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Common Infrastructure for National Cohorts in Europe, Canada, and Africa

Objective

Thousands of human genomes and other biomolecular datasets are now being generated in health, rather than research contexts. Centralised storage and analysis of these is no longer technically feasible for data harmonisation, curation, sharing or analysis and ethical, legal, social reasons. CINECA’s vision is a federated cloud enabled infrastructure making population scale genomic and biomolecular data accessible across international borders, accelerating research, and improving the health of individuals across continents. CINECA will leverage international investment in human cohort studies from Europe, Canada, and Africa to deliver a paradigm shift of federated research and clinical applications. The CINECA consortium will create one of the largest cross-continental implementations of human genetic and phenotypic data federation and interoperability with a focus on common (complex) disease, one of the world’s most significant health burdens. The partners represent a unique combination of scientific excellence with experience of eleven diverse cohorts and scientific projects such as the European Genome-phenome Archive, CanDIG, and H3Africa. CINECA has assembled a virtual cohort of 1.4M individuals from population, longitudinal and disease studies. Federated analyses will deliver new scientific knowledge, harmonisation strategies and the necessary ELSI framework supporting data exchange across legal jurisdictions enabling federated analyses in the cloud. CINECA will provide a template to achieve virtual longitudinal and disease specific cohorts of millions of samples, to advance benefits to patients. CINECA will leverage partner membership of standards and infrastructures like the Global Alliance for Global Health, BBMRI, ELIXIR, and EOSC driving the state of the art in standards development, technical implementation and FAIR data.

Field of science

  • /natural sciences/computer and information sciences/data science/data exchange
  • /natural sciences/biological sciences/genetics and heredity/genome

Call for proposal

H2020-SC1-2018-Single-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Address
Meyerhofstrasse 1
69117 Heidelberg
Germany
Activity type
Research Organisations
EU contribution
€ 1 548 808,75

Participants (17)

CSC-TIETEEN TIETOTEKNIIKAN OY
Finland
EU contribution
€ 491 455
Address
Keilaranta 14
02100 Espoo
Activity type
Other
HAUTE ECOLE SPECIALISEE DE SUISSE OCCIDENTALE
Switzerland
EU contribution
€ 647 500
Address
Route De Moutier 14
2800 Delemont
Activity type
Higher or Secondary Education Establishments
SIB INSTITUT SUISSE DE BIOINFORMATIQUE
Switzerland
EU contribution
€ 279 250
Address
Rue Michel Servet 1 Cmu
1206 Geneve
Activity type
Research Organisations
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 464 110
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING MCGILL UNIVERSITY
Canada
EU contribution
€ 0
Address
845 Sherbrooke Street West
H3A0G4 Montreal
Activity type
Higher or Secondary Education Establishments
The Hospital for Sick Children
Canada
EU contribution
€ 0
Address
University Avenue 555
M5G 1X8 Toronto
Activity type
Research Organisations
UNIVERSITY OF CAPE TOWN
South Africa
EU contribution
€ 247 898,75
Address
Private Bag X3
7701 Rondebosch
Activity type
Higher or Secondary Education Establishments
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 152 917,50
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
TARTU ULIKOOL
Estonia
EU contribution
€ 206 250
Address
Ulikooli 18
51005 Tartu
Activity type
Higher or Secondary Education Establishments
CLINICAGENO LIMITED
United Kingdom
EU contribution
€ 228 375
Address
Station Approach 11 Coulsdon North
CR5 2NR Coulsdon Surrey
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 185 750
Address
Carrer Doctor Aiguader 88
08003 Barcelona
Activity type
Research Organisations
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
EU contribution
€ 576 375
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 195 050
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
Simon Fraser University
Canada
EU contribution
€ 0
Address
University Drive 8888
V5A 1S6 Burnaby
Activity type
Higher or Secondary Education Establishments
THE HYVE BV
Netherlands
EU contribution
€ 261 617,50
Address
Arthur Van Schendelstraat 650
3511 MJ Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Masarykova univerzita
Czechia
EU contribution
€ 163 000
Address
Zerotinovo Namesti 9
60177 Brno Stred
Activity type
Higher or Secondary Education Establishments
BIOBANKS AND BIOMOLECULAR RESOURCES RESEARCH INFRASTRUCTURE CONSORTIUM (BBMRI-ERIC)
Austria
EU contribution
€ 350 098,75
Address
Neue Stiftingtalstrasse 2/B/6
8010 Graz
Activity type
Research Organisations