm Poly-2-Alkyl-2-Oxazines and Poly-2-Alkyl-2-Oxazolines

Author(s): Tatyana Kirila, Anna Smirnova, Vladimir Aseyev, Andrey Tenkovtsev, Heikki Tenhu, Alexander Filippov
Published in: Polymers, Issue 13 (9), 2021, Page(s) 1429, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym13091429

Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

Author(s): Onugwu, A. L., Nwagwu, C. S., Onugwu, O. S., Echezona, A. C., Agbo, C. P., Ihim, S. A., Emeh, P., Nnamani, P. O., Attama, A. A. and Khutoryanskiy, V. V.,
Published in: Journal of Controlled Release, 2023, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2023.01.018

Tuning the morphology of block copolymer-based pH-triggerednanoplatforms as driven by changes in molecular weight and protocol ofmanufacturing

Author(s): Fernando A. de Oliveira, Carin C. S. Batista, Lindomar J. C. Albuquerque, Peter Cernoch, Miloš Steinhart, Vladimir Sincari, Alessandro Jager, Eliezer Jager, Fernando C. Giacomelli
Published in: Journal of Colloid and Interface Science, 2023, ISSN 0021-9797
Publisher: Academic Press
DOI: 10.1016/j.jcis.2022.12.129

Maleimide-Decorated PEGylated Mucoadhesive Liposomes for Ocular Drug Delivery

Author(s): Roman V. Moiseev; Daulet B. Kaldybekov; Sergey K. Filippov; Aurel Radulescu; Vitaliy V. Khutoryanskiy
Published in: Langmuir, 2022, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.2c02086

Protein coronas coating polymer-stabilized silver nanocolloids attenuate cytotoxicity with minor effects on antimicrobial performance

Author(s): Carin C. S. Batista, Jiří Trousil, Olga Janoušková, Carlos Eduardo de Castro, Petr Štěpánek Fernando C. Giacomelli
Published in: Colloids and Surfaces B: Biointerfaces, 2022, ISSN 0927-7765
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfb.2022.112778

Gellan gum and its methacrylated derivatives as in situ gelling mucoadhesive formulations of pilocarpine: In vitro and in vivo studies.

Author(s): Laura E. Agibayeva; Daulet B. Kaldybekov; Natalia N. Porfiryeva; V. R. Garipova; R.A. Mangazbayeva; Rouslan I. Moustafine; I. I. Semina; Grigoriy A. Mun; Sarkyt E. Kudaibergenov; Vitaliy V. Khutoryanskiy; Vitaliy V. Khutoryanskiy
Published in: International Journal of Pharmaceutics, Issue 1, 2020, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2020.119093

Electroresponsive polyelectrolyte brushes studied by self-consistent field theory

Author(s): Okrugin B.M.; Richter R.P.; Leermakers F.A.M.; Neelov I.M.; Zhulina E.B.; Borisov O.V.
Published in: Polymers, 2020, Page(s) 898, ISSN 2073-4360
Publisher: MDPI AG
DOI: 10.3390/polym12040898

Proteins and Polyampholytes Interacting with Polyelectrolyte Brushes and Microgels: the Charge Reversal Concept Revised

Author(s): Laktionov M.Y. Zhulina E.B.; Borisov O.V.
Published in: Langmuir, 2021, Page(s) 2865–2873, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.0c02837

Theory of polyelectrolyte dendrigrafts

Author(s): Borisov, O.V ; Shavykin O.V. ; Zhulina E.B.
Published in: Colloid and Polymer Science, 2020, Page(s) 951-959, ISSN 0303-402X
Publisher: Springer Verlag
DOI: 10.1007/s00396-019-04588-1

Immobilization of Methyl Orange and Methylene Blue within the Matrix of Charge-Imbalanced Amphoteric Nanogels and Study of Dye Release Kinetics as a Function of Temperature and Ionic Strength

Author(s): A.Ye. Ayazbayeva, S.Z. Nauryzova, V.O. Aseyev, A.V. Shakhvorostov
Published in: Bulletin of the University of Karaganda Chemistry, Issue 107 (3), 2022, Page(s) 127-140, ISSN 2518-718X
Publisher: Academician Ye.A. Buketov Karaganda University
DOI: 10.31489/2022ch3/3-22-4

Microfluidic-assisted synthesis of uniform polymer-stabilized silver colloids

Author(s): Carin C.S. Batista, Alessandro Jager, Brunno L. Albuquerque, Ewa Pavlova, Petr Stepanek, Fernando C. Giacomelli
Published in: Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021, ISSN 0927-7757
Publisher: Elsevier BV
DOI: 10.1016/j.colsurfa.2021.126438

Probing protein adsorption onto polymer-stabilized silver nanocolloids towards a better understanding on the evolution and consequences of biomolecular coronas

Author(s): Carin C.S. Batista, Lindomar J.C. Albuquerque, Alessandro Jäger, Petr Stepánek, Fernando C. Giacomelli
Published in: Materials Science & Engineering C, 2020, ISSN 0928-4931
Publisher: Elsevier BV
DOI: 10.1016/j.msec.2020.110850

Ophthalmic drug delivery system based on the complex of gellan and ofloxacin

Author(s): Gulnur S. Tatykhanova, Vladimir O. Aseyev, Maria Vamvakaki, Vitaliy V. Khutoryanskiy, Sarkyt E. Kudaibergenov,
Published in: Chemical Bulletin of Kazakh National University, Issue 105 (2), 2022, Page(s) 4-12, ISSN 1563-0331
Publisher: Al-Farabi Kazakh National University
DOI: 10.15328/cb1239

Investigation of the Thermogelation of a Promising Biocompatible ABC Triblock Terpolymer and Its Comparison with Pluronic F127

Author(s): Anna P. Constantinou; Valeria Nele; James J. Doutch; Joana S. Correia; Roman V. Moiseev; Martina Cihova; David C. A. Gaboriau; Jonathan Krell; Vitaliy V. Khutoryanskiy; Molly M. Stevens; Theoni K. Georgiou
Published in: Macromolecules, 2022, ISSN 0024-9297
Publisher: American Chemical Society
DOI: 10.1021/acs.macromol.1c02123

Soft Biocompatible Polymeric Nanostructures: A toolbox for Novel Generation of Nano Pharmaceuticals in Ophthalmology

Author(s): Vladimir Aseyev
Published in: Kemiauutiset KemiNyheter ChemistryNews 2020, Issue annual, 2020, Page(s) 48, ISSN 2323-7775
Publisher: Helsingin yliopiston kemian laitos

Guest from Kazakhstan: Challenges and Impressions

Author(s): Moldir Dauletbekova
Published in: Kemiauutiset KemiNyheter ChemistryNews 2020, Issue annual, 2020, Page(s) 49, ISSN 2323-7767
Publisher: Helsingin yliopiston kemian laitos

Biomolecular Coronas Coating Silver Nanoparticles: Structural Analysis and Biological Consequences

Author(s): Carin Cristina da Silva Batista
Published in: PhD Thesis, 2022
Publisher: Federal University of ABC

Poly(2-ethyl-2-oxazoline) modified gellan gum

Author(s): Janni Lavikainen
Published in: Master thesis, 2020
Publisher: University of Helsinki

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